A5008065857- Essential Oils and Antimicrobial Activity
- Bee Products Chemical Analysis
- Natural product bioactivities and synthesis
- Synthesis and biological activity
- Bacterial biofilms and quorum sensing
- Dental materials and restorations
- Semiconductor materials and devices
- Curcumin's Biomedical Applications
- Cannabis and Cannabinoid Research
- Phytochemicals and Antioxidant Activities
- Analytical Chemistry and Sensors
- Phytochemistry and Biological Activities
- Antimicrobial Peptides and Activities
- Advanced Drug Delivery Systems
- Coconut Research and Applications
- Dental Trauma and Treatments
- Endodontics and Root Canal Treatments
- Synthesis and Characterization of Heterocyclic Compounds
- Mesoporous Materials and Catalysis
- Antifungal resistance and susceptibility
Universidade Federal de Uberlândia
2024-2025
Institute of Biomedical Science
2024
Abstract Candida species have been responsible for a high number of invasive infections worldwide. In this sense, Rottlerin has demonstrated wide range pharmacological activities. Therefore, study aimed to evaluate the antifungal, antibiofilm and antivirulence activity in vitro against spp. its toxicity antifungal vivo. showed all yeasts evaluated, presenting Minimum Inhibitory Fungicidal Concentration (MIC MFC) values 7.81 > 1000 µg/mL. Futhermore, it was able significantly inhibit...
Artepillin C, drupanin, and plicatin B are prenylated phenylpropanoids that naturally occur in Brazilian green propolis. In this study, these compounds eleven of their derivatives were synthesized evaluated for vitro antimicrobial activity against a representative panel oral bacteria terms minimum inhibitory concentration (MIC) bactericidal (MBC) values. Plicatin (
In this study, fifteen N-methyl-4-piperidone-derived monoketone curcuminoids (MKCs) were synthesized using an environmentally friendly base-catalyzed Claisen-Schmidt condensation between aromatic aldehyde (R-PhCHO) and N-methy-4-piperidonein ethanol NaOH as the catalyst. These compounds evaluated for their antibacterial activity against a representative panel of cariogenic bacteria, along with antifungal Candida krusei C. albicans. The antimicrobial was determined based on Minimum Inhibitory...
Background/Objectives: Dental caries and candidiasis are major health problems worldwide. is caused by cariogenic bacteria, especially those belonging to the Streptococcus genus, whereas Candida species. In this study, antimicrobial activity of a series synthetic N-methyl-4-piperidone-derived monoketone curcuminoids (MKCs) against albicans, C. krusei, representative panel bac-teria was assessed. Methods: Fifteen MKCs were synthesized using an environmentally friendly base-catalyzed...
Background/Objectives: Dental caries and candidiasis are major health problems worldwide. is caused by cariogenic bacteria, especially those belonging to the Streptococcus genus, whereas Candida species. In this study, antimicrobial activity of a series synthetic N-methyl-4-piperidone-derived monoketone curcuminoids (MKCs) against albicans, C. krusei, representative panel bacteria was assessed. Methods: Fifteen MKCs were synthesized using an environmentally friendly base-catalyzed...
Artepillin C, drupanin, and plicatin B are prenylated phenylpanoids naturally occurring in Brazilian green propolis. In this study, these compounds eleven derivatives were synthesized evaluated for their vitro antimicrobial activity against a representative panel of cariogenic bacteria terms minimum inhibitory concentration (MIC) values. Plicatin (2) its hydrogenated derivative 8 (2’,3’,7,8-tetrahydro-plicatin B) the most active compounds. displayed strong all tested (MIC = 31.2 μg/mL). On...
The study evaluated the preservative potential of Lafoensia replicata Pohl. leaf extracts in cosmetics, highlighting their antioxidant, antimicrobial, and vitro cytotoxic activities for ethanolic extract prepared by maceration tincture method. Total phenol content showed a higher concentration tinctures, LC-MS/MS-ESI-QTOF analysis, flavonoids, hydrolyzed tannins, phenolic acids were identified. high antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Candida...
Abstract We have studied repositioning of carvedilol (an antihypertensive drug) incorporated into MCM-41 mesoporous silica. The proposes a reduction in the slow pace discovery new drugs, as well toxicological safety and significant high research costs, making it an attractive strategy for researchers large pharmaceutical companies. obtained by template synthesis functionalized post-synthesis grafting with aminopropyltriethoxysilane (APTES) only or folic acid (FA), which gave MCM-41-APTES...
Bacterial resistance and systemic risks associated with periodontitis underscore the need for novel antimicrobial agents. Cannabis sativa is a promising source of molecules, cannabidiol (CBD) attracts significant interest. This study evaluated antibacterial antibiofilm activity CBD against periodontopathogens, assessed its toxicity in vivo model.