Kevin Z. Chen

ORCID: 0000-0003-4761-1506
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About
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Research Areas
  • China's Socioeconomic Reforms and Governance
  • Agricultural Innovations and Practices
  • Cardiovascular Disease and Adiposity
  • Pancreatic function and diabetes
  • Monoclonal and Polyclonal Antibodies Research
  • Single-cell and spatial transcriptomics
  • Land Rights and Reforms
  • Advanced Drug Delivery Systems
  • Rural development and sustainability
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • demographic modeling and climate adaptation
  • Rangeland Management and Livestock Ecology
  • Income, Poverty, and Inequality
  • RNA Research and Splicing
  • Chronic Lymphocytic Leukemia Research
  • Gene expression and cancer classification
  • Economics of Agriculture and Food Markets
  • CAR-T cell therapy research
  • Power Systems and Renewable Energy
  • Immune Cell Function and Interaction
  • Protein purification and stability
  • Gender, Labor, and Family Dynamics
  • Acute Lymphoblastic Leukemia research

Zhejiang University
2025

Cornell University
2023

Emory University
2021-2022

Harvard University
2020-2021

International Food Policy Research Institute
2012

Abstract Monoclonal antibodies (mAbs) are currently used for the treatment of numerous conditions including cancer, psoriasis, arthritis, and atopic dermatitis, among others. All mAbs administered by either intravenous or subcutaneous injections. Herein, use a novel ionic liquid deep eutectic solvent, choline glycolate (CGLY), as platform gastrointestinal administration therapeutic is reported. CGLY maintains stability structure TNFα antibody. significantly enhances paracellular transport...

10.1002/adfm.202002912 article EN Advanced Functional Materials 2020-06-29

ABSTRACT This study empirically examines the impact of increased competition among commute traders on performance herders in a less competitive livestock market. To achieve this, we conducted field survey and collected data 669 households from 104 villages pastoral area China. An instrument variable approach was employed to mitigate potential endogeneity concerns associated with trader competition. The results indicate an inverted U‐shaped relationship between farm‐gate prices received by...

10.1002/agr.22037 article EN Agribusiness 2025-03-06

Abstract Immunotherapies have revolutionized the treatment of B-cell acute lymphoblastic leukemia (B-ALL), but duration responses is still sub-optimal. We sought to identify mechanisms immune suppression in B-ALL and strategies overcome them. Plasma collected from children with measurable residual disease after induction chemotherapy showed differential cytokine expression, particularly IL-7, while single-cell RNA-sequencing revealed expression genes associated exhaustion cell subsets. also...

10.1038/s41598-022-16152-z article EN cc-by Scientific Reports 2022-07-13

Demographic transition due to population aging is an emerging trend throughout the developing world, and it especially acute in China, which has undergone demographic more rapidly than have most industrial economies. This paper quantifies distributional effects context of using integrated recursive dynamic computable general equilibrium model with top-down behavioral microsimulation. The results poverty inequality index indicate that a negative impact on reduction while its positive regard...

10.1080/13547860.2016.1263043 article EN Journal of the Asia Pacific Economy 2016-12-13

Abstract Quantifying RNAs in their spatial context is crucial to understanding gene expression and regulation complex tissues. In situ transcriptomic methods generate spatially resolved RNA profiles intact However, there a lack of unified computational framework for integrative analysis data. Here, we present an unsupervised annotation-free framework, termed ClusterMap, which incorporates physical proximity identity RNAs, formulates the task as point pattern problem, thus defines...

10.1101/2021.02.18.431337 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2021-02-19

Cardiovascular disease is a leading cause of mortality after liver transplantation (LT). Elevated blood pressure (BP) in LT recipients (LTRs) associated with increased cardiovascular events (CVEs) and decreased survival. Increased visit-to-visit BP variability the general population adverse outcomes. Whether outcomes LTRs unknown. We analyzed data from adult within single large transplant center United States between 2010 2016. Day-to-day first 60 days was measured using independent mean...

10.1002/lt.26370 article EN Liver Transplantation 2021-11-22

Introduction: The subcutaneous space is an attractive site for islet transplantation due to the ease of accessing, monitoring, and retrieval [1, 2]. However, achieving functional engraftment subcutaneously transplanted islets remains a challenge, insufficient vascularization major hurdle [3]. We have reported that transiently overexpressing ETV-2 (a pioneer transcription factor during vascular development) converted generic adult endothelial cells (ECs) Re-programmed Vascular ECs (R-VECs),...

10.1097/01.tp.0000994664.45858.a8 article EN Transplantation 2023-10-01

The top down public agricultural extension system in China and its early reforms during the 1990’s has left millions of farmers without access to services. An inclusive was introduced 2005 better meet diverse technology needs small farmers. Three key features experiment are 1) inclusion all as target beneficiaries, 2) effective identification farmers’ needs, 3) establishment an accountability provide advisory services This paper describes design reform initiative examines effect on Based...

10.22004/ag.econ.51902 preprint EN RePEc: Research Papers in Economics 2009-08-01
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