A5030184436- Antifungal resistance and susceptibility
- Fungal and yeast genetics research
- Retinoids in leukemia and cellular processes
- Retinal Diseases and Treatments
- Plant Pathogens and Fungal Diseases
- Plant-Microbe Interactions and Immunity
- Atherosclerosis and Cardiovascular Diseases
- Ovarian function and disorders
- Reproductive Physiology in Livestock
- Bat Biology and Ecology Studies
- Seed and Plant Biochemistry
- Structural Engineering and Vibration Analysis
- Reproductive System and Pregnancy
- Genetic Mapping and Diversity in Plants and Animals
- Animal Behavior and Reproduction
- Genetics and Plant Breeding
- Wildlife Ecology and Conservation
University of Southern California
2022-2025
Doheny Eye Institute
2019
University of California, Los Angeles
2019
Abstract Sexual size dimorphism (SSD) is common throughout the animal kingdom, but its evolution and development remain difficult to explain given most of genome shared between males females. Sex-biased regulation genes via sex hormone signaling offers an intuitive mechanism by which females could develop different body sizes. One prediction this hypothesis that magnitude SSD scales with number androgen response elements or estrogen elements, DNA motifs receptors bind. Here we test using 268...
Abstract While spoken language is unique to humans, many features of human communication are shared with great apes, including the use signals in multiple modalities such as vocalizations, gestures, and facial expressions. Communication can be unimodal (involving a single modality) or multimodal (combining simultaneously). Here, we examined age-related differences bonobo ( Pan paniscus) signals. We assessed all expressions, combinations produced by captive bonobos across variety behavioral...
Age-related macular degeneration (AMD) is a leading cause of blindness in the developed world. The retinal pigment epithelium (RPE) critical site pathology AMD. Oxidative stress plays key role development We generated chimeric high-density lipoprotein (HDL), mimetic peptide named HM-10/10, with anti-oxidant properties and investigated its potential for treatment disease using cell culture animal models RPE photoreceptor (PR) degeneration. Treatment HM-10/10 prevented human fetal death caused...
Abstract In mammals, a temporary endocrine gland called the corpus luteum forms on ovary shortly after ovulation and is required for initiation maintenance of early pregnancy. However, persists even when fertilization or pregnancy does not occur, species-specific variation in length this persistence remains enigmatic. Here we perform comparative evolutionary study across 72 species show that lifespan nonpregnant females positively correlated with gestation length. We argue most likely...
Abstract Determining how genetic polymorphisms enable certain fungi to persist in mammalian hosts can improve understanding of opportunistic fungal pathogenesis, a source substantial human morbidity and mortality. We examined the basis persistence mice using cross between clinical isolate lab reference strain budding yeast Saccharomyces cerevisiae. Employing chromosomally encoded DNA barcodes, we tracked relative abundances 822 genotyped, haploid segregants multiple organs over time...
The constant increase in temperatures, as a consequence of climate change, affects the regions where wheat is grown and thus demands an adjustment crop cycle to shorter periods with purpose decreasing high temperature stress. Therefore, discovery new genetic sources flowering modulation development molecular tools that enable their use, take main role breeding. In this study, effect Ppd-1 on time was evaluated bread biparental population, under controlled conditions. Novel markers for Ppd-A1...
Abstract Determining how genetic polymorphisms enable certain fungi to persist in mammalian hosts can improve understanding of opportunistic fungal pathogenesis, a source substantial human morbidity and mortality. We examined the basis persistence mice using cross between clinical isolate lab reference strain budding yeast Saccharomyces cerevisiae . Employing chromosomally-encoded barcodes, we tracked relative abundances 822 genotyped, haploid segregants multiple organs over time performed...