A5007018009- Genomics and Phylogenetic Studies
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- Phytochemistry and biological activity of medicinal plants
- Chromatography in Natural Products
- Pharmacological Effects of Natural Compounds
Jiangxi Agricultural University
2023-2024
Guangzhou University of Chinese Medicine
2022
Abstract Understanding the community structure and functional capacity of lower respiratory tract microbiome is crucial for elucidating its roles in diseases. However, there are few studies about it owing to difficulty obtaining microbial samples from tract. Here we collected 745 porcine by harvesting 675 pigs, constructed a gene catalog containing 10,337,194 nonredundant genes, which only 30% could be annotated taxonomically. We obtained 397 metagenome-assembled genomes (MAGs) including 111...
Background. Tao-He-Cheng-Qi Formula (THCQF) is a traditional Chinese medicine that has been proven to have antitumor effects. The aim of this study was elucidate the molecular targets and mechanisms THCQF against colon cancer construct prognostic model based on network pharmacology, bioinformatics analysis, in vitro experiments. Methods. Potential compounds were retrieved from Traditional Medicine Systems Pharmacology Bioinformatics Analysis Tool for Molecular Mechanism databases....
Understanding the community structure of lower respiratory tract microbiome is crucial for elucidating its roles in diseases. However, there are few studies about this topic due to difficulty obtaining microbial samples from both healthy and disease individuals. Here, using 744 high-depth metagenomic sequencing data 675 well-phenotyped pigs, we constructed a lung gene catalog containing largest scale 10,031,593 nonredundant genes date, 44.8% which novel. We obtained 356 metagenome-assembled...