A5101723373- Cancer-related molecular mechanisms research
- Cell Adhesion Molecules Research
- Circular RNAs in diseases
- Tribology and Wear Analysis
- Lubricants and Their Additives
- Geophysics and Sensor Technology
- Polymer Surface Interaction Studies
- Ultrasonics and Acoustic Wave Propagation
- Industrial Technology and Control Systems
- Neuroblastoma Research and Treatments
- Protease and Inhibitor Mechanisms
- Adipose Tissue and Metabolism
- Protein Tyrosine Phosphatases
- RNA Research and Splicing
- MicroRNA in disease regulation
- Atherosclerosis and Cardiovascular Diseases
- Advanced Sensor and Control Systems
- Advanced Computational Techniques and Applications
- Regulation of Appetite and Obesity
- Periodontal Regeneration and Treatments
- Kruppel-like factors research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer
- Angiogenesis and VEGF in Cancer
- melanin and skin pigmentation
Union Hospital
2018-2024
Jilin University
2015-2024
Tongji University
2007-2023
Union Hospital
2017-2021
Lanzhou University
2006-2020
Shanghai Jiao Tong University
2013
Shandong Provincial Hospital
2009
Jilin Medical University
2009
Shanghai Tongji Urban Planning and Design Institute
2005
MicroRNAs (miRNAs) have emerged as critical epigenetic regulators involved in cancer progression. miR-320a has been identified to be a novel tumour suppressive miRNA colorectal (CRC). However, the detailed molecular mechanisms are not fully understood. Here, we reported that inversely associated with CRC aggressiveness both cell lines and clinical specimens. Functional studies demonstrated significantly decreased capability of migration/invasion induced G0/G1 growth arrest vitro vivo....
Long noncoding RNAs (lncRNAs) have been identified as oncogenes or tumor suppressors that are involved in tumorigenesis and chemoresistance. LncRNA XIST expression is upregulated several cancers, however, its biologic role the development of chemotherapy human lung adenocarcinoma (LAD) has not elucidated. This study aimed to observe LAD evaluate clinical significance resistance cells cisplatin. was markedly increased cisplatin-resistant A549/DDP compared with parental A549 shown by qRT-PCR....
While numerous hydrogel dressings are available for treating chronically infected wounds, their clinical application is impeded by intricate preparation processes, low mechanical strength, and frequent reliance on exogenous antimicrobial agents. The latter often leads to antibiotic misuse compromises the bioactivity of cell growth-promoting substances. Therefore, field therapeutic treatment faced with a pressing need prepare high-mechanical-strength hydrogels through facile procedure,...
Realgar, a traditional Chinese medicine, has shown antitumor efficacy in several tumor types. We previously showed that realgar nanoparticles (nano-realgar) had significant antileukemia, anti-lung cancer and anti-liver effects. In addition, the anti-tumor effects of nanorealgar were significantly better than those ordinary realgar.To explore inhibitory molecular mechanisms nano-realgar on migration, invasion metastasis mouse breast cells.Wound-healing migration assays Transwell carried out...
Cutaneous malignant melanoma (CMM) is responsible for ≥1/2 of skin cancer‑related mortalities. The aberrant expression long non‑coding RNAs (lncRNAs) has been associated with the development CMM. However, to best our knowledge, role lncRNA TINCR ubiquitin domain containing (TINCR) in CMM not previously investigated, and thus, current study aimed evaluate this vitro vivo. Reverse transcription‑quantitative PCR (RT‑qPCR) was used analyze microRNA (miR)‑424‑5p expression, RT‑qPCR western...
The formation of long cylindrical wormlike micelles at low temperatures (near 0 °C) is relatively rare. In this work, the effect different salts on viscoelasticity formed by ionic liquid surfactant (1-octadecyl-3-nonyl imidazolium bromide, [C18imC9]Br) and glycerol/1,2-propanediol mixture temperature was studied. rheological measurements revealed that only sodium salicylate (NaSal) can increase [C18imC9]Br up to 15 times existence range. When concentration fixed, [C18imC9]Br/NaSal increases...
Skin damage due to overexposure ultraviolet B (UV-B) radiation can lead the development of cancers and reduce skin's functionality as a vital protective barrier. Epidermal stem cells (ESCs) are pluripotent responsible for skin regeneration healing. Upon exposure UV-B radiation, ESCs produce excess amounts reactive oxygen species (ROS) inflammatory cytokines. However, functional protection is not fully explored. G-protein coupled G protein-coupled receptor 40 (Gpr40) free fatty acid that...
Two methods of inertia simulation, energy compensation method and torque control method, using work electromotor during brake application are discussed in comparison this paper. Mathematical models described. Experiment under various conditions unfolds the rule some key factors including working period electromotor, start point ending condition compensation. Comparison experiment shows advantages over its counterpart. Limitations as well corresponding solutions end.
The piezoelectric bone conduction auditory device (PBCAD) with a rectangular bimorph as driving components was designed based on the principle of conduction(BC), audio signal converted to vibration stimulate nerve via skull create hearing. Finite element analysis vibrator means support and optimize structure program improve equipment sound effects in regional signals low-frequency, experiment PBCAD chalks up curve parameters. Experimental studies show: BC unit can achieve better function (BCAD).