A Róger

ORCID: 0000-0003-4872-3171
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About
Contact & Profiles
Research Areas
  • RNA regulation and disease
  • Neurological diseases and metabolism
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Aging, Elder Care, and Social Issues
  • Nutrition and Health in Aging
  • Health, Medicine and Society
  • Neuropeptides and Animal Physiology
  • Drug Transport and Resistance Mechanisms
  • Pediatric Hepatobiliary Diseases and Treatments
  • Brain Metastases and Treatment
  • Plant-based Medicinal Research
  • Clinical Nutrition and Gastroenterology
  • Mitochondrial Function and Pathology
  • Biliary and Gastrointestinal Fistulas
  • Antibiotic Use and Resistance
  • Pain Mechanisms and Treatments
  • Sleep and Wakefulness Research
  • Animal Nutrition and Physiology
  • Cutaneous Melanoma Detection and Management
  • Neuroscience and Neuropharmacology Research
  • Thyroid Disorders and Treatments
  • Social Policies and Family
  • Nonmelanoma Skin Cancer Studies
  • Mycotoxins in Agriculture and Food

Centre d’Immunologie de Marseille-Luminy
2021-2024

Inserm
2022-2024

Centre National de la Recherche Scientifique
2022-2024

Aix-Marseille Université
2022-2024

Queen's University
2024

Institut de Neurophysiopathologie
2022

Centre des Sciences du Goût et de l'Alimentation
2019-2021

Université de Bourgogne
2019-2021

Université Bourgogne Franche-Comté
2019-2021

École Supérieure d'Agriculture
2020

Abstract Host protection against cutaneous herpes simplex virus 1 (HSV-1) infection relies on the induction of a robust adaptive immune response. Here, we show that Nav 1.8 + sensory neurons, which are involved in pain perception, control magnitude CD8 T cell priming and expansion HSV-1-infected mice. The ablation -expressing neurons is associated with extensive skin lesions characterized by enhanced inflammatory cytokine chemokine production. Mechanistically, required for downregulation...

10.1038/s41467-021-22841-6 article EN cc-by Nature Communications 2021-05-18

Evolution has created complex mechanisms to sense environmental danger and protect tissues, with the nervous immune systems playing pivotal roles. These work together, coordinating local systemic reflexes restore homeostasis in response tissue injury infection. By sharing receptors ligands, they influence pathogenesis of various diseases. Recently, a less-explored aspect neuroimmune communication emerged: release neuropeptides from cells cytokines/chemokines sensory neurons. This article...

10.1016/j.jaci.2024.02.006 article EN cc-by-nc-nd Journal of Allergy and Clinical Immunology 2024-02-17

Josas (/-'f <tKce) Résumé Une nouvelle technique, dite de fistulation iléo-colique post-valvulaire, permettant collecter les digesta tels qu'ils sont normalement émis vers le gros intestin, est décrite (fig. 2 ) et testée comparativement à la technique conventionnelle ileo-caecale.Neuf porcs mâles castrés race Large White, d'un poids vif compris entre 47 6 4 kg, ont reçu un seul repas quotidien aliment semi-synthétique base d'amidon purifié (maïs ou blé, 70 p.l oo M.S.) farine poisson ( 1...

10.1051/animres:19800205 article FR Annales de Zootechnie 1980-01-01

colique, fait que la digestibilité fécale peut conduire à des estimations erronées de leur disponibilité.Au total, apparente iléale AA constitue une bonne image réelle pour certains régimes.Mais sa validité reste tributaire variabilité apports endogènes et difficulté évaluation.

10.1051/animres:19820306 article FR Annales de Zootechnie 1982-01-01

Large portion sizes can make children overeat, alter their self-regulation abilities and induce weight gain. However, little is known about how parents determine for children. Using semi-structured interviews with 5 fathers 32 mothers of pre-schoolers, this study examined French parents’ food portioning practices. The division responsibility between parent child in deciding was explored, as well the influencing factors possible sources information. Parents described a wide range For most,...

10.3390/nu13082769 article EN Nutrients 2021-08-12

The tumor microenvironment is a dynamic network of stromal, cancer, and immune cells that interact compete for resources. We have previously identified the Vanin1 pathway as suppressor sarcoma development via vitamin B5 coenzyme A regeneration. Using an aggressive cell line lacks Vnn1 expression, we showed administration pantethine, precursor, attenuates growth in immunocompetent but not nude mice. Pantethine boosts antitumor immunity, including polarization myeloid dendritic towards...

10.26508/lsa.202302200 article EN cc-by Life Science Alliance 2023-10-13

Le débit de la sécrétion biliaire, collectée par fistulation l'about hépatique du cholédoque sectionné, a été mesuré chez 14 porcs race Large White pesant 57 à 6 3 kg, bile étant réin- troduite constant tout au long nycthémère soit dans intestinal cholédoque, irriguant ainsi le trajet sphinctérien, directement lumière duodénale.La variabilité biliaire d'un jour l'autre pour un même animal, et individu apparaît comme relativement importante sans qu'une relation régulière puisse être établie...

10.1051/animres:19770411 article FR Annales de Zootechnie 1977-01-01

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a member the TNF ligand family involved in various diseases including brain inflammatory pathologies such as multiple sclerosis. It has been demonstrated that TWEAK can induce cerebrovascular permeability an vitro model blood-brain barrier. The molecular mechanisms playing role versus TNFα signaling on cerebral microvascular endothelial cells are not well defined. Therefore, we aimed to identify gene expression changes cultures...

10.3390/genes13101714 article EN Genes 2022-09-24
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