A5073105422- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Monoclonal and Polyclonal Antibodies Research
- SARS-CoV-2 and COVID-19 Research
- Chronic Lymphocytic Leukemia Research
- Glycosylation and Glycoproteins Research
An approach toward novel neutralizing IgY polyclonal antibodies (N-IgY-pAb) against SARS-CoV-2 S-ECD was developed.The N-IgY-pAb and its intranasal spray response the wild type ("'WH-Human 1") virus, variants of Delta or Omicron were up to 98%. Unique virus peptides binding screened by a proteome microarray.Seventeen mutation-free with Z-score > 3.0 identified as potent targets from total 966 peptides. The new findings show that one is in RBM domain (461LKPFERDISTEIYQA475 ), two are NTD...
Serum thymidine kinase 1 protein (STK1p) concentration has been used successfully as a reliable proliferating serum biomarker in early tumour discovery and clinical settings. It is detected by an enhanced chemiluminescence (ECL) dot blot assay with the biotin-streptavidin (BSA) platform (a gold standard) based on chicken anti-human IgY polyclonal antibody (hTK1-IgY-pAb). However, ECL blotting semiautomatic method that limited to large-scale applications due differences among batches of...