A5004680409- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Frailty in Older Adults
- Hepatitis C virus research
- Respiratory Support and Mechanisms
- Clinical Nutrition and Gastroenterology
- Celiac Disease Research and Management
- Body Composition Measurement Techniques
- Pharmaceutical Economics and Policy
- Antibiotics Pharmacokinetics and Efficacy
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sodium Intake and Health
- Cardiovascular Health and Risk Factors
- Hip and Femur Fractures
- Obsessive-Compulsive Spectrum Disorders
- Gastrointestinal motility and disorders
- Autopsy Techniques and Outcomes
- Chronic Myeloid Leukemia Treatments
- Diabetes and associated disorders
- Pediatric Urology and Nephrology Studies
- Diet and metabolism studies
- Clostridium difficile and Clostridium perfringens research
- Rabbits: Nutrition, Reproduction, Health
Università Campus Bio-Medico
2025
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2010-2025
Agostino Gemelli University Polyclinic
2015-2024
Università Cattolica del Sacro Cuore
2014-2019
University of Milan
1996-2016
Istituto di Fisiologia Clinica
2003
Istituti Clinici di Perfezionamento
2001
The present study was undertaken to provide a better insight into the relationship between different levels of body mass index (BMI) and changing risk for hypertension, using an unselected sample participants assessed during Longevity Check-up 7+ (Lookup 7+) project. Lookup is ongoing cross-sectional survey started in June 2015 conducted unconventional settings (i.e., exhibitions, malls, health promotion campaigns) across Italy. Candidate are eligible enrolment if they at least 18 years age...
The maintenance of muscle function into late life protects against various negative health outcomes. present study was undertaken to evaluate the impact habitual physical activity and exercise types on performance across ages in community-living adults. Longevity check-up 7+ (Lookup 7+) project is an ongoing cross-sectional survey conducted unconventional settings (e.g., exhibitions, malls, promotion campaigns Italy) that began June 1st 2015. designed raise awareness general population major...
Dementia is a major cause of poor quality life, disability, and mortality in old age. According to the geroscience paradigm, mechanisms that drive aging process are also involved pathogenesis chronic degenerative diseases, including dementia. The dissection such therefore instrumental providing biological targets for interventions new sources biomarkers. Within several biomarkers have been discovered can be measured blood allow early identification individuals at risk cognitive impairment....
Malnutrition is common in older adults, and its risk greater those living with dementia. Relative to cognitively healthy peers, the prevalence of malnutrition also increased individuals early stages cognitive disorders owing pathophysiological, cognitive, psychosocial changes related impairment. associated adverse health outcomes, including faster functional decline. Here, we provide an overview prevention, assessment, management a special focus on aspects that are important consider...
Abstract Cardiovascular health metrics (CHMs) may predict disability independent of vascular events. Though, the link between CHMs and physical performance is unclear. This relationship was explored using data from Longevity check-up (Lookup) 7+ project. Lookup an ongoing cross-sectional survey conducted in unconventional settings across Italy. People who are at least 18-year-old provide written informed consent eligible. [i.e., smoking status, healthy diet, body mass index (BMI), blood...
Background and aims The COVID-19 pandemic represents a source of stress potential burnout for many physicians. This single-site survey aimed at assessing perceived risk to develop syndrome among physicians operating in COVID wards. Methods longitudinal evaluated 51 the team Gemelli Hospital, Italy. Participants were asked complete Maslach Burnout Inventory (MBI) Perceived Stress Questionnaire on short run (PSQs) (referring past 7 days) baseline (T0) then four weeks (T1-T4). long (PSQl) 2...
Research on pediatric hand exoskeletons remains limited compared to that devices for adults. This paper presents the design and experimental validation of a customizable finger module, part exoskeleton tailored individual anatomical features. The module aims assist flexion in children with mild spasticity during activities daily living. A patient-specific methodology was applied case 12-year-old child. integrates compliant dorsal structures cable-driven transmission rigid anchoring elements...
Pulmonary function tests were performed on 62 transfusion-dependent patients with thalassemia major, ranging in age from 8 to 33 years, and receiving chelation therapy desferrioxamine or deferiprone. Percent predicted values for FVC, FEV1, PEF significantly reduced, whereas FEV1/FVC maximal expiratory flow at 25% FVC within normal limits, indicating a restrictive disease. Both FEV1 negatively correlated transfusional iron burden as indexed by age. Single-breath carbon monoxide transfer...
Short stature and growth hormone deficiency (GHD) are frequent occurrences in thalassaemic children, while data on the prevalence of GHD adult patients lacking. Therefore, we elected to study insulin-like factor-I (GH-IGF-I) axis a large group subjects.Cross-sectional 94 (69 with thalassaemia major 25 intermedia, 39 men 55 women, aged 31.5 +/- 6.8 years, sex steroid replacement when necessary).All underwent GHRH (1 microg/kg as an i.v. bolus) plus arginine (0.5 g/kg 30 min infusion) testing....
Patients with thalassemia are at increased risk for infections, especially after undergoing splenectomy. Vaccinations and antimicrobial prophylaxis recommended in these patients, but the optimal immunization schedule Haemophilus influenzae type b (Hib) vaccine is unknown. The immunogenicity of a conjugate Hib was investigated 57 patients thalassemia, 32 whom had undergone Anti-capsular antibodies to (anti-polyribosylribitol phosphate) were measured before vaccination 2, 6, 12, 24, 36 months...
Quality of life (QoL) assessment in children with coagulation disorders is a relatively unstudied area. While hemophilia-specific questionnaires (such as Haemo-QoL) are available, no instrument for idiopathic thrombocytopenic purpura (ITP) has been validated yet. A disease-specific questionnaire ITP was therefore developed (ITP-QoL) three phases: (a) preparatory phase; (b) developmental (c) pilot testing phase. Since dimensions Haemo-QoL were considered important ITP, items adapted,...