Karan Sud

ORCID: 0000-0002-6122-5655
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About
Contact & Profiles
Research Areas
  • Heart Failure Treatment and Management
  • Acute Myocardial Infarction Research
  • Cardiac Valve Diseases and Treatments
  • Cardiac Health and Mental Health
  • COVID-19 Clinical Research Studies
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Function and Risk Factors
  • Mechanical Circulatory Support Devices
  • Cardiac Imaging and Diagnostics
  • SARS-CoV-2 and COVID-19 Research
  • Acute Ischemic Stroke Management
  • Cardiac Structural Anomalies and Repair
  • Peripheral Artery Disease Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Disease and Adiposity
  • Cardiac Arrhythmias and Treatments
  • Ultrasound in Clinical Applications
  • Long-Term Effects of COVID-19
  • Respiratory Support and Mechanisms
  • Cardiac Arrest and Resuscitation
  • Blood Pressure and Hypertension Studies
  • Congenital Heart Disease Studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cardiac pacing and defibrillation studies

Icahn School of Medicine at Mount Sinai
2017-2023

St. Luke's Hospital
2020

St. Luke's Hospital
2017-2020

Mount Sinai Hospital
2018-2020

Command Hospital
2020

Mount Sinai Hospital
2020

INHS Asvini
2012-2019

St. Luke's-Roosevelt Hospital Center
2019

Geisinger Medical Center
2017

Cleveland Clinic
2015-2016

Congenital sodium diarrhea (CSD) refers to an intractable of intrauterine onset with high fecal loss. CSD is clinically and genetically heterogeneous. Syndromic caused by SPINT2 mutations. While we recently described four cases the non-syndromic form that were dominant activating mutations in intestinal receptor guanylate cyclase C (GC-C), genetic cause for majority still unknown. Therefore, aimed determine non-GC-C 18 patients from 16 unrelated families applying whole-exome sequencing...

10.1093/hmg/ddv367 article EN Human Molecular Genetics 2015-09-10

Background We aimed to assess trends in hospitalization, outcomes, and resource utilization among patients admitted with adult congenital heart disease ( ACHD ). Methods Results used the 2003–2012 US Nationwide Inpatient Sample for this study. All admissions an were identified using standard ICD codes. Resource was assessed length of stay, invasive procedure utilization, cost hospitalization. There a significant increase number both simple (101%) as well complex (53%)–related across...

10.1161/jaha.115.002330 article EN cc-by-nc-nd Journal of the American Heart Association 2016-01-13

10.1016/j.jacc.2017.02.040 article EN publisher-specific-oa Journal of the American College of Cardiology 2017-03-06

ABSTRACT Background We assessed trends in incidence, in‐hospital mortality, and admission among patients with adult congenital heart disease ( ACHD ) presenting to the emergency department ED from 2006 2012. Hypothesis There is a considerable burden of US EDs. Methods used 2006–2012 Nationwide Emergency Department Sample. All visits were identified using standard International Classification Diseases, Ninth Edition, Clinical Modification codes. Results The number simple (40.6%) as well...

10.1002/clc.22541 article EN Clinical Cardiology 2016-04-15

COVID-19 affects multiple organs. Clinical data from the Mount Sinai Health System show that substantial numbers of patients without prior heart disease develop cardiac dysfunction. How is not known. We integrated cell biological and physiological analyses human cardiomyocytes differentiated induced pluripotent stem cells (hiPSCs) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in presence interleukins (ILs) clinical findings related to laboratory values identify...

10.1128/jvi.01063-21 article EN cc-by Journal of Virology 2021-10-20

Abstract Background Despite improvements in acute care and survival after non‐ST‐elevation coronary syndrome (NSTE‐ACS) hospitalization, early readmissions remain common, have significant clinical financial impact. Objectives Determine the predictors etiologies of 30‐day NSTE‐ACS. Method The study cohort was derived from National Readmission Database 2014 identifying patients with a primary diagnosis NSTE‐ACS using ICD9 code. Results We identified total 300,269 admitted NSTE‐ACS; 13.4% were...

10.1002/ccd.27838 article EN Catheterization and Cardiovascular Interventions 2018-10-02

Obesity is significantly associated with uncontrolled blood pressure and resistant hypertension (RH). There are limited studies on the prevalence determinants of RH in patients higher body mass index (BMI) values. Since guidelines changed 2017, has become unknown now subject to be estimated by further studies. We conducted a cross-sectional study an urban Federally Qualified Health Center New York City aiming estimate high-risk overweight obese based new definition, BP threshold ≥130/80 mm...

10.1111/jch.13666 article EN Journal of Clinical Hypertension 2019-08-26

Background: Treatment of left ventricular outflow tract (LVOT) obstruction involves a combination negative inotropic agents. However, these therapies have limitations which may result in insufficient control symptoms, leading to more invasive options such as surgical septal myectomy or alcohol ablation. Mavacamten, cardiac myosin inhibitor, is currently approved for the treatment patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM). We present case patient treated...

10.1161/circ.150.suppl_1.4138268 article EN Circulation 2024-11-12

COVID-19 affects multiple organs. Clinical data from the Mount Sinai Health System shows that substantial numbers of patients without prior heart disease develop cardiac dysfunction. How is not known. We integrate cell biological and physiological analyses human cardiomyocytes differentiated induced pluripotent stem cells (hiPSCs) infected with SARS-CoV-2 in presence interleukins, clinical findings, to investigate plausible mechanisms patients. hiPSC-derived cardiomyocytes, healthy subjects,...

10.1101/2020.11.10.20229294 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-11-13
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