A5052254486- Nuclear physics research studies
- Regulation of Appetite and Obesity
- Quantum Chromodynamics and Particle Interactions
- Nuclear Physics and Applications
- Particle physics theoretical and experimental studies
- Biochemical Analysis and Sensing Techniques
- Atomic and Subatomic Physics Research
- Quantum, superfluid, helium dynamics
- Advanced NMR Techniques and Applications
- High-Energy Particle Collisions Research
- Diabetes Treatment and Management
- Diet and metabolism studies
- Steroid Chemistry and Biochemistry
- Adipose Tissue and Metabolism
- Superconducting Materials and Applications
- Cholesterol and Lipid Metabolism
- Pancreatic function and diabetes
- Radiation Detection and Scintillator Technologies
- Helicobacter pylori-related gastroenterology studies
- Advanced Chemical Physics Studies
- Chemical Synthesis and Analysis
- X-ray Spectroscopy and Fluorescence Analysis
- Neuropeptides and Animal Physiology
- Particle accelerators and beam dynamics
- Pharmacology and Obesity Treatment
University of Miyazaki
2014-2024
Yamagata University
2002-2019
Muroran Institute of Technology
2013-2016
Mitsubishi Chemical (Japan)
2004-2015
Mitsubishi Tanabe Pharma Corporation
2009-2015
RIKEN Nishina Center
2007-2012
Yamagata University Hospital
1974-2010
Miyazaki Welfare Medical College
1995-2009
Tohoku University
1965-2008
Tokyo Institute of Technology
1981-2007
Ghrelin is primarily secreted from the stomach and has been implicated in coordination of eating behavior weight regulation. The effects Helicobacter pylori infection on plasma ghrelin concentration gastric production still have not well known. We determined a total 160 consecutive individuals with normal body mass index including 110 H. pylori-infected 50 pylori-negative subjects. expression levels mRNA ghrelin-producing cells mucosa were quantified real-time quantitative RT-PCR...
Summary Objective In recent years great advances have been made in our understanding of the peripheral signals produced within gastrointestinal tract that regulate appetite, such as ghrelin and peptide YY (PYY). While elicites hunger signals, PYY satiety. Therefore, alterations hormone physiology may play a role pathogenesis bulimia nervosa (BN). this study, we investigated postprandial profile levels patients with BN. Design Postprandial plasma insulin glucose responses were measured 10 BN...
There are contradictory reports on the relationship between Helicobacter pylori and circulating ghrelin. We sought to clarify influence of H. infection gastric plasma ghrelin dynamics in humans.Using endoscopic biopsies from corpus 56 pylori-infected patients 25 uninfected subjects, mRNA expression levels peptide contents were measured by real-time polymerase chain reaction radioimmunoassay, respectively. also concentrations analyzed numbers immunoreactive cells fundic gland area. Fifty-one...
Abstract Heavy meromyosin (HMM) of myosin II and cofilin each binds to actin filaments cooperatively forms clusters along the filaments, but it is unknown whether two cooperative bindings are correlated what physiological roles they have. Fluorescence microscopy demonstrated that HMM-GFP cofilin-mCherry bound different parts when were added simultaneously in 0.2 μM ATP, indicating mutually exclusive. In 0.1 mM motor domain (S1) strongly inhibited formation filaments. Under this condition,...
Endothelial dysfunction is a risk factor for cardiovascular disease in patients with diabetes. We hypothesized that imeglimin, novel oral hypoglycemic agent, would improve endothelial function.In this study, imeglimin was administered to type 2 diabetes and HbA1c ≥ 6.5% who were not receiving insulin therapy. A meal tolerance test (592 kcal, glucose 75.0 g, fat 28.5 g) performed before 3 months after administration, function, blood glucose, insulin, glucagon, triglycerides evaluated....
\ensuremath{\eta} mesons emitted from the photoproduction off protons were measured for $0.70\ensuremath{\leqslant}{E}_{\ensuremath{\gamma}}\ensuremath{\leqslant}1.15$ GeV. The $\ensuremath{\gamma}p\ensuremath{\rightarrow}\ensuremath{\eta}p$ reaction process was separated $\ensuremath{\pi}\ensuremath{\eta}p$ final state by momentum difference of ${E}_{\ensuremath{\gamma}}\ensuremath{\geqslant}930$ MeV. angular distributions obtained and excitation function are essentially in good agreement...
We present data on the inclusive scattering of polarized electrons from a 3He target at energies 0.862 to 5.06 GeV, obtained angle 15.5°. Our include measurements quasielastic peak, through nucleon resonance region, and beyond, were used determine virtual photon cross-section difference σ1/2−σ3/2. extract extended Gerasimov-Drell-Hearn integral for neutron in range four-momentum transfer squared Q2 0.1–0.9 GeV2.Received 15 May 2002DOI:https://doi.org/10.1103/PhysRevLett.89.242301©2002...
We have measured the spin structure functions $g_1$ and $g_2$ of $^3$He in a double-spin experiment by inclusively scattering polarized electrons at energies ranging from 0.862 to 5.07 GeV off target 15.5$^{\circ}$ angle. Excitation covered resonance onset deep inelastic regions. determined for first time $Q^2$ evolution $\Gamma_1(Q^2)=\int_0^{1} g_1(x,Q^2) dx$, $\Gamma_2(Q^2)=\int_0^1 g_2(x,Q^2) dx$ $d_2 (Q^2) = \int_0^1 x^2[ 2g_1(x,Q^2) + 3g_2(x,Q^2)] neutron range 0.1 GeV$^2$ $\leq Q^2...
Journal Article Further studies of the binding specificity leukocyte adhesion molecule, L-selectin, towards sulphated oligosaccharides—suggestion a link between selectin- and integrin-mediated lymphocyte systems Get access Paula J. Green, Green 1The Glycobiology Group, The Glycosciences Laboratory, Northwick Park HospitalWatford Road, Harrow, Middlesex HA1 3UJ, UK6Present address: Department Expeimental Pathology, UMDS Guy's St Thomas's Hospitals, University LondonLondon Bridge, London SE1...
An experiment measuring electroproduction of hypernuclei has been performed in hall A at Jefferson Lab on a 12C target. In order to increase counting rates and provide unambiguous kaon identification two superconducting septum magnets ring imaging Cherenkov detector were added the standard equipment. unprecedented energy resolution less than 700 keV FWHM achieved. Thus, observed (Lambda)(12)B spectrum shows for first time identifiable strength core-excited region between ground-state s-wave...
Differential and total cross sections of the D(γ,η)pn reaction have been measured for photon energies between 600 1150 MeV. The data provide information γn →ηn above Eγ ≥ 800 section shows a narrow resonance structure peaked at = 1020 angular distribution coefficients together with are compared calculation isobar model by using impulse approximation. Although spin parity cannot be determined unambiguously, negative assignment gives better fit to data.
Ghrelin, an acylated peptide produced predominantly in the stomach, stimulates feeding and growth hormone (GH) secretion via interaction with GH secretagogue receptor. Ghrelin molecules are present two major endogenous forms, form (ghrelin) a des-acylated (des-acyl ghrelin). Recent studies indicated that aerobic exercise did not change plasma total ghrelin levels, however, dynamics of circulating des-acyl during remains unclear. The purpose this study is to examine effects moderate intensity...
Orlistat, an anti-obesity agent, inhibits the metabolism and absorption of dietary fat by inactivating pancreatic lipase in gut. The effect orlistat on gut microbiota Japanese individuals with obesity is unknown. This study aimed to explore effects fatty acid obesity. Fourteen subjects visceral (waist circumference ≥85 cm) took orally at a dose 60 mg, 3 times day for 8 weeks. Body weight; waist circumference; area; levels short-chain acids, microbiota, metabolites feces, gastrointestinal...