A5091780864- Sleep and Wakefulness Research
- EEG and Brain-Computer Interfaces
- Sleep and related disorders
- Memory and Neural Mechanisms
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Sleep and Work-Related Fatigue
- Action Observation and Synchronization
- Attention Deficit Hyperactivity Disorder
- Circadian rhythm and melatonin
- Neuroscience and Neuropharmacology Research
- Neuroscience and Music Perception
- Motor Control and Adaptation
- Neurobiology of Language and Bilingualism
- Hearing Impairment and Communication
- Mind wandering and attention
- Advanced Neuroimaging Techniques and Applications
- Neuroscience, Education and Cognitive Function
- Linguistics and Discourse Analysis
- Children's Physical and Motor Development
- French Language Learning Methods
- Neural Networks and Applications
- Memory Processes and Influences
- Health, Medicine and Society
Université Libre de Bruxelles
2016-2025
University of Liège
2010-2025
Neuroscience Institute
2022-2025
Cyclotron (Netherlands)
1998-2025
Neurosciences Institute
2013-2024
VIB-KU Leuven Center for Brain & Disease Research
2023
KU Leuven
2023
Cognitive Neuroimaging Lab
2017-2022
ATLAS Neuroengineering (Belgium)
2018-2020
Universidad Libre de Colombia
2017
In perceptual experiments, within-individual fluctuations in perception are observed across multiple presentations of the same stimuli, a phenomenon that remains only partially understood. Here, by means thulium–yttrium/aluminum–garnet laser and event-related functional MRI, we tested whether variability identical stimuli relates to differences prestimulus, baseline brain activity. Results indicate positive relationship between conscious low-intensity somatosensory immediately preceding...
After encoding, memory traces are initially fragile and have to be reinforced become permanent. The initial steps of this process occur at a cellular level within minutes or hours. Besides rapid synaptic consolidation, systems consolidation occurs time frame days years. For declarative memory, the latter is presumed rely on an interaction between different brain regions, in particular hippocampus medial prefrontal cortex (mPFC). Specifically, sleep has been proposed provide setting that...
Background:The minimally conscious state (MCS) is a recently defined clinical condition; it differs from the persistent vegetative (PVS) by presence of inconsistent, but clearly discernible, behavioral evidence consciousness.Objective: To study auditory processing among patients who are in an MCS, PVS, and healthy control subjects.Methods: By means 15 O-radiolabeled waterpositron emission tomography, we measured changes regional cerebral blood flow induced click stimuli 5 18 controls....
Much remains to be discovered about the fate of recent memories in human brain. Several studies have reported reactivation learning-related cerebral activity during post-training sleep, suggesting that sleep plays a role offline processing and consolidation memory. However, little is known how new information maintained processed wakefulness before while brain actively engaged other cognitive activities. We show, using functional magnetic resonance imaging, elicited learning episode...
Learning-dependent increases in sleep spindle density have been reported during nocturnal immediately after the learning session. Here, we investigated experience-dependent changes daytime EEG activity declarative of unrelated word pairs. At weekly intervals, 13 young male volunteers spent three 24 h sessions laboratory under carefully controlled homeostatic and circadian conditions. approximately midday, subjects performed either one two word-pair tasks or a matched nonlearning control...
Throughout the day, cognitive performance is under combined influence of circadian processes and homeostatic sleep pressure. Some people perform best in morning, whereas others are more alert evening. These chronotypes provide a unique way to study effects sleep-wake regulation on cerebral mechanisms supporting cognition. Using functional magnetic resonance imaging extreme chronotypes, we found that maintaining attention evening was associated with higher activity than morning region locus...
In two H 2 15 O PET scan experiments, we investigated the cerebral correlates of explicit and implicit knowledge in a serial reaction time (SRT) task. To do so, used novel application Process Dissociation Procedure, behavioral paradigm that makes it possible to separately assess conscious unconscious contributions performance during subsequent sequence generation manipulate extent which repeating sequential pattern was learned explicitly, varied pace choice task—a variable is known have...
Sleep promotes the integration of recently acquired spatial memories into cerebral networks for long term. In this study, we examined how sleep deprivation hinders consolidation process. Using functional MRI, mapped regional activity during place-finding navigation in a virtual town, immediately after learning and 3 days later, subjects either allowed regular (RS) or totally sleep-deprived (TSD) on first posttraining night. At immediate delayed retrieval, elicited increased brain an extended...
A link between sleep loss and increased risk for the development of diabetes is now well recognized. The current study investigates whether extension under real-life conditions a feasible intervention with beneficial impact on glucose metabolism in healthy adults who are chronically restricted.Intervention study.Sixteen non-obese volunteers (25 [23, 27.8] years old, 3 men).Two weeks habitual time bed followed by 6 during which participants were instructed to increase their one hour per...
Summary The European Sleep Research Society aimed to estimate the prevalence, determinants and consequences of falling asleep at wheel. In total, 12 434 questionnaires were obtained from 19 countries using an anonymous online questionnaire that collected demographic sleep‐related data, driving behaviour, history drowsy accidents. Associations quantified multivariate logistic regression. average prevalence wheel in previous 2 years was 17%. Among respondents who fell asleep, median accidents...
Circadian and homeostatic sleep-wake regulatory processes interact in a fine tuned manner to modulate human cognitive performance. Dampening of the circadian alertness signal attenuated deterioration psychomotor vigilance response elevated sleep pressure with aging change this interaction pattern. As evidenced by neuroimaging studies, both promotion impact on cognition-related cortical arousal-promoting subcortical brain regions including thalamus, anterior hypothalamus brainstem locus...
Attention deficit/hyperactivity disorder (ADHD) in children has been associated with attentional and executive problems, but also socioemotional difficulties possibly deficits Theory of Mind (ToM). Socioemotional problems ADHD are more negative prognoses, notably interpersonal, educational an increased risk developing other psychiatric disorders that emphasize the need to clarify nature their ToM deficits. In this study, we hypothesized dysfunction is largely attributable and/or Thirty-one...