A5003265664- Tuberculosis Research and Epidemiology
- International Arbitration and Investment Law
- Labor Movements and Unions
- World Trade Organization Law
- Global trade, sustainability, and social impact
- Mycobacterium research and diagnosis
- International Labor and Employment Law
- Corporate Law and Human Rights
- Antibiotic Resistance in Bacteria
- Environmental and Social Impact Assessments
- Cardiac Valve Diseases and Treatments
- Global trade and economics
- Human Rights and Development
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Tracheal and airway disorders
- Intellectual Property and Patents
- Antimicrobial Peptides and Activities
- Social Policy and Reform Studies
- Asian Industrial and Economic Development
- Infectious Diseases and Mycology
- Insect and Pesticide Research
- Carbohydrate Chemistry and Synthesis
- Regulation and Compliance Studies
Westmead Hospital
2025
Aston University
2018-2024
Duke University
1996-2023
Thomas Jefferson University
2021
University of Warwick
2010-2019
Duke Medical Center
1998-2019
Queen Mary University of London
2019
University of Sussex
2019
Coventry (United Kingdom)
2019
University of Manchester
2018
Randomized data comparing outcomes of transcatheter aortic valve replacement (TAVR) with surgery in low–surgical risk patients at time points beyond 2 years is limited. This presents an unknown for physicians striving to educate as part a shared decision-making process. The authors evaluated 3-year clinical and echocardiographic from the Evolut Low Risk trial. Low-risk were randomized TAVR self-expanding, supra-annular or surgery. primary endpoint all-cause mortality disabling stroke several...
Abstract The EU has established a new architecture of international labour standards governance within the Trade and Sustainable Development (TSD) chapters its Free Agreements (FTAs). To examine operationalization this framework, we draw upon 121 interviews undertaken with key informants in three FTAs signed Caribbean, South Korea Moldova. We engage wider debates over external projection power by showing how operational failings, including lack legal political prioritization TSD shortcomings...
Antimicrobial resistance is a global healthcare problem with dwindling arsenal of usable drugs. Tuberculosis, caused by Mycobacterium tuberculosis, requires long-term combination therapy and multi- totally drug resistant strains have emerged. This study reports the antibacterial activity cationic polymers against mycobacteria, which are distinguished from other Gram-positive bacteria their unique cell wall comprising covalently linked mycolic acid–arabinogalactan–peptidoglycan complex...
This article examines the relations between workplace and local labor regimes, global production networks (GPNs), state-led creation of expanded markets as spaces capitalist regulation through trade policy. Through an examination ways in which regimes are constituted a result articulation social lead-firm pressure GPNs, limits provisions European Union policy seeking to ameliorate worst consequences liberalization economic integration on working conditions. The takes its empirical focus...
This article critically evaluates the current practice and future potential of human rights impact assessment (HRIA) as a tool measurement. The first explores origins purposes HRIAs claims made by commentators about what can achieve. It goes on to provide an overview existing in HRIA wide variety different fields including health, business, trade, child rights, development. then argues that poor practice, particularly among governmental business actors, highlights need for greater scrutiny...
ABSTRACT Mycobacterium tuberculosis , the etiological agent of (TB), has a unique cell envelope which accounts for its unusual low permeability and contributes to resistance against common antibiotics. The main structural elements wall consist cross-linked network peptidoglycan (PG) in some muramic acid residues are covalently attached complex polysaccharide, arabinogalactan (AG), via α- l -rhamnopyranose–(1→3)-α- d -GlcNAc-(1→P) linker unit. While molecular genetics associated with PG AG...
Abstract Infections caused by Mycobacterium abscessus are increasing in prevalence cystic fibrosis patients. This opportunistic pathogen′s intrinsic resistance to most antibiotics has perpetuated an urgent demand for new, more effective therapeutic interventions. Here we report a prospective advance the treatment of M. infection; susceptibility organism amoxicillin, repurposing β-lactamase inhibitor, relebactam, combination with front line drug imipenem. We establish multiple vitro methods...
The purpose of our study is to describe the radiologic findings adult patients presenting with congenital unilateral pulmonary vein atresia.Chest radiography in affected typically reveals a small hemithorax and ipsilateral artery as well septal thickening. CT shows, addition, ground-glass attenuation, absence connection left atrium, abundant mediastinal venous collateral vessels. MR imaging helpful further characterizing vascular abnormalities. Angiography may help confirm diagnosis.
The United Nations Special Representative of the Secretary-General on Business and Human Rights, Professor John Ruggie, has constructed a new international framework, which is set to become cornerstone for all action human rights business at level. principle due diligence (HRDD) central component corporate duty respect within that framework. This article argues Ruggie's HRDD contains majority core procedural elements reasonable impact assessment (HRIA) process should incorporate. It likely...
Abstract The European Union (EU) has concluded close to 50 bilateral free trade agreements (FTAs), with around 10 more under negotiation. EU FTAs now include “trade and sustainable development” chapters, which contain labour provisions based on a “promotional” rather than “conditional” approach. In the context of debate purpose efficacy trade–labour linkage, authors examine possibilities limitations these provisions, drawing attention lack research their effect “on ground”. To bridge this...
Multidetector computed tomography is useful for determining the appropriate transcatheter heart valve (THV) size in patients with severe aortic stenosis who are suboptimal surgical candidates. The relationship between adherence to recommended CoreValve sizing algorithm and clinical outcomes not known.We evaluated 1023 deemed high or extreme risk surgery treated THV. All underwent preprocedural multidetector tomography, scans were reviewed at a central analysis center using standardized...
Abstract The use of nanoparticles for targeted delivery therapeutic agents to sites injury or disease in the central nervous system (CNS) holds great promise. However, biodistribution following vivo administration is often unknown, and concerns have been raised regarding potential toxicity. Using poly(glycidyl methacrylate) (PGMA) coated with polyethylenimine (PEI) containing superparamagnetic iron oxide as a magnetic resonance imaging (MRI) contrast agent rhodamine B fluorophore, whole...
Abstract Labour standards provisions within the Trade and Sustainable Development (TSD) chapters of EU Free Agreements (FTAs) are presented as a key element EU's commitment to ‘value-based trade agenda’. But criticism TSD has led European Commission commit improving their implementation enforcement, creating critical juncture in evolution trade–labour linkage. This contribution synthesizes findings from academic studies that have examined effectiveness labour FTAs. It then considers reform...
Summary Dynamic carotid compression arising from a change in patient position is rare complication of goitre, with the potential for cerebral ischaemia and infarction. In this report, 37‐year‐old woman presented multi‐nodular goitre clinical features concerning transient ischaemia. The anaesthetic management neurological monitoring used to mitigate risk during thyroidectomy described literature surrounding explored.
Mycobacteria are a large family of over 100 species, most which do not cause diseases in humans. The majority the mycobacterial species referred to as nontuberculous mycobacteria (NTM), meaning they causative agent tuberculous (TB) or leprosy, i.e. Mycobacterium complex and leprae, respectively. latter group is undoubtedly infamous, with TB infecting an estimated 10 million people causing 1.2 deaths 2017 alone (1). leprosy also differ from NTM that only transmitted person have no...
This article will examine key issues associated with conducting human rights impact assessments (HRIAs) of international trade agreements. It records the widespread calls for such HRIAs by relevant actors, but highlights fact that limited attempts have so far been made to explore important concerning their design and intrinsic value. therefore poses some questions which need be considered in development appropriate methodologies explores extent these methodological can best appropriately...
Abstract This article explores the interrelationship between global production networks (GPNs) and free trade agreements (FTAs) in South Korean auto industry its employment relations. It focuses on network of Hyundai Motor Group (HMG) — third biggest automobile manufacturer world FTA EU Korea. was first EU's ‘new generation’ FTAs, which among other things contained provisions designed to protect promote labour standards. The article's argument is twofold. First, that HMG's Korea's political...