A5101837814- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
- RNA Research and Splicing
- Prostate Cancer Treatment and Research
- RNA modifications and cancer
- Circular RNAs in diseases
- Ferroptosis and cancer prognosis
The First People’s Hospital of Lianyungang
2020-2021
Xuzhou Medical College
2012-2020
Second People’s Hospital of Huai’an
2012
Abstract Background Previous studies have shown that lncRNA LINC00662 plays an important role in pathogenesis of malignancies. The purpose this study was to elucidate the regulatory mechanism esophageal squamous cell carcinoma (ESCC). Methods In study, investigated by RT‐qPCR. MTT, transwell and dual luciferase reporter assays. Results Upregulation found ESCC associated with worse clinical outcomes patients. More importantly, knockdown restrained proliferation, migration invasion ESCC....
Accumulating evidence indicates that miRNAs (miRs) play crucial roles in the modulation of tumors development. However, accurately mechanisms have not been entirely clarified. In this study, we aimed to explore role miR-200b development gastric cancer (GC).Western blot and RT-PCR were applied detect epithelial-mesenchymal transition (EMT) marker expression mRNA expression. Transwell assay was used for measuring metastasis invasiveness GC cells. TargetScan system, luciferase reporter assay,...