Takashi Ikeya
- Gastrointestinal disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Diverticular Disease and Complications
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Pancreatic and Hepatic Oncology Research
- Helicobacter pylori-related gastroenterology studies
- Pancreatitis Pathology and Treatment
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Neuroendocrine Tumor Research Advances
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- Foreign Body Medical Cases
- Colorectal Cancer Surgical Treatments
- Tracheal and airway disorders
- Gallbladder and Bile Duct Disorders
- Intestinal and Peritoneal Adhesions
- Alcohol Consumption and Health Effects
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism
- Medical Imaging and Pathology Studies
St. Luke's International Hospital
2015-2024
St. Luke's International University
2021-2024
American Society for Gastrointestinal Endoscopy
2022
University Gastroenterology
2020
Jichi Medical University
2009-2011
Jichi Medical University Saitama Medical Center
2009-2011
INTRODUCTION: The bleeding source of hematochezia is unknown without performing colonoscopy. We sought to identify whether colonoscopy a risk-stratifying tool etiology and predict outcomes presenting symptoms can differentiate the etiologies in patients with hematochezia. METHODS: This multicenter retrospective cohort study conducted at 49 hospitals across Japan analyzed 10,342 admitted for outpatient-onset acute RESULTS: Patients were mostly elderly population, 29.5% had hemodynamic...
Abstract Background Direct and indirect clipping treatments are used worldwide to treat colonic diverticular bleeding (CDB), but their effectiveness has not been examined in multicenter studies with more than 100 cases. Objective We sought determine the short‐ long‐term of direct versus for CDB a nationwide cohort. Methods studied 1041 patients who underwent ( n = 360) or 681) at 49 hospitals across Japan (CODE BLUE‐J Study). Results Multivariate analysis adjusted age, sex, important...
Background The rebleeding risks and outcomes of endoscopic treatment for acute lower gastrointestinal bleeding (ALGIB) may differ depending on the location, type, etiology stigmata recent hemorrhage (SRH) but have yet to be fully investigated. We aimed identify high risk SRH propose an optimal strategy. Methods retrospectively analyzed 2699 ALGIB patients with at 49 hospitals (CODE BLUE-J Study), whom 88.6 % received treatment. Results 30-day rates untreated significantly differed among...
<b>Background and study aims:</b> Long-term outcomes of endoscopic band ligation (EBL) for colonic diverticular hemorrhage have not been reported to date. The aim this was determine the long-term EBL retrospectively compare them with those clipping (EC) in treatment hemorrhage. <b>Patients methods: </b>The included patients who were treated or EC from January 2004 November 2014 followed up more than 1 year (61 group 39 group). Time-to-event analysis rebleeding performed Kaplan-Meier method....
Endoscopic band ligation (EBL) has been used for hemostasis of colonic diverticular hemorrhage. However, early rebleeding (< 30 days after EBL) reported in some cases. The aim this study was to elucidate risk factors EBL treatment hemorrhage.A total 101 patients with definite hemorrhage treated using from June 2009 October 2014 were included the retrospective cohort and divided into non-rebleeding groups, depending on presence or absence rebleeding. Patients' ages, comorbid diseases,...
Currently, large, nationwide, long-term follow-up data on acute lower gastrointestinal bleeding (ALGIB) are scarce. We investigated risks of recurrence after hospital discharge for ALGIB using a large multicenter dataset.
The study aimed to identify prognostic factors for patients with acute lower gastrointestinal bleeding and develop a high-accuracy prediction tool. analysis included 8254 cases of hematochezia who were admitted urgently based on the judgment emergency physicians or gastroenterology consultants (from CODE BLUE J-study). Patients randomly assigned derivation cohort validation in 2:1 ratio using random number table. Assuming that present at time admission are involved mortality within 30 days...
Background and AimsWe aimed to determine the optimal timing of colonoscopy factors that benefit patients who undergo early for acute lower GI bleeding.MethodsWe identified 10,342 with hematochezia (CODE BLUE-J study) admitted 49 hospitals in Japan. Of these, 6270 underwent a within 120 hours were included this study. The inverse probability treatment weighting method was used adjust baseline characteristics among (≤24 hours, n = 4133), elective (24-48 1137), late (48-120 1000) colonoscopy....
Endoscopic band ligation (EBL) has been used to achieve hemostasis in patients with colonic diverticular bleeding. The safety and effectiveness of EBL when performed by non-expert endoscopists have not sufficiently verified. This study aimed elucidate the feasibility technique considering as a standard treatment for bleeding.A retrospective cohort was conducted tertiary referral center Tokyo, Japan, between June 2009 October 2014. A total 95 treated were included divided into two groups...
Ligation therapy, including endoscopic detachable snare ligation (EDSL) and band (EBL), has emerged as an treatment for colonic diverticular bleeding (CDB); its comparative effectiveness risk of recurrent remain unclear, however. Our goal was to compare the outcomes EDSL EBL in treating CDB identify factors after therapy.We reviewed data 518 patients with who underwent (n = 77) or 441) a multicenter cohort study named Colonic Diverticular Bleeding Leaders Update Evidence From Multicenter...
<b><i>Background:</i></b> Oesophageal cancer comprises 2 different histological variants: oesophageal squamous-cell carcinoma (ESCC) and adenocarcinoma (EAC). While there are multiple therapeutic options for both types, patients with advanced or metastatic still suffer from poor prognosis. <b><i>Aims:</i></b> The study aimed to examine the association between risk of medications estimate chemopreventive effects commonly used drugs....
To investigate the safety and efficacy of endoscopic band ligation (EBL) for bleeding lesions in small bowel.This is a retrospective study evaluating EBL six consecutive patients (three males, three females, 46-86 years age) treated between May 2009 February 2014: duodenal vascular ectasia; 1, jejunal diverticulum; ileal Dieulafoy's lesion; 1 diverticula; 3. The success initial hemostasis was evaluated, were observed early rebleeding (within 30 d after EBL), complications such as perforation...
This study was designed to determine whether non-alcoholic fatty liver disease (NAFLD), with or without metabolic syndrome (MetS), is a risk factor for cancer development.We conducted retrospective longitudinal at the Center Preventive Medicine, St. Luke's International Hospital. Among all participants who underwent health checkup between 2005 and 2019, development tendencies were compared those diagnosed NAFLD not. Further evaluation among NAFLD-diagnosed versus MetS in same manner. Those...
Background/Aims In Asia, right-sided diverticular bleeding is more common than that of the left side. It often causes massive and difficulties in identifying stigmata recent hemorrhage (SRH) colonic (CDB). This case series demonstrates efficacy gel immersion method using OS-1 Jelly (Otsuka Pharmaceuticals Factory, Tokushima, Japan) patients with CDB. Methods retrospective analyzed data CDB who underwent from April 2016 to February 2020 at St. Luke's International Hospital, Japan. All...
Abstract Background The value of endoscopy for acute lower GI bleeding (ALGIB) remains unclear, given few large cohort studies. We aim to provide detailed clinical data ALGIB management and identify patients at risk adverse outcomes based on endoscopic diagnosis. Methods conducted a multicenter, retrospective study, named CODE BLUE J-Study, in 49 hospitals throughout Japan studied 10,342 cases admitted outpatient-onset hematochezia. Results Cases were mostly elderly, with 29.5% hemodynamic...
Metachronous gastric cancer often occurs after endoscopic resection. Appropriate management, including chemoprevention, is required the procedure. This study was performed to evaluate association between medication use and incidence of metachronous multicenter retrospective cohort conducted with data from nine hospital databases on patients who underwent resection for 2014 2019. The primary outcome cancer. We evaluated associations occurrence clinical factors. Hazard ratios were adjusted by...
Stigmata of recent hemorrhage (SRH) directly indicate a need for endoscopic therapy in acute lower gastrointestinal bleeding (LGIB). Colonoscopy would be prioritized patients with highly suspected SRH, but the predictors colonic SRH remain unclear. We aimed to construct predictive model efficient detection using nationwide cohort.We retrospectively analyzed 8360 admitted through hospital emergency departments LGIB CODE BLUE-J Study (49 hospitals throughout Japan). All underwent inpatient...
Abstract Background and Aim While short long attachment caps are available for colonoscopy, it is unclear which type more appropriate stigmata of recent hemorrhage (SRH) identification in acute hematochezia. This study aimed to compare the performance versus hematochezia diagnoses outcomes. Methods We selected 6460 patients who underwent colonoscopy with from 10 342 cases CODE BLUE‐J study. performed propensity score matching (PSM) balance baseline characteristics between cap users. Then,...
Abstract Background and Aims The identification of stigmata recent hemorrhage (SRH) in colonic diverticular bleeding (CDB) enables an endoscopic treatment can improve the clinical outcome. However, SRH rate remains low. This study aims to investigate whether NOBLADS Strate scoring systems are useful for predicting CDB pre‐procedurally via colonoscopy. Methods In this single‐center retrospective observational study, 302 patients who experienced their first episode from April 2008 March 2018...