A5100647717- Pharmacological Effects of Natural Compounds
- Metabolomics and Mass Spectrometry Studies
- Healthcare and Venom Research
- Bee Products Chemical Analysis
- Ginseng Biological Effects and Applications
- Gut microbiota and health
- Neuroinflammation and Neurodegeneration Mechanisms
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Traditional Chinese Medicine Studies
- Olfactory and Sensory Function Studies
- Traditional Chinese Medicine Analysis
- Toxin Mechanisms and Immunotoxins
- Rheumatoid Arthritis Research and Therapies
- Memory and Neural Mechanisms
- Circadian rhythm and melatonin
- Neurosurgical Procedures and Complications
- Infectious Encephalopathies and Encephalitis
- Alzheimer's disease research and treatments
- Cerebrospinal fluid and hydrocephalus
- Neonatal and fetal brain pathology
- Antiplatelet Therapy and Cardiovascular Diseases
Yunnan University of Traditional Chinese Medicine
2024-2025
Yunnan University
2022-2024
Affiliated Hospital of Taishan Medical University
2018-2024
Shandong First Medical University
2024
Background: Rheumatoid arthritis (RA) is an erosive-destructive inflammation of the joints, and chronic, long-term stiffness deformation induced by RA are some symptoms that difficult to treat. Dexamethasone (DEX) melittin (MLT) two interesting anti-inflammatory substances, both which possess effects exerted through suppression immune system. The purpose this study was explore role MLT in treatment DEX as well clarify influence on efficacy side DEX. Method: rats were injected with Complete...
Xiangqin Jiere granules (XQJRG) is a proprietary Chinese medicine treating children's colds and fevers, but its mechanism of action unclear. The aim this study was to explore the antipyretic mechanisms XQJRG based on pharmacodynamics, non-targeted metabolomics, network pharmacology, molecular biology experiments, docking, dynamics (MD) simulation. Firstly, yeast-induced fever model constructed in young rats effect XQJRG. Metabolomics pharmacology studies were performed identify key...
Alzheimer's disease (AD) stands as a neurodegenerative disorder causing cognitive decline, posing significant health concern for the elderly population in China. This study explored effects of outer membrane vesicles (OMVs) from gut microbiota AD patients on learning and memory abilities Tau protein phosphorylation mice. In contrast to OMVs healthy controls PBS treatment group, mice treated with AD-OMVs exhibited notable declines capabilities, evidenced by results Morris water maze, Y-maze,...
Royal jelly acid (10-HDA), an unsaturated fatty unique to royal jelly, exhibits a diverse range of biological activities, including hypoglycemic, anti-inflammatory, and anticancer properties. In recent years, the increasing demand for natural product supplements as health enhancers has led significant rise in consumption products daily wellness. Consequently, market expanded considerably. Understanding mechanisms underlying activities is crucial optimizing its therapeutic applications...
Xiangqin Jiere Granules (XQJRG), a Chinese patent medicine used to treat acute fever in children caused by colds, seasonal flu, and coronavirus disease 2019 has been proven have antipyretic anti-inflammatory effects young febrile rats. Fever is known affect the host-gut microbiota crosstalk. However, pharmacological mechanism of XQJRG this regard remains unclear.
To identify the risk factors contributing to cerebral microbleeds (CMBs), analyze correlation between quantity and distribution of CMBs overall cognitive performance, including specific domains in patients, investigate underlying mechanisms by which impact function.
Our aim was to study the character of quantitative EEG viral encephalitis.Collect data hospitalized children with encephalitis diagnosed by pediatricians from January 2013 September 2016, and normal cases at same age were control group. Using analysis technologies obtain power spectrum value, 1 12 21 value. Relative values 2 obtained calculation. All divided into 5 groups according character: 3 group, 4 5-6 7-9-year 10-14-year Viral group statistically compared characters encephalitis.Power...