- Pulmonary Hypertension Research and Treatments
- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Cardiovascular Issues in Pregnancy
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Transplantation: Methods and Outcomes
- Viral Infections and Immunology Research
- Heart Failure Treatment and Management
- Coronary Artery Anomalies
- Antimicrobial Resistance in Staphylococcus
- Cardiovascular Function and Risk Factors
- Vascular Anomalies and Treatments
- Anesthesia and Neurotoxicity Research
- Cardiac electrophysiology and arrhythmias
- Nitric Oxide and Endothelin Effects
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Neuroscience of respiration and sleep
- SARS-CoV-2 and COVID-19 Research
- Vascular anomalies and interventions
Onassis Cardiac Surgery Center
1998-2022
Heinrich Heine University Düsseldorf
1994
Myocarditis in response to COVID-19 vaccination has been reported since early 2021. In particular, young male individuals have identified exhibit an increased risk of myocardial inflammation following the administration mRNA-based vaccines. Even though first epidemiological analyses and numerous case reports investigated potential relationships, endomyocardial biopsy (EMB)-proven cases are limited. Here, we present a comprehensive histopathological analysis EMBs from 15 patients with reduced...
<b>Objective:</b> To evaluate the long-term clinical and exercise effect of chronic oral administration non-selective endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension (PAH) related to congenital heart disease (CHD). <b>Design:</b> Extension a preceding prospective non-randomised open study on treatment PAH CHD. <b>Setting:</b> A tertiary referral centre for cardiology. <b>Patients:</b> 19 original 21 mean (standard deviation (SD)) age 22 (3) years (13...
Operative strategies and early results concerning repair of Total Anomalous Pulmonary Venous Connection (TAPVC) are relatively well known. Less defined data available to evaluate the long-term outcome. We would therefore like contribute our in this presentation.Between 1958 1992 52 consecutive patients aged two days 42 years (15 neonates, 16 infants, 9 children 12 adults) with TAPVC were operated on. The collected retrospectively from records. In 24 patients, a current follow-up study was...
Seventy-two children were treated with propafenone between 1980 and 1990. The mean age was 34 months (range 0-192). Arrhythmias included atrioventricular re-entry tachycardia in 32 patients (44%), atrial flutter 16 (22%), or junctional ectopic 10 (14%), tachycardias three (4%) ventricular arrhythmias 11 (16%). efficacy of oral treatment good atrio-ventricular (80%), (71%) (83%); it poor (40%). dose 13.5 mg.kg-1. day-1. Dosage serum levels did not differ whether the successfully not. No...
Objective: If the pulmonary artery (PA) tree in patients with Fallot's tetralogy (TOF) is extremely hypoplastic, a shunt procedure may be difficult and not desirable because of side-effects. Moreover, failing catch-up growth annulus well known. In severe form TOF, we performed palliative transannular patching right ventricular outflow tract. The early long-term follow-up was evaluated. Methods: Eleven (93 days (10–245 days); 3.5±0.7kg (2.5–4.3kg)) had highly symptomatic TOF (Hb: 18±2g/dl,...
<b>Objective:</b> To evaluate the acute haemodynamic effect of BQ-123, a selective endothelin A receptor antagonist, in severe chronic pulmonary arterial hypertension (PAH) primary or autoimmune origin related to congenital heart disease. <b>Design:</b> Prospective open clinical study. <b>Setting:</b> Cardiology tertiary referral centre. <b>Patients:</b> 26 patients with PAH were studied, mean (SEM) age 29 (3) years (range 4–71 years), artery pressure 68 (4) mm Hg, and vascular resistance...