A5101929067- CAR-T cell therapy research
- Gastrointestinal Tumor Research and Treatment
- Hemoglobinopathies and Related Disorders
- Integrated Circuits and Semiconductor Failure Analysis
- Hair Growth and Disorders
- Iron Metabolism and Disorders
- Stress Responses and Cortisol
- Acute Myeloid Leukemia Research
- Pericarditis and Cardiac Tamponade
- Multiple Myeloma Research and Treatments
- Sarcoma Diagnosis and Treatment
- Extracellular vesicles in disease
- Histone Deacetylase Inhibitors Research
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Platelet Disorders and Treatments
- Metastasis and carcinoma case studies
- Bone and Joint Diseases
- Cardiac tumors and thrombi
- Textile materials and evaluations
- Lung Cancer Research Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Ear and Head Tumors
- Cancer Immunotherapy and Biomarkers
- Trypanosoma species research and implications
Dana-Farber Cancer Institute
2023-2025
Sapporo Medical University
1997-2019
Muroran Institute of Technology
2016
University of Alberta
1997
University of Maryland, Baltimore
1994
Kitasato University
1992
Background: CAR-T cell therapy provides transformative outcomes for patients with relapsed/refractory (R/R) large B lymphoma (LBCL). However, a fraction of remains at risk relapse, underlying the need to uncover mechanisms resistance and predictive biomarkers. We leveraged ZUMA-1, -6 -7 studies R/R LBCL discover product features associated outcome [Axicabtagene Ciloleucel (axi-cel)]. explored ligand-receptor interactions between cells tumor microenvironment, identifying CD27-CD70 TIGIT-PVR...
Complete remission by induction therapy in acute myelogenous leukemia (AML) can be achieved due to improvements supportive and optimized therapy. However, more than 20% of patients will still need undergo salvage therapy, most have a poor prognosis. Determining the specificity drugs cells is important since this maximize dose chemotherapeutic agents that administered AML patients. In turn, would expected lead reduced drug toxicity its increased efficacy. We targeted Notch-1 positive...
Carcinoma ex pleomorphic adenoma (CXPA) is a rare histologic subtype of lacrimal gland and submandibular cancer. Currently, there no standard treatment for metastatic CXPA, although some case reports have explored the role targeted agents in chemotherapy. A few histopathologic analyses shown that these tumors overexpress human epidermal growth factor receptor-2 (HER2), suggesting potential HER2-based therapy. We report here two cases CXPA were treated with trastuzumab-based chemotherapy (IRB...
// Soushi Ibata 1, 2 , Masayoshi Kobune 1 Shohei Kikuchi Masahiro Yoshida Shogo Miura Hiroto Horiguchi Kazuyuki Murase Satoshi Iyama Kohichi Takada Koji Miyanishi and Junji Kato Department of Hematology, Sapporo Medical University School Medicine, Sapporo, Japan Oncology, Correspondence to: Kobune, email: mkobune@sapmed.ac.jp Keywords: multiple myeloma; NUP133; prognostic factor Received: January 06, 2018 Accepted: April 24, Published: May 18, ABSTRACT Recent advances in plasma cell biology...
The gastrointestinal tract is a common site for the occurrence of non-Hodgkin's lymphoma (NHL). NHL with lesions may lead to clinically relevant intestinal complications such as obstruction, perforation, and exsanguination during course disease. Consequently, patients are often examined by means upper lower endoscopy at initial visit. There no clear guidelines regarding which should undergo capsule (CE) balloon enteroscopy detecting small lesions. We retrospectively feasibility in using...
Department of Psychiatry, Kitasato University School Medicine 2-1-1, Asamizodai, Sagamihara, Kanagawa, 228, Japan.
Jimbow, K; Thomas, P D; Gili, A; Singh, S; M; Miura, Shokravi, M Author Information