A5073254211- Ophthalmology and Visual Impairment Studies
- Urticaria and Related Conditions
- Spondyloarthritis Studies and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Corneal surgery and disorders
- Inflammatory Bowel Disease
- Retinal Imaging and Analysis
- Psoriasis: Treatment and Pathogenesis
- Rheumatoid Arthritis Research and Therapies
- Autoimmune Bullous Skin Diseases
- Mast cells and histamine
- Intraocular Surgery and Lenses
- Asthma and respiratory diseases
- Retinal Diseases and Treatments
- Pelvic floor disorders treatments
- Microscopic Colitis
- Healthcare cost, quality, practices
- Neonatal Respiratory Health Research
- Frailty in Older Adults
- Ophthalmology and Visual Health Research
- Pesticide Exposure and Toxicity
- Stroke Rehabilitation and Recovery
- Celiac Disease Research and Management
- Older Adults Driving Studies
- Dermatology and Skin Diseases
Novartis (Switzerland)
2019-2024
Novartis (Canada)
2014-2018
Institut Universitaire de Gériatrie de Montréal
2013
Université de Montréal
2013
Presbyopia is defined as the age-related deterioration of near vision over time which experienced in 80% people aged 40 years or older. Individuals with presbyopia have difficulty tasks that rely on vision. It not currently possible to stop reverse aging process causes presbyopia; generally, it corrected glasses, contact lenses, surgery, use a magnifying glass.This study aimed explore how individuals used social media describe their experience regard symptoms and impacts quality life.Social...
To compare the insights obtained about experience of individuals with presbyopia (age-related impaired near vision) across three different sources qualitative data: a structured targeted literature review, social media listening (SML) and concept elicitation (CE) interviews healthcare professionals (HCPs). The number concepts identified, depth data, cost time implications, value patient generated were explored compared for each method.
To assess whether stress or mixed urinary incontinence (UI) is associated with deficits in executive functioning among community-dwelling women.An observational study comparing the performance, using multivariate analyses of variance (MANOVAs) and Bonferroni post hoc test, continent women UI during control tasks.The research center Institut universitaire de gériatrie Montréal.One hundred fifty-five aged 60 older participated study.Based on Urogenital Distress Inventory (UDI), participants...
The study evaluates the cost-effectiveness of secukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin (IL)-17A, vs currently licensed biologic treatments in patients with active psoriatic arthritis (PsA) from Canadian healthcare system perspective.A decision analytic semi-Markov model evaluated secukinumab 150 mg and 300 compared to subcutaneous biologics adalimumab, certolizumab pegol, etanercept, golimumab, ustekinumab, intravenous infliximab biosimilar...
To assess the cost-effectiveness of interleukin (IL)-17A inhibitor secukinumab vs currently licensed biologic therapies in ankylosing spondylitis (AS) patients from a Canadian healthcare system perspective.A decision analytic model (semi-Markov) evaluated 150 mg compared to certolizumab pegol, adalimumab, golimumab, etanercept and biosimilar, infliximab biosimilar biologic-naïve population, over 60 years time horizon (lifetime). The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI...
Abstract Background The Near Visual Acuity Questionnaire Presbyopia (NAVQ-P) is a patient-reported outcome (PRO) measure that was developed in phakic presbyopia population to assess near vision function impacts. study refined and explored the psychometric properties score interpretability of NAVQ-P additional PRO items assessing correction independence (NVCI), satisfaction (NVS), preference (NVCP). Methods This validation conducted using data collected as part Phase IIb clinical trial...
Abstract Background Presbyopia is the age-related deterioration in ability to focus on close objects. In order develop a patient-reported outcome (PRO) instrument assess near vision functioning, Near Activity Visual Questionnaire (NAVQ) was adapted incorporate modern technology (e.g. smartphones) and be appropriate for use phakic presbyopia, leading development of NAVQ-Presbyopia (NAVQ-P). Additional single-item instruments correction independence (NVCI), preference (NVCP), satisfaction...
Abstract Background Presbyopia is defined as the age-related deterioration in ability to focus on close objects, causing difficulty with near vision tasks. The study aim was understand lived experience of phakic presbyopia and identify all relevant visual function symptoms associated functional impacts. Methods Fifty individuals clinician-confirmed (US n = 30, France 10, Germany 10) seven healthcare professionals (HCPs) participated in-depth, face-to-face, qualitative concept elicitation...
Limited evidence exists on the burden of chronic heart failure (CHF) in terms reduced vs. preserved ejection fraction (HFrEF HFpEF) and NYHA classification. This study aims to determine health care resource utilization associated with CHF, both for HFrEF (≥45%) HFpEF (<40%) according class. Retrospective analysis a longitudinal population-based medical records database from southwestern Ontario was conducted. Records contain chart-abstracted information such as diagnosis, physician visits...
<sec> <title>BACKGROUND</title> Presbyopia is defined as the age-related deterioration of near vision over time which experienced in 80% people aged 40 years or older. Individuals with presbyopia have difficulty tasks that rely on vision. It not currently possible to stop reverse aging process causes presbyopia; generally, it corrected glasses, contact lenses, surgery, use a magnifying glass. </sec> <title>OBJECTIVE</title> This study aimed explore how individuals used social media describe...
<h3>Background</h3> Psoriatic arthritis (PsA) is a heterogeneous multifaceted inflammatory associated with psoriasis (PsO). PsA causes substantial disease burden and has significant societal health impact. Accurately determining the prevalence of can be difficult due to variations in presentation over time, changes classification specialty treating physician. <h3>Objectives</h3> To perform systematic literature review identify potential determinants PsA. <h3>Methods</h3> A search...
A previous study indicated that after one year, the proportion of patients with a dose augmentation was higher infliximab than adalimumab. The objective this to analyze, in real world setting, trends changes over three-year period retrospective cohort conducted using data from Regie de l'assurance maladie du Quebec (RAMQ) for randomly selected group CD diagnosis, who had initiated (6month washout period) adalimumab or between February 2008 and March 2011. For adalimumab, increase considered...