A5075183855- Phagocytosis and Immune Regulation
- Lysosomal Storage Disorders Research
- HIV Research and Treatment
- Genomics and Chromatin Dynamics
- Epigenetics and DNA Methylation
- Immunotherapy and Immune Responses
- Aquaculture Nutrition and Growth
- Immune cells in cancer
- Biochemical Analysis and Sensing Techniques
- Aquaculture disease management and microbiota
- Ergonomics and Musculoskeletal Disorders
- Single-cell and spatial transcriptomics
- RNA modifications and cancer
University of Chinese Academy of Sciences
2024
Institute of Hydrobiology
2024
Chinese Academy of Sciences
2024
Shanghai Jiao Tong University
2009-2021
Bridge University
2021
State Key Laboratory of Oncogene and Related Genes
2020-2021
Abstract Immortalized cell lines have long been used as model systems to systematically investigate biological processes under controlled and reproducible conditions, providing insights that greatly advanced cellular biology medical sciences. Recently, the widely monocytic leukemia line, THP-1, was comprehensively examined understand mechanistic relationships between 3D chromatin structure transcription during trans-differentiation of monocytes macrophages. To corroborate these observations...
Fish show variation in feeding habits to adapt complex environments. However, the genetic basis of preference and corresponding metabolic strategies that differentiate remain elusive. Here, by comparing whole genome a typical carnivorous fish (
Monocyte-to-macrophage trans-differentiation has long been studied to better understand this immunological response and aspects of developmental processes more generally. A key question is the nature corresponding changes in chromatin conformation its relationship transcriptome during process. This especially intriguing since not associated with progression through mitosis, often considered a necessary step for gross chromosomal structure. Here, we characterized transcriptional genomic...
Abstract Immortalized cell lines have long been used as model systems to systematically investigate biological processes under controlled and reproducible conditions, providing insights that greatly advanced cellular biology medical sciences. Recently, the widely monocytic leukemia line, THP-1, was comprehensively examined understand mechanistic relationships between 3D chromatin structure transcription during trans-differentiation of monocytes macrophages. To corroborate these observations...