- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Acute Ischemic Stroke Management
- Cardiac Structural Anomalies and Repair
- Cardiovascular and Diving-Related Complications
- Cardiovascular Effects of Exercise
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Congenital Heart Disease Studies
- Urological Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Kidney Stones and Urolithiasis Treatments
- Heart Failure Treatment and Management
- Ureteral procedures and complications
Swami Rama Himalayan University
2016-2024
Geisinger Medical Center
2016-2024
Institute of Medical Sciences
2018-2024
Himalayan Institute of Yoga Science and Philosophy
2024
Jawaharlal Nehru Medical College Hospital
2024
Aligarh Muslim University
2024
Ruby Hall Clinic
2021
Valley Hospital
2020
Shiv Nadar University
2020
Geisinger Wyoming Valley Medical Center
2020
Randomized data comparing outcomes of transcatheter aortic valve replacement (TAVR) with surgery in low–surgical risk patients at time points beyond 2 years is limited. This presents an unknown for physicians striving to educate as part a shared decision-making process. The authors evaluated 3-year clinical and echocardiographic from the Evolut Low Risk trial. Low-risk were randomized TAVR self-expanding, supra-annular or surgery. primary endpoint all-cause mortality disabling stroke several...
Background— We sought to assess the utility of left ventricular global longitudinal strain (LV-GLS) in predicting mortality moderate severe and paradoxical aortic stenosis (AS) patients with preserved ejection fraction. Methods Results— studied 395 AS (70±14 years, 57% men) valve area <1.3 cm 2 evaluated between January June 2008 (excluding other disease LV fraction <50%). Clinical echocardiographic data were recorded. LV-GLS was analyzed using Velocity Vector Imaging. classified as...
Background— Prior studies of stroke and transient ischemic attack (TIA) after transcatheter aortic valve replacement (TAVR) are limited by reporting follow-up variability. This is a comprehensive analysis time-related incidence, risk factors, outcomes these events. Methods Results— From April 2007 to February 2012, 2621 patients, aged 84±7.2 years, underwent transfemoral (TF; 1521) or transapical (TA; 1100) TAVR in the PARTNER trial (Placement Aortic Transcatheter Valves; as-treated),...
Background— The long-term outcomes of transcatheter aortic valve replacement (TAVR) in inoperable patients with severe stenosis remain unknown. Methods and Results— In the Placement Aortic Transcatheter Valves (PARTNER) study, 358 were randomly assigned to TAVR or standard therapy. We report 3-year on these patients, pooled for all (n=449) PARTNER, as well, including randomized portion continued access study (n=91). mortality rate therapy groups was 54.1% 80.9%, respectively ( P <0.001;...
We assessed the role of lead and cadmium as partial mediators between smoking composite cardiovascular cerebrovascular disease (CCVD). also studied association urinary heavy metals CCVD. Pooled data from NHANES 1999-2006 were examined. Cardiovascular was determined using a standardized questionnaire asking about history stroke, angina, heart attack, coronary artery disease, congestive failure. Increasing serum levels associated with increasing prevalence CCVD (P-trend: .03). Adjusted...
Preoperative management of patients with aortic stenosis (AS) who need noncardiac surgery (NCS) remains controversial. We sought to determine the impact AS on postoperative outcomes after NCS.Patients undergoing NCS moderate (valve area: 1.0-1.5 cm(2)) or severe <1.0 were identified using surgical and echocardiographic databases. Using propensity score analysis, we obtained 4 matched control without for each patient NCS. The matching used 6 revised cardiac risk index criteria, in addition...
Background— With the availability of transcatheter aortic valve replacement, management coronary artery disease in patients with severe stenosis (AS) is posing challenges. Outcomes percutaneous intervention (PCI) AS and remain unknown. We sought to compare short-term outcomes PCI without AS. Methods Results— From our database, we identified 254 who underwent between 1998 2008. Using propensity matching, found 508 same period. The primary end point 30-day mortality after was similar (4.3% [11...
Background We aimed to assess trends in hospitalization, outcomes, and resource utilization among patients admitted with adult congenital heart disease ( ACHD ). Methods Results used the 2003–2012 US Nationwide Inpatient Sample for this study. All admissions an were identified using standard ICD codes. Resource was assessed length of stay, invasive procedure utilization, cost hospitalization. There a significant increase number both simple (101%) as well complex (53%)–related across...
Background— The decision-making role of exercise echocardiography in the surgical timing for aortic regurgitation remains a matter debate because limited data on its link with outcome. aim this study was to assess echocardiographic measurements at rest and during as predictors valve surgery asymptomatic regurgitation. Methods Results— Comprehensive resting performed 159 consecutive patients (50±15 years; 80% male) isolated moderately severe preserved left ventricular (LV) function (LV...
Delayed hyperenhancement (DHE) of the pericardium usually represents ongoing inflammation and may identify patients with constrictive pericarditis that will improve anti-inflammatory therapy. However, a quantitative assessment pericardial DHE has not been performed, hierarchical relationship among clinical factors, inflammatory markers, is unknown.We identified 41 consecutive who had cardiovascular magnetic resonance study prior to initiation medications. Pericardial was quantified on...
Cardiorespiratory fitness is an important predictor of cardiovascular morbidity and mortality. Both red cell distribution width (RDW) inflammatory markers like C-reactive protein (CRP) have been shown to predict adverse outcomes in patients with heart disease. We utilized pooled data from NHANES 1999–2004 assess cardiorespiratory healthy adults 12–49 years old using submaximal exercise. The primary outcome was the estimated maximal oxygen uptake (VO2max). Low defined as VO2max < 20th...