- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- MRI in cancer diagnosis
- Ultrasound and Hyperthermia Applications
- Liver Disease and Transplantation
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Microbial Inactivation Methods
- Ultrasound in Clinical Applications
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Central Venous Catheters and Hemodialysis
- Advanced X-ray and CT Imaging
- Aortic aneurysm repair treatments
- Organ Transplantation Techniques and Outcomes
- Medical Imaging and Pathology Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Vascular Procedures and Complications
- Ultrasound Imaging and Elastography
- Thyroid Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Abdominal vascular conditions and treatments
- COVID-19 diagnosis using AI
University Hospital Regensburg
2016-2025
University of Regensburg
2011-2025
University Medical Center
2011-2024
Bayreuth Medical Center
2024
Massachusetts General Hospital
2024
Brandenburg University of Technology Cottbus-Senftenberg
2023
Ludwig-Maximilians-Universität München
2015
University Hospital Heidelberg
2015
Federal Ministry of Education and Research
2015
Heinrich Heine University Düsseldorf
2015
Mammograms of 35 patients suspected breast cancer were taken along craniocaudal and mediolateral projections with a dual-wavelength scanning laser pulse mammograph measuring time-resolved transmittance. Among 26 tumors known from routine clinical diagnostics, 17 detected retrospectively in optical mammograms. Effective tumor properties derived homogeneous model used to deduce physiological information. All exhibited increased total hemoglobin concentration decreased or unchanged blood oxygen...
To evaluate the efficacy of a self-expanding plastic stent in treatment thoracic leaks after esophagectomy for cancer.Anastomotic are major cause morbidity and mortality esophageal resection. Treatment options range from aggressive surgery to conservative management, but there remains much controversy on best treatment.Over 6-year period (1998-2003), esophagogastric were observed 19 204 patients (9.3%) esophagectomy. Between 1998 2000, anastomotic managed by reexploration (n = 7) or 3)....
Goal of the study was assessment AI-assisted diagnosis solid thyroid foci with multimodal modern ultrasound imaging. 50 patients (26-81 years, 54.7±13.1 years) were included in study. Multimodal imaging by means B-mode linear probe (4-12 MHz) option automated documentation findings AI, supplementary Ultra MicroAngiography (UMA) used. Macrovascularisation assessed dynamic contrast ultrasonography (CEUS) parametric evaluation and perfusion analysis, microvascularization combined strain shear...
To assess the differences between normal and cirrhotic livers by means of T1 mapping liver parenchyma on gadoxetic acid (Gd-EOB-DTPA)-enhanced 3 Tesla (3T) MR imaging (MRI).162 patients with (n = 96) 66; Child-Pugh class A, n 30; B, 28; C, 8) underwent Gd-EOB-DTPA-enhanced 3T MRI. obtain maps, two TurboFLASH sequences (TI 400 ms 1000 ms) before 20 min after Gd-EOB-DTPA administration were acquired. relaxation times reduction rate pre- post-contrast enhancement images measured.The for MRI...
Background:This study is an outcome evaluation of the Drug-Eluting-Bead-Chemoembolization (DEB TACE) compared to conventional TACE (cTACE) with Cisplation and Lipiodol in patients hepatocellular carcinoma (HCC) Child-Pugh A Cirrhosis.
Abstract Gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) is a paramagnetic hepatobiliary magnetic resonance (MR) contrast agent. Due to its OATP1B1/B3-dependent hepatocyte-specific uptake and properties increasing evidence has emerged suggest that Gd-EOB-DTPA-enhanced MRI can be potentially used for evaluation of liver function. In this paper we compare the diagnostic performance relaxometry-based commonly signal-intensity (SI)-based indices, including hepatocellular...
Thrombosis inside the membrane oxygenator (MO) is a critical complication during venovenous extracorporeal oxygenation (ECMO). The aim of this study was to prove if thrombotic clots manifest within MO when D-dimer levels are elevated over long-term period. Heparin-coated polymethylpentene MOs (n = 13) were exchanged due high plasma levels. Clot volume calculated using multidetector computed tomography (MDCT). Coagulation parameters and function analyzed before after exchange. Before...
Gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) is a hepatocyte-specific MRI contrast agent. Because the hepatic uptake of Gd-EOB-DTPA depends on integrity hepatocyte mass, this can be quantified to assess liver function. We report relationship between extent and degree fibrosis. T1-weighted volume-interpolated breath-hold examination (VIBE) sequences with fat suppression were acquired before 20 minutes after injection. Strong correlations characteristics relative...
Abstract Aim of this retrospective analysis was to evaluate the survival times after percutaneous irreversible electroporation (IRE) in inoperable liver tumors not amenable thermal ablation. 71 patients (14 females, 57 males, median age 63.5 ± 10.8 years) with 103 were treated 83 interventions using IRE (NanoKnife ® system). The tumor short-axis diameter 1.9 cm (minimum 0.4 cm, maximum 4.5 cm). 35 had primary and 36 metastases. Kaplan-Meier method employed calculate rates, different groups...
In the hands of experienced examiners, contrast enhanced sonography (CEUS) offers possibility to analyze dynamic microcirculatory disturbances in real time dynamically without any risk for kidneys and thyroid gland even severe progressing
Background and Aims: Intermediate stage hepatocellular carcinoma (HCC) can be treated by transarterial chemoembolization (TACE). However, there appear to side effects, such as induction of proangiogenic factors, e.g. vascular endothelial growth factor (VEGF), which have been shown associated with a poor prognosis. This prospective study was designed compare serum VEGF level response after TACE different embolic agents in patients HCC. Methods: Patients were assigned one three regimens:...
BACKGROUND: The continuous development of ultrasound techniques increasingly enables better description and visualization unclear lesions. New systems must be evaluated with regard to all these diagnostic possibilities. METHODS: A multifrequency C1-7 convex probe (SC7-1M) the new high-end system Resona A20 Series was used. Modern technologies, including HiFR CEUS, SR CEUS multimodal tissue imaging shear wave elastography (SWE), fat evaluation viscosity measurements (M-Ref) were applied....
Using a dual-wavelength (670 nm, 785 nm) time-domain scanning instrument we have recorded optical mammograms of 93 patients suspected having breast cancer which was subsequently assessed histologically. Among 65 histologically confirmed carcinomas, 54 were detectable in at least one two each tumour-bearing craniocaudal and mediolateral projection. Optical based on photon counts selected time windows measured distributions times flight photons. properties 50 carcinomas investigated both...
Using a triple wavelength (670 nm, 785 843/884 nm) scanning laser-pulse mammograph we recorded craniocaudal and mediolateral projection optical mammograms of 154 patients, suspected having breast cancer. From distributions times flight photons at typically 1000–2000 scan positions, were derived displaying (inverse) photon counts in selected time windows, absorption reduced scattering coefficients or total haemoglobin concentration blood oxygen saturation. Optical analysed by comparing them...
Background Mass-forming focal pancreatitis (FP) may mimic pancreatic cancer (PC) on magnetic resonance (MR) imaging, and the preoperative differential diagnosis is often difficult. Recently, usefulness of diffusion-weighted imaging (DWI) in has been reported several studies. Purpose To investigate if apparent diffusion coefficient (ADC) measurements based echo-planar (DW-EPI) distinguish between normal pancreas parenchyma, mass-forming pancreatitis, carcinoma. Material Methods MRI was...
Pulmonary hypertension (PH) often leads to dilatation of the pulmonary artery (PA), which can be measured on chest computed tomography (CT). While predictive capability PA is useful distinguish PH (mean pressure ≥25 mmHg) from normal ≤ 20 mmHg), CT characteristics borderline 21–24 have not been described. We aimed investigate whether patients with already show and assess diagnostic accuracy for diagnosis. Between April 2003 September 2008, consecutive symptomatic a mean below 25 mmHg right...