Objective: To develop a conceptually and semantically valid English version of French disease-specific measure quality life for children, adolescents, adults with cystic fibrosis (CF).

The relationship between socioeconomic variables and the health-related quality of life (HQL) children with asthma their caregivers was examined. Pediatric Asthma Quality Life Questionnaire (PAQLQ) Caregivers (PACQLQ) were administered to 99 pediatric asthmatic patients in two specialty clinics. Sociodemographic data obtained from medical records additional questions. sociodemographic HQL determined using multiple linear regression. mean patient age 12.6+/-2.1 years, more male a minority...

Successful asthma management in children requires an appropriate division of responsibility for tasks between patient and their family. Non-adherence may result without assignment or acceptance these tasks. This study explored the relationship selected child, caregiver, family, characteristics self-management activities. Child caregiver perceived were determined described via means mean summary scores. Child, interview chart review by proportions. Pearson's correlation coefficient (r)...

ABSTRACT This article discusses how determining the viscoelastic properties of cover material a conveyor belt, using different rheological test modes, can result in significant differences for same and testing conditions. The are applied to two mathematical models used predict compare indentation rolling resistance performance rubber compounds. demonstrates inaccuracies could with higher being selected conveying system, making power consumption system larger than necessary. © 2014 Wiley...

This analysis of gentamicin pharmacokinetics involved 15 neonates supported by extracorporeal membrane oxygenation (ECMO). Two sets blood samples were obtained from each neonate while ECMO. The mean volume distribution, elimination half-life, and clearance calculated the first set 0.62 liters/kg, 7.6 hours, 1.17 ml/kg/minute, respectively. Mean values second 0.61 7.9 hours 0.99 There no statistical differences (p > 0.05) between samples. A comparison our results with those others involving...

Tobramycin was administered to 52 patients, ages 2 months 27 years, with cystic fibrosis during acute exacerbation of Pseudomonas-re-lated pulmonary infection. Elimination pharmacokinetics tobramycin characterized for each patient after intravenous administration using a standardized infusion technique. The minimal inhibitory concentration determined Pseudomonas strains isolated from 26 the patients. pharmacokinetic parameters individual were used adjust dose and dosing interval maintain...

We attempted to determine the responsiveness and validity of Quality Well‐Being (QWB) scale in 20 consecutive children adolescents with cystic fibrosis. The QWB score was determined for 6‐day periods immediately before after hospital admission, at 6‐ 12‐month follow‐up. With instrument's zero‐1, indicated by significant changes (0.09), physical (0.019), social (0.021), symptom‐problem complexes (0.04) domains, all pulmonary function tests from treatment an acute exacerbation. Only complex...

This study determined retention by children of drug delivery device technique between visits. Patients had asthma requiring the daily use at least one medication device. Seventy-two patients completed study; 24 used only metered dose inhaler (MDI) (group 1), while 48 MDI and 1 other 2). or caregivers were initially instructed on demonstrated correct their device(s). At next visit, they for each follow-up, 36% correctly performed all components MDI. Group (50%) was higher than group 2 (29%)....

A 40‐month‐old child was sedated with a fentanyl and midazolam infusion for 7 days. After the drugs were discontinued he became unresponsive globally aphasic, had marked thrombocytosis. He hospitalized 4 weeks, during which time his motor cognitive status slowly improved, almost returned to baseline at of discharge. Severe neurologic abnormalities have been reported fentanyl, administered separately or together, seem be consequence withdrawal syndrome. Of interest, this patient reactive...

A comprehensive asthma program involving a pharmacist and physician evaluated quality of life (QOL) for children with the relationship between changes in QOL traditional outcomes. The consisted aggressive medical management education program. Children were from an inner‐city population who had been referred to specialist. Twenty 29 enrolled available 1‐year follow‐up. Significant improvements seen overall scores each domain instrument, which exceeded minimal important difference. strong was...

A preliminary study was conducted at three hospitals—two private hospitals and one public teaching institution—to collect data on the time cost involved with provision of inpatient clinical pharmacy services. Pharmacists were assigned to medical units within each hospital, representing a total 116 beds. The pharmacist participated unit seven days week varying times during day. collected 62-, 40- 44-day periods hospitals. Results revealed that patient could receive all four services—admission...

ABSTRACT OBJECTIVES The purpose of this study is to determine pharmacists' perceived knowledge and expertise required make recommendations regarding selected pediatric topics. METHODS A questionnaire was distributed 400 pharmacists practicing in community, hospital, home care settings. This instrument explored their knowledge, expertise, comfort providing related 38 impact responder demographics on differences for each topic were evaluated. RESULTS Ninety-five (24%) questionnaires returned...

Seventy-five hospitalized pediatric patients and 40 discharged with prescriptions were studied to determine the role of a pharmacist on unit general hospital. During 120-hour period was stationed patient care unit, 31 possible medication problems involving 14 detected while monitoring charts, 12 taking admission drug histories. Eight (25.8%) six charts considered by both medical director pediatrics be significant. Seven histories allergies which had not been or recorded nursing personnel....

This analysis of gentamicin pharmacokinetics involved 15 neonates supported by extracorporeal membrane oxygenation (ECMO). Two sets blood samples were obtained from each neonate while ECMO. The mean volume distribution, elimination half-life, and clearance calculated the first set 0.62 liters/kg, 7.6 hours, 1.17 ml/kg/minute, respectively. Mean values second 0.61 7.9 hours 0.99 There no statistical differences (p > 0.05) between samples. A comparison our results with those others involving...

In December 1969 through February 1970, a pilot study of 100 patients at community pharmacy combined with diagnostic laboratory was undertaken to determine the incidence drug-diagnostic test interferences in outpatients. It determined that 58 (25.6%) out total 226 tests were involved possible drugdiagnostic 78 who found be taking medications. The further detected, 29 (50%) yielded results corresponding those indicated literature. Forty-one interferences. An average 1.76 drugs being taken by...

This study determined the extent and impact of tobramycin pharmacokinetic variability in cystic fibrosis patients. Twenty patients were hospitalized twice half-life, volume distribution clearance during Weeks 1 2 both admissions. A difference (P less than 0.05) existed between each admission, but not admissions, for half-life. No weeks or admissions distribution. significant correlations within an admission half-life clearance. There was a correlation second first admission. The percents...

The Seralyzer reflectance photometer was evaluated in three ambulatory settings. Of the total 99 assays pediatric general medicine clinic, 47 were below therapeutic range, and 20 patients noncompliant. There 13 low nine high levels along with 22 noncompliant detected from a of 109 allergy clinic. physician's office documented 43 four 10 105 assays. mean time required for results both clinic minutes. Regression analysis finger-stick venipuncture split samples indicated strong correlation...