A5101648021- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Mycobacterium research and diagnosis
- Pleural and Pulmonary Diseases
- Medical Imaging and Pathology Studies
- Lung Cancer Treatments and Mutations
- Tracheal and airway disorders
- Parasitic infections in humans and animals
- Lung Cancer Diagnosis and Treatment
- Asthma and respiratory diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pneumonia and Respiratory Infections
- Vascular Anomalies and Treatments
- Hematological disorders and diagnostics
- Immunodeficiency and Autoimmune Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sarcoidosis and Beryllium Toxicity Research
- Respiratory Support and Mechanisms
- Congenital Anomalies and Fetal Surgery
- Nosocomial Infections in ICU
- Cancer Genomics and Diagnostics
- Dysphagia Assessment and Management
- Emergency and Acute Care Studies
- Sinusitis and nasal conditions
University of Monastir
2025
Mohammed V University
2015-2024
Hôpital Militaire Moulay Ismail
2013-2024
Hospital Fatuma Bourguiba Monastir
2021
Military Hospital
2021
Centre Hospitalier Universitaire Ibn Rochd
1999
Homozygosity for the P1104A missense variant of TYK2 Janus kinase is common monogenic etiology primary tuberculosis.
Abstract Background Tuberculosis represents a serious public health problem and significant diagnostic therapeutic challenge worldwide. Molecular techniques are crucial in the World Health Organization’s new tuberculosis control strategy. This study aims to evaluate performance of GeneXpert MTB/RIF (Cepheid Sunnyvale, CA, United States) diagnosis extra-pulmonary then compare it’s detecting Rifampicin resistance GenoType MTBDRplus (HAIN Life Sciences, Nehren, Germany). Methods Samples from...
Background. Only a minority of individuals infected with Mycobacterium tuberculosis develop clinical tuberculosis. Genetic epidemiological evidence suggests that pulmonary has strong human genetic component. Previous findings in Mendelian predisposition to more severe mycobacterial infections, including by M. tuberculosis, underlined the importance interleukin 12 (IL-12)/interferon γ (IFN-γ) circuit antimycobacterial immunity.
Increased prevalence of latent tuberculosis infection (LTBI) has been observed among high-risk populations such as healthcare workers (HCWs). The results may depend on the method LTBI assessment, interferon-gamma release assay (IGRA) and/or tuberculin skin test (TST). Here, we investigated and risk factors for assessed by both IGRAs TST in HCWs living Morocco, a country with intermediate (TB) endemicity high BCG vaccination coverage. were recruited two Moroccan hospitals, Rabat Meknes. All...
Objectives This study aims to analyze the prevalence and spectrum of epidermal growth factor receptor (EGFR) mutations within Middle East North Africa region, compare findings other parts world, explore geographic disparities EGFR across region. Methods We conducted a literature search using terms “[EGFR] AND [mutation] [Non-Small Cell Lung Cancer] [Middle OR Africa]”, PubMed, Science Direct, Web science, Embase, Scopus, Google scholar. Results A total 15 eligible studies were included 6122...
Tuberculous pyopneumothorax is a rare but serious complication of evolutive pulmonary tuberculosis. We report series 18 cases with tuberculous admitted to the Pneumo-Phthisiology Department Mohammed V Military Teaching Hospital in Rabat between January 2005 and December 2009. Our study included 15 men 3 women, average age was 35 ± 7 years. 4 patients were diabetic. Smoking found 9 cases. Right-sided pneumothorax 13 Chest radiograph showed cavitary lesions extensive bilateral 8 The search for...
L'atteinte pulmonaire au cours de la vascularite urticarienne hypocomplémentémique (VUH) ou syndrome Mc duffie est très rare et pronostique péjoratif. Nous rapportons le cas d'une patiente âgée 55 ans suivie pour VUH depuis 20 ans. Le diagnostic était retenu sur les lésions urticariennes, l'inflammation occulaire, test positif C1q-p par immunodiffusion, avec un faible du taux C1q. La a été traitée des cycles à base cyclophosphamide, corticoïdes cures rituximab alors qu'elle développé une...
Background: Chlamydia pneumoniae (C. pneumoniae) is a respiratory pathogen associated with chronic inflammatory and its detection in human lung cancer suggests involvement cancerogenesis. Our study aimed to evaluate the association between C. infection Lung Cancer disease Moroccans patients control cohorts, through molecular investigation. Methods: The comprised 42 43 healthy controls. All participants provided demographics, Clinical, Toxic behaviors datas, peripheral blood sample for...
We present an extremely rare case of a old man 52 answith hydatid pulmonary embolism caused by direct invasion the artery cyst. Even if it is benign parasitic disease, can lead to serious complications such as arterial, systemic, or multivisceral dissemination being responsible for anaphylactic shock. Because clinical polymorphism, diagnosis be delayed. Therefore, A chest CT angiography gold standard positive diagnosis.
Multiple myeloma is a hematologic malignancy characterized by the proliferation of abnormal plasma cells in bone marrow. common manifestations include pain, osteolytic lesions, and fractures ; systemic symptoms such as anemia, hypercalcemia, renal impairment are also prevalent. Extramedullary multiple (EMM) an uncommon complication that presents only 7% patients with myeloma. We report this study case pneumonia pleural infiltration occurred during progression unrecognized
Prenatal risk factors were the commonest (59%), most important factor was prematurity (21%) followed by asphyxia (19%) and kernicterus (17%), while it unknown in majority of cases (31%). Spastic diplegia accounted for (40%) total cases, spastic quadriplegia (34%), hemiplegia (14%), extrapyramidal (12%). CP major form both sexes, mainly diaplegic (23% males), (17% females). low middle SES (22%, 8% respectively), high equal between (10% both). types rural urban areas being (39%, 16%...
La tuberculose naso-sinusienne primaire est une affection relativement rare voir exceptionnelle. présentation clinique polymorphe et non spécifique. Le diagnostic définitif repose sur l´examen anatomopathologique mycobactériologique d´une pièce biopsique de la lésion. Son pronostic favorable sous antibiothérapie antituberculeuse classique précoce. Cependant, notre observation rapporte rechute cette localisation chez patiente immunocompétente malgré un traitement antituberculeux bien adaptée...
La pemphigoide bulleuse (PB) est la plus frequente des dermatoses bulleuses auto-immunes, touchants preferentiellement le sujet âge de 70 ans. L'origine paraneoplasique PB rarement rapportee. Cette lesion peut apparaitre maniere synchrone ou parfois etre une manifestation revelatrice tumeur. Nous rapportons l'observation d'un jeune patient presentant un cancer bronchique metastatique revele par PB. Chez fumeur, toute justifie recherche d'une neoplasie.