- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Cardiac Health and Mental Health
- COVID-19 Clinical Research Studies
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- Acute Ischemic Stroke Management
- Cardiac Structural Anomalies and Repair
- Peripheral Artery Disease Management
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Disease and Adiposity
- Cardiac Arrhythmias and Treatments
- Ultrasound in Clinical Applications
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Blood Pressure and Hypertension Studies
- Congenital Heart Disease Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac pacing and defibrillation studies
Icahn School of Medicine at Mount Sinai
2017-2023
St. Luke's Hospital
2020
St. Luke's Hospital
2017-2020
Mount Sinai Hospital
2018-2020
Command Hospital
2020
Mount Sinai Hospital
2020
INHS Asvini
2012-2019
St. Luke's-Roosevelt Hospital Center
2019
Geisinger Medical Center
2017
Cleveland Clinic
2015-2016
Congenital sodium diarrhea (CSD) refers to an intractable of intrauterine onset with high fecal loss. CSD is clinically and genetically heterogeneous. Syndromic caused by SPINT2 mutations. While we recently described four cases the non-syndromic form that were dominant activating mutations in intestinal receptor guanylate cyclase C (GC-C), genetic cause for majority still unknown. Therefore, aimed determine non-GC-C 18 patients from 16 unrelated families applying whole-exome sequencing...
Background We aimed to assess trends in hospitalization, outcomes, and resource utilization among patients admitted with adult congenital heart disease ( ACHD ). Methods Results used the 2003–2012 US Nationwide Inpatient Sample for this study. All admissions an were identified using standard ICD codes. Resource was assessed length of stay, invasive procedure utilization, cost hospitalization. There a significant increase number both simple (101%) as well complex (53%)–related across...
ABSTRACT Background We assessed trends in incidence, in‐hospital mortality, and admission among patients with adult congenital heart disease ( ACHD ) presenting to the emergency department ED from 2006 2012. Hypothesis There is a considerable burden of US EDs. Methods used 2006–2012 Nationwide Emergency Department Sample. All visits were identified using standard International Classification Diseases, Ninth Edition, Clinical Modification codes. Results The number simple (40.6%) as well...
COVID-19 affects multiple organs. Clinical data from the Mount Sinai Health System show that substantial numbers of patients without prior heart disease develop cardiac dysfunction. How is not known. We integrated cell biological and physiological analyses human cardiomyocytes differentiated induced pluripotent stem cells (hiPSCs) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in presence interleukins (ILs) clinical findings related to laboratory values identify...
Abstract Background Despite improvements in acute care and survival after non‐ST‐elevation coronary syndrome (NSTE‐ACS) hospitalization, early readmissions remain common, have significant clinical financial impact. Objectives Determine the predictors etiologies of 30‐day NSTE‐ACS. Method The study cohort was derived from National Readmission Database 2014 identifying patients with a primary diagnosis NSTE‐ACS using ICD9 code. Results We identified total 300,269 admitted NSTE‐ACS; 13.4% were...
Obesity is significantly associated with uncontrolled blood pressure and resistant hypertension (RH). There are limited studies on the prevalence determinants of RH in patients higher body mass index (BMI) values. Since guidelines changed 2017, has become unknown now subject to be estimated by further studies. We conducted a cross-sectional study an urban Federally Qualified Health Center New York City aiming estimate high-risk overweight obese based new definition, BP threshold ≥130/80 mm...
Background: Treatment of left ventricular outflow tract (LVOT) obstruction involves a combination negative inotropic agents. However, these therapies have limitations which may result in insufficient control symptoms, leading to more invasive options such as surgical septal myectomy or alcohol ablation. Mavacamten, cardiac myosin inhibitor, is currently approved for the treatment patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM). We present case patient treated...
COVID-19 affects multiple organs. Clinical data from the Mount Sinai Health System shows that substantial numbers of patients without prior heart disease develop cardiac dysfunction. How is not known. We integrate cell biological and physiological analyses human cardiomyocytes differentiated induced pluripotent stem cells (hiPSCs) infected with SARS-CoV-2 in presence interleukins, clinical findings, to investigate plausible mechanisms patients. hiPSC-derived cardiomyocytes, healthy subjects,...