- Pesticide and Herbicide Environmental Studies
- Microbial bioremediation and biosurfactants
- Microbial Community Ecology and Physiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Genomics and Phylogenetic Studies
- Microbial Metabolic Engineering and Bioproduction
- Chromium effects and bioremediation
- Environmental Toxicology and Ecotoxicology
- Legume Nitrogen Fixing Symbiosis
- Enzyme Catalysis and Immobilization
- Bacterial Genetics and Biotechnology
- Plant-Microbe Interactions and Immunity
- Wastewater Treatment and Nitrogen Removal
- Insect symbiosis and bacterial influences
- Microbial Fuel Cells and Bioremediation
- Microbial Natural Products and Biosynthesis
- Plant Disease Resistance and Genetics
- Mycorrhizal Fungi and Plant Interactions
- Plant Pathogens and Fungal Diseases
- Analytical chemistry methods development
- Pharmacogenetics and Drug Metabolism
- Gut microbiota and health
- Antibiotic Resistance in Bacteria
- Insect and Pesticide Research
- Toxic Organic Pollutants Impact
Nanjing Agricultural University
2016-2025
Ministry of Agriculture and Rural Affairs
2022-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Lanzhou University
2024
Zhejiang University of Technology
2023
Ministère de l'Agriculture et de la Souveraineté alimentaire
2017
Microbial communities are believed to outperform monocultures in the complete catabolism of organic pollutants via reduced metabolic burden and increased robustness environmental challenges; however, interaction mechanism functional microbiomes remains poorly understood. Here, three functionally differentiated activated sludge (S1: sulfamethoxazole (SMX); S2: phenyl part SMX ([phenyl]-SMX) with stable accumulation its heterocyclic product 3-amino-5-methylisoxazole (3A5MI); A: 3A5MI rather...
Abstract Background Soil microbiomes are considered a cornerstone of the next green revolution, and plant growth-promoting bacteria (PGPB) critical for microbiome engineering. However, taking plant-beneficial microorganisms from discovery to agricultural application remains challenging, as mechanisms underlying interactions between beneficial strains plants in native soils still largely unknown. Increasing numbers studies have indicated that introduced manipulate usually eliminated soils,...
Abstract Engineering natural microbiomes for biotechnological applications remains challenging, as metabolic interactions within are largely unknown, and practical principles tools microbiome engineering still lacking. Here, we present a combinatory top-down bottom-up framework to engineer the construction of function-enhanced synthetic microbiomes. We show that application herbicide herbicide-degrader inoculation drives convergent succession different toward functional (e.g., enhanced...
Abstract Arbuscular mycorrhizal fungi (AMF) affect multiple ecosystem functions and processes, the assemblages of which vary across ecosystems. However, influences environmental factors on AMF communities may shape these are still largely unknown. In this study, from roots rhizosphere soils Chenopodium ambrosioides in different natural were investigated. The root habitat showed significantly smaller numbers OTUs lower community richness compared to soil habitat. Most shared by same sampling...
Haloaromatic antimicrobial triclocarban (3,4,4′-trichlorocarbanilide, TCC) is a refractory contaminant which frequently detected in various aquatic and sediment environments globally. However, few TCC-degrading communities or pure cultures have been documented, functional enzymes involved TCC biodegradation hitherto not yet characterized. In this study, bacterial strain, Ochrobactrum sp. TCC-2, capable of degrading under both aerobic anaerobic conditions was isolated from sample. A novel...
Sphingomonads DC-6 and DC-2 degrade the chloroacetanilide herbicides alachlor, acetochlor, butachlor via N-dealkylation. In this study, we report a three-component Rieske non-heme iron oxygenase (RHO) system catalyzing N-dealkylation of these herbicides. The component gene cndA is located in transposable element that highly conserved two strains. CndA shares 24 to 42% amino acid sequence identities with components some RHOs catalyze N- or O-demethylation. Two putative [2Fe-2S] ferredoxin...
Phytopathogenic fungi threaten global food security but the ecological drivers of their diversity and biogeography remain unknown. Here, we construct analyse a atlas potential phytopathogenic from 20,312 samples across all continents major oceanic island regions, eleven land cover types, twelve habitat types. We show peak in mid-latitude contrast to latitudinal gradients observed aboveground organisms. Our study identifies climate as an important driver distribution fungi, our models suggest...
Abstract Ammonia-oxidizing archaea (AOA) are among the most ubiquitous and abundant on Earth, widely distributed in marine, terrestrial, geothermal ecosystems. However, genomic diversity, biogeography, evolutionary process of AOA populations subsurface environments vastly understudied compared to those marine soil systems. Here, we report a novel order Candidatus (Ca.) Nitrosomirales which forms sister lineage thermophilic Ca. Nitrosocaldales. Metagenomic 16S rRNA gene-read mapping...
Bacterial–fungal interaction (BFI) has significant implications for the health of host plants. While diffusible antibiotic metabolite-mediated competition in BFI been extensively characterized, impact intercellular contact remains largely elusive. Here, we demonstrate that is a prevalent mode between beneficial soil bacteria and pathogenic filamentous fungi. By generating antibiotics-deficient mutants two common bacteria, Lysobacter enzymogenes Pseudomonas fluorescens , show...
Dehalogenation is the key step in degradation of halogenated aromatics, while reductive dehalogenation originally thought to rarely occur aerobes. In this study, an aerobic strain Comamonas sp. 7D-2 was shown degrade brominated aromatic herbicide bromoxynil completely and release two equivalents bromides under conditions. The enzymes involved 4-carboxy-2-hydroxymuconate-6-semialdehyde, including nitrilase, dehalogenase (BhbA), 4-hydroxybenzoate 3-monooxygenase protocatechuate...
Bacillus subtilis is developed to be an attractive expression host produce both secreted and cytoplasmic proteins owing its prominent biological characteristics. Chromosomal integration a stable strategy while the level not ideal compared with plasmid expression. Thus, meet requirement of protein overexpression, promoter, as one key elements, important. It necessary obtain promoter for overproduction foreign from single copy cassette. The activity Pylb was further enhanced by optimizing −...
ABSTRACT Halophyte-based remediation emerges as a novel strategy for ameliorating saline soils, offering sustainable alternative to conventional leaching methods. While bioremediation is recognized its ability energize soil fertility and structure, the complex interplays among plant traits, functions, microbial diversity remain greatly unknown. Here, we conducted 5-year field experiment involving continuous cultivation of annual halophyte Suaeda salsa in soils explore their relationships...