A5057461097- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Decision-Making and Behavioral Economics
- Advanced Memory and Neural Computing
- Neuroscience and Music Perception
- Aesthetic Perception and Analysis
- Olfactory and Sensory Function Studies
- Face Recognition and Perception
- Neuroscience and Neural Engineering
- Neural Networks and Applications
- Color perception and design
McGovern Institute for Brain Research
2023-2025
Massachusetts Institute of Technology
2023-2025
Columbia University
2020-2024
Brain (Germany)
2023-2024
New York University
2017-2024
Howard Hughes Medical Institute
2024
Institute of Cognitive and Brain Sciences
2023
Abstract High-density, integrated silicon electrodes have begun to transform systems neuroscience, by enabling large-scale neural population recordings with single cell resolution. Existing technologies, however, provided limited functionality in nonhuman primate species such as macaques, which offer close models of human cognition and behavior. Here, we report the design, fabrication, performance Neuropixels 1.0-NHP, a high channel count linear electrode array designed enable simultaneous...
The brain makes decisions by accumulating evidence until there is enough to stop and choose. Neural mechanisms of accumulation are established in association cortex, but the site mechanism termination unknown. Here, we show that superior colliculus (SC) plays a causal role terminating decisions, provide for which this occurs. We recorded simultaneously from neurons lateral intraparietal area (LIP) SC while monkeys made perceptual decisions. Despite similar trial-averaged activity, found...
Many tasks used to study decision-making encourage subjects integrate evidence over time. Such are useful understand how the brain operates on multiple samples of information prolonged timescales, but only if actually form their decisions. We explored behavioral observations that corroborate evidence-integration in a number task-designs. Several commonly accepted signs integration were also predicted by non-integration strategies. Furthermore, an model could fit data generated models....
Responses of individual task-relevant sensory neurons can predict monkeys' trial-by-trial choices in perceptual decision-making tasks. Choice-correlated activity has been interpreted as evidence that the responses these are causally linked to judgments. To further test this hypothesis, we studied orientation-selective V1 and V2 while two macaque monkeys performed a fine orientation discrimination task. Although both animals exhibited high level neuronal behavioral sensitivity, only one...
The visual world is richly adorned with texture, which can serve to delineate important elements of natural scenes. In anesthetized macaque monkeys, selectivity for the statistical features texture weak in V1, but substantial V2, suggesting that neuronal activity V2 might directly support perception. To test this, we investigated relation between single cell V1 and simultaneously measured behavioral judgments texture. We generated stimuli along a continuum naturalistic phase-randomized noise...
The visual world is richly adorned with texture, which can serve to delineate important elements of natural scenes. In anesthetized macaque monkeys, selectivity for the statistical features texture weak in V1, but substantial V2, suggesting that neuronal activity V2 might directly support perception. To test this, we investigated relation between single cell V1 and simultaneously measured behavioral judgments texture. We generated stimuli along a continuum naturalistic phase-randomized noise...
Neurobiological investigations of perceptual decision-making have furnished the first glimpse a flexible cognitive process at level single neurons. Neurons in parietal and prefrontal cortex are thought to represent accumulation noisy evidence, acquired over time, leading decision. Neural recordings averaged many decisions provided support for deterministic rise activity termination bound. Critically, it is unobserved stochastic component that confer variability both choice decision time....
Neurobiological investigations of perceptual decision-making have furnished the first glimpse a flexible cognitive process at level single neurons ( Shadlen and Newsome, 1996 ; Kiani, 2013 ). Neurons in parietal prefrontal cortex Kim Shadlen, 1999 Romo et al., 2004 Hernández 2002; Ding Gold, 2012 ) are thought to represent accumulation noisy evidence, acquired over time, leading decision. Neural recordings averaged many decisions provided support for deterministic rise activity termination...
Neurobiological investigations of perceptual decision-making have furnished the first glimpse a flexible cognitive process at level single neurons. Neurons in parietal and prefrontal cortex are thought to represent accumulation noisy evidence, acquired over time, leading decision. Neural recordings averaged many decisions provided support for deterministic rise activity termination bound. Critically, it is unobserved stochastic component that confer variability both choice decision time....
The brain makes decisions by accumulating evidence until there is enough to stop and choose. Neural mechanisms of accumulation are well established in association cortex, but the site mechanism termination unknown. Here, we elucidate a for neurons primate superior colliculus. We recorded simultaneously from lateral intraparietal cortex (LIP) colliculus (SC) while monkeys made perceptual decisions, reported eye-movements. Single-trial analyses revealed distinct dynamics: LIP tracked on each...
Neurobiological investigations of perceptual decision-making have furnished the first glimpse a flexible cognitive process at level single neurons (Shadlen and Newsome, 1996; Shadlen Kiani, 2013). Neurons in parietal prefrontal cortex (Kim Shadlen, 1999; Romo et al., 2004; Hernández 2002; Ding Gold, 2012) are thought to represent accumulation noisy evidence, acquired over time, leading decision. Neural recordings averaged many decisions provided support for deterministic rise activity...
Neurobiological investigations of perceptual decision-making have furnished the first glimpse a flexible cognitive process at level single neurons ( Shadlen and Newsome, 1996 ; Kiani, 2013 ). Neurons in parietal prefrontal cortex Kim Shadlen, 1999 Romo et al., 2004 Hernández 2002 Ding Gold, 2012 ) are thought to represent accumulation noisy evidence, acquired over time, leading decision. Neural recordings averaged many decisions provided support for deterministic rise activity termination...
ABSTRACT Many tasks used to study decision-making encourage subjects integrate evidence over time. Such are useful understand how the brain operates on multiple samples of information prolonged timescales, but only if actually form their decisions. We explored behavioral observations that corroborate evidence-integration in a number task-designs. Several commonly accepted signs integration were also predicted by non-integration strategies. Furthermore, an model could fit data generated...