- Esophageal and GI Pathology
- Diverticular Disease and Complications
- Tracheal and airway disorders
- Gastric Cancer Management and Outcomes
- Central Venous Catheters and Hemodialysis
- Colorectal Cancer Surgical Treatments
- Intestinal and Peritoneal Adhesions
- Vascular Malformations Diagnosis and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Stoma care and complications
- Biliary and Gastrointestinal Fistulas
- Airway Management and Intubation Techniques
- Vascular Procedures and Complications
- Anorectal Disease Treatments and Outcomes
- Infection Control and Ventilation
- Abdominal Surgery and Complications
- Dysphagia Assessment and Management
- COVID-19 and healthcare impacts
- Gastrointestinal disorders and treatments
- Inflammatory Bowel Disease
- Vascular anomalies and interventions
- Characterization and Applications of Magnetic Nanoparticles
- Pneumothorax, Barotrauma, Emphysema
- Cancer, Hypoxia, and Metabolism
- Ferroptosis and cancer prognosis
Mayo Clinic
2024
Mayo Clinic in Arizona
2018-2024
Government Medical College and Hospital
2006-2020
Mayo Clinic in Florida
2019
Baylor College of Medicine
2018
University of North Carolina at Chapel Hill
2018
UNC Lineberger Comprehensive Cancer Center
2018
Government Medical College and Hospital
2018
Atraumatic and precise drug delivery to arteries veins remains an unmet need in interventional medicine, with significant implications for managing vascular diseases long-term patient outcomes. Conventional endovascular methods, such as drug-coated balloons drug-eluting stents, often damage vessel endothelium compromise wall integrity, leading reduced therapeutic efficacy severe complications including restenosis thrombosis. To address these limitations, we introduce EndoBot, untethered soft...
Abstract Background and study aims Management of malignant gastrointestinal obstruction (MGIO) is more challenging in the presence peritoneal carcinomatosis (PC). Outcomes data to guide management MGIO with PC are lacking. We aimed compare clinical outcomes adverse events between endoscopic surgical palliation identify predictors stent success patients PC. Patients methods Consecutive inpatients 2000 2018 who underwent palliative surgery or enteral stenting were included. Clinical was...
The incidence of incisional hernia occurring at the port sites after laparoscopic surgery, lies between 0.02 to 3.6%[1] and usually remains unreported, until development complications.[2] Such a case is reported here problem briefly reviewed. A 55 year-old obese lady presented emergency ward, with complaints pain, redness swelling periumbilical region, for duration 4 days. She had undergone cholecystectomy our hospital years ago remained well, prior present problem. Examination revealed...
Summary Awake tracheostomy in a child with respiratory distress is an emergency life‐saving procedure when risk of airway loss after induction general anaesthesia greater due to difficult anatomy. A 10‐year‐old boy presented three days removal foreign body the throat under anaesthesia. Over subsequent days, patient had progressively increasing visible swelling neck, stridor and distress. An urgent X‐ray computed tomography scan neck revealed retropharyngeal abscess compressing trachea. Due...
To create a clinically relevant porcine model for percutaneous transluminal angioplasty (PTA) of de novo venous stenosis (VS) in an arteriovenous fistula (AVF) and to characterize the model. Twelve castrated male Yorkshire pigs (age 4-5 months, weight 40-45 kg; Manthei Farm, Elk River, MN) were obtained induce chronic kidney disease (CKD) through renal artery embolization entire left upper pole right kidney. AVF was created 28 days later by anastomosing end external jugular vein (LEJV) with...
Abstract Cancer is often driven by deregulated protein kinases pathways including breast cancer. To profile the kinome at level we are developing a kinase pulldown (KiP) proteomic platform that uses multiple inhibitors conjugated to sepharose beads for profiling. Mass spectrometry-base tryptic peptide sequencing used identify and quantify in an unbiased manner. date, have profiled analyzed kinomes of more than 50 cancer PDX model systems include all five subtypes. In these analyses begun...
Abstract Background Post-surgical complications such as leaks are the source of considerable morbidity and mortality. Success conservative interventions is highly variable. Recurrence after surgical repair also not uncommon. Our aim was to develop novel endoscopic strategies maximize negative intracavitary pressure manage in cases where conventional management either failed or were feasible. Methods We have used transluminal locking loop drains with low intermittent suction non-healing...
<h3>Introduction</h3> Anastomotic stenosis, fistulas or leaks distal to the loop ostomy either require a complex redo pelvic surgery potential conversion end ostomy, both of which are associated with significant morbidity mortality. Our aim was assess minimally invasive endoscopic approaches as primary rescue intervention in high-risk for adverse outcome (HRAO) patients who were otherwise destined permanent ostomy. <h3>Method</h3> All stent placement between May 2012 and July 2018 included....
<h3>Introduction</h3> Patients with complicated IBD have a higher risk of recurrent surgeries, prolonged hospitalizations, morbidity and mortality. We aim to review endoscopic stenting for management strictures and/or fistula as primary or rescue interventions in these patients. <h3>Methods</h3> All patients stent placement between 2011 2018 were included. Relevant demographic clinical data abstracted from the electronic medical record presented using descriptive methods. <h3>Results</h3>...