A5101367636- Probiotics and Fermented Foods
- Microbial infections and disease research
- Antimicrobial Peptides and Activities
- Enterobacteriaceae and Cronobacter Research
- Milk Quality and Mastitis in Dairy Cows
- Extracellular vesicles in disease
- Bacterial Genetics and Biotechnology
- Pharmaceutical and Antibiotic Environmental Impacts
- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
- MicroRNA in disease regulation
- Immunotherapy and Immune Responses
- Ferroptosis and cancer prognosis
- vaccines and immunoinformatics approaches
- Insect Resistance and Genetics
- Gut microbiota and health
China Agricultural University
2023-2025
Abstract Background Ferroptosis is characterized by increased production of reactive oxygen species (ROS) and membrane lipid peroxidation that can exacerbate inflammatory damage. Extracellular vesicles (EVs) isolated from bovine milk have many biological functions, including antioxidant properties. However, the role EVs on Klebsiella pneumoniae -induced ferroptosis oxidative stress in mammary epithelial cells (bMECs) murine tissue unclear. In this study, were colostrum, mature clinical...
Klebsiella pneumoniae can cause severe clinical mastitis in dairy cows, with K. type K57 (K57-KP) being the most common capsular serotype. To identify virulence factors and antimicrobial-resistance (AMR) genes of K57-KP varying virulence, Galleria mellonella (greater wax moth) larvae were infected as a screening model to characterize 90 strains, 10 11 strains defined virulent or attenuated, respectively, based on larval survival rates. Next, these 21 isolates was subsequently confirmed...
Non-aureus staphylococci (NAS) are an essential group of bacteria causing antimicrobial resistant intramammary infections in livestock, particularly dairy cows. Therefore, bacteriophages emerge as a potent bactericidal agent for NAS mastitis. This study aimed to obtain NAS-specific using bacterial strains isolated from cows with mastitis, subsequently evaluating their morphological, genomic, and lytic characteristics. Four distinct were recovered sewage or the environment Chinese farms;...
In China's expanding dairy industry, a lack of oversight regarding antimicrobial use and increasing resistance are evident. Selective treatments cows for clinical mastitis or dry cow therapy proposed to promote judicious without adversely impacting cattle health. These approaches have been successfully implemented on farms in other countries.