A5084330345- Long-Term Effects of COVID-19
- Alzheimer's disease research and treatments
- Parkinson's Disease Mechanisms and Treatments
- Schizophrenia research and treatment
- Advanced Glycation End Products research
- Stuttering Research and Treatment
- Intensive Care Unit Cognitive Disorders
- Bipolar Disorder and Treatment
- Machine Learning in Healthcare
- Sleep and related disorders
- Psychiatric care and mental health services
- Geriatric Care and Nursing Homes
- Cholinesterase and Neurodegenerative Diseases
- Restless Legs Syndrome Research
- Sleep and Wakefulness Research
- COVID-19 and Mental Health
- Dementia and Cognitive Impairment Research
Weatherford College
2024
Juntendo University
2016-2024
COVID-19 has a range of complications, from no symptoms to severe pneumonia. It can also affect multiple organs including the nervous system. affects brain, leading neurological such as delirium. Delirium, sudden change in consciousness, increase risk death and prolong hospital stay. However, research on delirium prediction patients with is insufficient. This study aimed identify new factors that could predict onset using machine learning (ML) applied nursing records. retrospective cohort...
Patients with bipolar disorder often report self-perceived treatment resistance. However, it is not known to what extent due actual The Juntendo University provides “Bipolar Disorder Treatment Rebuilding Program,” in which patients self-reported resistant are hospitalized for 2 weeks and undergo detailed examinations. In this study, we our experience the initial 43 during one half years after launch of program. Among who underwent full assessment, only was regarded as having genuine...
<b><i>Background/Aims:</i></b> Mutations in the presenilin 2 <i>(PSEN2)</i> gene cause familial Alzheimer's disease (AD). Common polymorphisms affect activity and increase risk of AD. Nonsynonymous <i>PSEN2</i> showed Lewy body dementia (LBD) phenotypes clinically. Therefore, we aimed to investigate whether were associated with AD or LBD. <b><i>Methods:</i></b> Seven single nucleotide (SNPs) analyzed using a case-control...
Background/Aims Interaction of receptor for advanced glycation end products (RAGE) with amyloid‐β increases amplification oxidative stress and plays pathological roles in Alzheimer's disease (AD). Oxidative leads to α‐synuclein aggregation is also a major contributing factor the pathogenesis Lewy body dementias (LBDs). Therefore, we aimed investigate whether RAGE gene polymorphisms were associated AD LBDs. Methods Four single nucleotide (SNPs)—rs1800624, rs1800625, rs184003, rs2070600—of...
To investigate the real-world effectiveness and safety of lemborexan for treating comorbid insomnia associated with other psychiatric disorders, whether lemborexant helps reduce dose benzodiazepines (BZs).This retrospective observational study was conducted on outpatients inpatients treated by physicians Juntendo University Hospital Mental Clinic between April 2020 December 2021.Data 649 patients who were eventually enrolled. About 64.5% classified as responder group. Response rates ≥60%...
Objective: We aimed to investigate how primary care physicians (PCPs) in Japan use antipsychotics for treating the behavioural and psychological symptoms of dementia (BPSD).