A5046872886- Glioma Diagnosis and Treatment
- Virus-based gene therapy research
- Pituitary Gland Disorders and Treatments
- Mesenchymal stem cell research
- Cancer Immunotherapy and Biomarkers
- Trypanosoma species research and implications
- Cancer, Stress, Anesthesia, and Immune Response
- Brain Metastases and Treatment
- CAR-T cell therapy research
- Lysosomal Storage Disorders Research
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Healthcare professionals’ stress and burnout
- Cancer, Hypoxia, and Metabolism
- Public Health in Brazil
- RNA Interference and Gene Delivery
- Innovations in Medical Education
- Meningioma and schwannoma management
- Empathy and Medical Education
- Adrenal and Paraganglionic Tumors
- Cerebrospinal fluid and hydrocephalus
- Soft tissue tumors and treatment
Universidade Federal de São Paulo
2015-2025
Hospital do Coração
2021-2025
Hospital Bandeirantes
2013
Glioblastoma (GBM) is an infiltrative tumor that difficult to eradicate. Treating GBM with mesenchymal stem cells (MSCs) have been modified the HSV-Tk suicide gene has brought significant advances mainly because MSCs are chemoattracted and kill via a bystander effect. To use this strategy, abundantly present adipose-tissue-derived (AT-MSCs) were evaluated for treatment of in mice. AT-MSCs prepared using mechanical protocol avoid contamination animal protein transduced lentiviral vector. The...
The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There high morbidity associated with surgical resection of jugulare. Radiosurgery play relevant role as therapeutic option in these tumors and its use has grown popularity. authors describe retrospective series 15 patients reviewed the literature about tumors.We retrospectively data treated stereotactic linear accelerator radiosurgery (LINAC) between 2006 2011.The average volume was 18.5 cm(3)....
Abstract Background Spirituality has religious and nonreligious dimensions is often linked to well-being, positive emotions, connection meaning in life. Both empathy resilience are important medical training future professional practice since they considered core skills related professionalism patient care. Our study aimed understand the relationships among spirituality, resilience, students. We also determine whether there differences by gender between students different years of a program....
Background Mucopolysaccharidose type I (MPSI) is a lysosomal monogenic disease caused by mutations in the gene for α- l-iduronidase (IDUA). MPSI patients need constant supply of IDUA to alleviate progression disease. transfer using integrative vectors might provide definitive solution and support advancement clinical trials, although studies have not yet been satisfactory. To achieve stable expression vivo, phiC31 was tested present study. Methods Several plasmid were constructed –/– mice...
Glioblastoma (GBM) is the most common and lethal primary intracranial tumor. Because GBM highly invasive diffusely infiltrates brain, a complete resection of tumor unfeasible. The gene encoding thymidine kinase from herpes simplex virus-1 (HSV-Tk) commonly used suicide in preclinical clinical trials against GBM. Treating with mesenchymal stem cells (MSCs) that have been modified HSV-Tk has brought significant advances mainly because MSCs are chemoattracted to kill via bystander effect....
Radiosurgery (SRS) or Stereotactic Radiotherapy (SRT) is a standard procedure as second-line treatment in patients with pituitary adenoma, when cure the initial surgical and/or hormonal not possible. When compared to conventional (RT), stereotactic shows reduction of risks especially visual and alterations. The prognosis this type intervention long-term control tumor growth excellent 95 100% cases. In who have secreting tumors, normalization elevated hormone levels are observed (40 92%)....