A5025833926- Ion channel regulation and function
- Cardiac electrophysiology and arrhythmias
- DNA and Nucleic Acid Chemistry
- Advanced biosensing and bioanalysis techniques
- Advanced Proteomics Techniques and Applications
- Chemical Synthesis and Analysis
- Fungal and yeast genetics research
- Mass Spectrometry Techniques and Applications
- Protein Structure and Dynamics
- CRISPR and Genetic Engineering
- Lipid Membrane Structure and Behavior
- Pesticide and Herbicide Environmental Studies
- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Renal and related cancers
- Effects and risks of endocrine disrupting chemicals
- Biofuel production and bioconversion
- Genetics, Bioinformatics, and Biomedical Research
- Membrane-based Ion Separation Techniques
- Metal complexes synthesis and properties
- Reflective Practices in Education
- Reproductive Health and Technologies
- Machine Learning in Bioinformatics
- bioluminescence and chemiluminescence research
- Gut microbiota and health
Michigan State University
2008-2025
Iowa State University
2020-2023
Islamic Azad University of Varamin
2020
Islamic Azad University Tonekabon
2018
University of Toronto
2015-2017
McMaster University
2015
Sharif University of Technology
2007
The protein corona formed on nanoparticles (NPs) has potential as a valuable diagnostic tool for improving plasma proteome coverage. Here, we show that spiking small molecules, including metabolites, lipids, vitamins, and nutrients into can induce diverse patterns otherwise identical NPs, significantly enhancing the depth of profiling. coronas polystyrene NPs when exposed to treated with an array molecules allows detection 1793 proteins marking 8.25-fold increase in number quantified...
The protein corona, a dynamic biomolecular layer that forms on nanoparticle (NP) surfaces upon exposure to biological fluids is emerging as valuable diagnostic tool for improving plasma proteome coverage analyzed by liquid chromatography-mass spectrometry (LC-MS/MS). Here, we show spiking small molecules, including metabolites, lipids, vitamins, and nutrients (namely, glucose, triglyceride, diglycerol, phosphatidylcholine, phosphatidylethanolamine, L-α-phosphatidylinositol, inosine...
This study investigates the preparation and characterization of PVC blended with PMMA‐PEG copolymer to enhance antifouling properties membranes for oily wastewater treatment. Membranes were fabricated via non‐solvent‐induced phase separation (NIPS) method. The membrane was characterized by FTIR, DSC, FESEM, AFM, contact angle, water content, porosity, pure flux (PWF), mechanical strength analyses. results DSC analysis showed that all had single glass transition temperature indicating...
Perfluorooctanoic acid (PFOA) is an environmentally persistent perfluoroalkyl substance that widely used in consumer products. Exposure to PFOA associated with reproductive and developmental effects including endocrine disruption, delayed puberty girls, decreased fetal growth. In the United States, obesity affects 40% of women 20% higher rates minority females. Obesity causes infertility, poor oocyte quality, miscarriage, offspring defects. This study proposed exposure would impact estrous...
Modulating gene expression in macrophages can be used to improve tissue regeneration and redirect tumor microenvironments (TME) toward positive therapeutic outcomes. We have developed Bacillus subtilis as an engineered endosymbiont (EES) capable of residing inside the eukaryotic host cell cytoplasm controlling fate macrophages. Secretion mammalian transcription factors (TFs) from B. that expresses listeriolysin O (LLO; allowing EES escape destruction by macrophage) modulated surface markers,...
Abstract Glyphosate (GLY) is an herbicide used for rural and urban weed control. Urinary GLY in women associated with shortened gestational length yet effects of on offspring due to maternal exposure are unclear. This study tested the hypothesis that chronic pre-conceptional would cause phenotypic molecular changes F1 offspring. Female C57BL/6 mice (7-week-old; n = 40) received saline vehicle control (CT; 20) or (2 mg/kg; daily per os 10 weeks. At dosing completion, females were housed...
The heterogeneous dielectric generalized Born (HDGB) implicit membrane formalism is extended by the addition of a van der Waals dispersion term to better describe nonpolar components free energy solvation. new model, termed HDGBvdW, improves estimates in hydrophobic interior membrane, where polar and charged species are rarely found interactions become significant. for environment extends model from Gallicchio et al. (J. Comput. Chem. 2004, 25, 479) combining separate contributions each...
Redesigning protein surface topology to improve target binding holds great promise in the search for highly selective therapeutics. While significant improvements can be achieved using natural amino acids, introduction of non-canonical residues vastly increases sequence space and thus chance significantly out-compete native partners. The potency inhibitors further enhanced by synthesising mirror image, D-amino versions. This renders them non-immunogenic makes resistant proteolytic...
Exposure to glyphosate (GLY), a commonly used herbicide, is supported by urinary detection and associated with shortened gestation in women. This study tested the hypothesis that chronic low-dose pre-conceptional GLY exposure would affect maternal ovarian function mid- post-gestation. Mice (C57BL/6; n = 40) were exposed per os saline vehicle control (CT; 20) or (2 mg/kg; daily for 10 weeks starting at 7 of age. Post-exposure, females impregnated euthanized day 14 (GD14) post-weaning (PW)....
The new dinuclear copper(II) complexes, Cu(II)M(II) (M = Mn, Co, Ni, Cu), of a phenol-based compartmental ligand, having dissimilar N(amine)2O2 and N(imine)2O2 coordination sites have been synthesized. In this system there are two different compartments, one has piperazinyl nitrogens phenolic oxygens the other compartment meso-stilbenediamine as coordinating sites. complexes were characterized by elemental analysis, IR electronic spectra well conductivity measurements. Dinuclear prepared...
The Impact of Using Podcasts on Iranian Autonomous /Non-Autonomous EFL Learners' Listening Comprehension Ability at Pre-Intermediate Level
Deamidation plays an important role in biochemical phenomena such as aging. The of the n + 1 residue on deamidation asparagine (asparagine being nth residue) three pentapeptide chains (GGNGG, GGNMG and GGNIG) has been analysed with hybrid computational tools. Potentials mean force at 300 K were calculated from MD/replica exchange simulations using weighted histogram analysis (WHAM) explicit water. snapshots clustered taking into account requirements plausible mechanisms, tautomerisation side...
The objective was to evaluate the prebiotic effects of a milled whole cranberry beverage on modulating gut microbiota in young adults. Adults (n = 17; ages 18–42 y; BMI 30.5 ± 3.1 kg/m2) were enrolled 60-d, two-period, randomized, placebo-controlled, crossover clinical study. Throughout study, participants fed standardized 10-d cycle menu site. During each 20-d treatment period, consumed twice daily or placebo (240 mL per serving). Treatment periods separated by an 11-wk washout period and...