A5102819274- Pregnancy and preeclampsia studies
- Influenza Virus Research Studies
- Plant and animal studies
- Congenital heart defects research
- Respiratory viral infections research
- Insect and Arachnid Ecology and Behavior
- Cardiovascular Function and Risk Factors
- Pancreatic and Hepatic Oncology Research
- Insect symbiosis and bacterial influences
- T-cell and B-cell Immunology
- Advanced Memory and Neural Computing
- Cancer Risks and Factors
- Magnetic Properties and Applications
- Insect behavior and control techniques
- Coronary Artery Anomalies
- Genetics, Bioinformatics, and Biomedical Research
- Biotechnology and Related Fields
- Adipose Tissue and Metabolism
- Congenital Heart Disease Studies
- Cancer Genomics and Diagnostics
- Birth, Development, and Health
- Rheumatoid Arthritis Research and Therapies
- Magnetic properties of thin films
- Lung Cancer Treatments and Mutations
- Metabolism, Diabetes, and Cancer
Janssen (Belgium)
2022
KU Leuven
2016-2018
IMEC
2018
Universitair Ziekenhuis Leuven
2018
Abstract Cardiovascular disease associated with metabolic syndrome has a high prevalence, but the mechanistic basis of cardiomyopathy remains poorly understood. We characterised cardiac transcriptome in murine (MetS) model (LDLR−/−; ob/ob, DKO) relative to healthy, control heart (C57BL/6, WT) and transcriptional changes induced by ACE-inhibition those hearts. RNA-Seq, differential gene expression transcription factor analysis identified 288 genes differentially expressed between DKO WT...
T-705 (favipiravir) is a new antiviral agent in advanced clinical development for influenza therapy. It supposed to act as an alternative substrate the viral polymerase, causing inhibition of RNA synthesis or virus mutagenesis. These mechanisms were also proposed ribavirin, established and broad drug that shares structural similarity with T-705. We here performed comparative analysis effects ribavirin on host cell functions. Influenza virus-infected cultures exposed during single serial...
Objective CD4+ T cells are implicated in rheumatoid arthritis (RA) pathology from the strong association between RA and certain HLA class II gene variants. This study was undertaken to examine synovial cell receptor (TCR) repertoire, phenotypes, specificities small joints of patients at time diagnosis before therapeutic intervention. Methods Sixteen patients, whom 11 were anti–citrullinated protein antibody (ACPA)–positive 5 ACPA–, underwent ultrasound‐guided biopsy a joint (n = 13) or...
Analogous device parameters in both the parallel (P) and anti-parallel (AP) states ensure a symmetric spin-transfer-torque magnetic random-access memory operation scheme. In this study, however, we observe an increasing asymmetry performance metrics with operating temperature of bottom-pinned perpendicular tunnel junction (p-MTJ) devices. A temperature-dependent increase contribution stray field is observed tunneling magnetoresistance loop analysis. The switching current for P-to-AP...