A5018182164- Cancer Immunotherapy and Biomarkers
- Renal and related cancers
- Vascular Malformations and Hemangiomas
- Polyamine Metabolism and Applications
- Chemokine receptors and signaling
- Lung Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Tumors and Oncological Cases
- Mast cells and histamine
Xinxiang Central Hospital
2024
Xinxiang Medical University
2024
Zhengzhou University
2020-2023
Henan Cancer Hospital
2023
Mammalian target of rapamycin (mTOR) has recently emerged as a promising for the treatment several human cancer types. Rapamycin, classical mTOR inhibitor, been shown to be effective an antitumour therapy in variety preclinical trials. However, clinical use limited by its poor water solubility, low bioavailability, and instability circulation. In this manuscript, we described preparation rapamycin-loaded glucan particle (GP)/chitosan (CS)/tripolyphosphate (TPP)/alginate (ALG) microparticles...
Objective: To investigate the clinicopathological and molecular characteristics of pulmonary enteric adenocarcinoma (PEAC). Methods: The clinical pathological data 19 cases PEAC in Affiliated Cancer Hospital Zhengzhou University were retrospectively collected from 2015 to 2019. Immunohistochemistry (IHC) was used detect relevant immunophenotypes, amplification refractory mutation system (ARMS) fluorescence situ hybridization (FISH) expression EGFR, KRAS ALK genes. patients followed up,...
目的： 探讨婴儿性血管瘤（infantile hemangioma，IH）临床病理学特征。 方法： 搜集2013—2020年河南省人民医院病理科IH确诊病例52例，对其形态学、免疫表型及PIK3CA、GNAQ基因变异情况进行分析。 结果： 52例IH女患儿37例，男患儿15例，发病部位有四肢、躯体和头颈部。病变外观均呈鲜红色或暗红色斑块，形态学上，肿瘤组织呈分叶状生长，增殖期血管内皮细胞密集成片，呈卵圆形或上皮样形态，血管腔不明显，可见细胞凋亡；消退期血管内皮细胞较稀疏，呈纤细梭形或扁平状，血管腔可见，多量脂肪纤维组织增生。免疫组织化学结果显示血管内皮细胞表达葡萄糖转运蛋白1、CD15及其他内皮相关标志物；PIK3CA、GNAQ基因均未见突变。 结论： IH是发生于婴幼儿较常见的血管源性良性肿瘤，形态学以分叶状结构生长，伴血管内皮细胞增生及微血管腔形成为主，增殖期需与卡波西型血管内皮瘤、先天性血管瘤等鉴别，消退期需与脉管畸形等鉴别。.
e15506 Background: Colorectal cancer (CRC) is one of the most common types malignant tumors, and its incidence increasing year by year.Chemokines are small cytokines or signaling proteins secreted cells. They have ability to induce directional chemotactic migration nearby responding cells can mediate intracellular signal transduction binding 18 G protein-coupled receptor families.C-X-C motif chemokine 3 (CXCR3) activated three Interferon-γ inducible ligands CXCL9, CXCL10 CXCL11 encodes 368...