Autoimmune thyroid disease (AITD) has been associated with adverse pregnancy outcomes in subfertile women spontaneous and assisted reproductive technology-induced pregnancies. The underlying pathophysiology is still elusive an association dysfunction or other infertility causes discussed. However, whether autoimmunity (TAI) per se a negative impact on female fertility not yet clarified. In this study, we investigated TAI healthy undergoing intracytoplasmic sperm injection (ICSI) for male may...

The role of Chlamydia (C.) trachomatis in male infertility is controversial. objective this study was to determine the prevalence asymptomatic C. infections partners infertile couples, and compare result with presence chlamydial antibodies serum semen. C.trachomatis detected five 50 semen specimens (10%) by either polymerase chain reaction for DNA or direct probing rRNA. There no association between detection Chlamydial were neither associated antiserum nor pathological standard parameters....

We tested whether the bacterial biofilm typical for vaginosis (BV) can be found on desquamated epithelial cells in cryopreserved donor semen. Bacteria were detected with FISH. Bacterial biofilm, covering layer vaginal biopsies of 20 women BV, was evaluated urine these same and their male partners (N=20) compared randomly selected semen samples (N=20). Urine from healthy laboratory clinic personnel used as controls. Desquamated covered a polymicrobial Gardnerella identified all BV 13 none...

An age-dependent increase in ribosomal DNA (rDNA) methylation has been observed across a broad spectrum of somatic tissues and the male mammalian germline. Bisulfite pyrosequencing (BPS) was used to determine levels rDNA core promoter upstream control element (UCE) along with two oppositely genomically imprinted genes (PEG3 GTL2) individual human germinal vesicle (GV) oocytes from 90 consenting women undergoing fertility treatment because infertility. Apart few (4%) single imprinting defects...

The association between 60 kDa Chlamydia trachomatis heat shock protein (CHSP60) antibodies and the etiology outcomes of in vitro fertilization (IVF) is not well known.A retrospective study with a double-blind analysis follicular fluid from 253 IVF patients for IgG to CHSP60.The CHSP60 were detected 74.1% women without embryo implantation 47.9% 1-3 implantations per cycle (P = 0.0004). 69.5% tubal occlusion 49.7% other causes infertility 0.01). antibody detection was unrelated maternal age,...

Purpose This study aims to investigate how the open discussion of infertility-related topics on public social media platforms contributes well-being individuals affected by infertility. Design/methodology/approach For this study, authors used a netnographic approach analyze 69 YouTube videos (>21 h raw data) produced infertility vloggers and more than 40,000 user comments. Findings The identify two ways in which patients benefit from discussions topic media: through watching engaging...

The past several decades have seen alarming declines in the reproductive health of humans, animals and plants. While humans introduced numerous pollutants that can impair systems (such as well-documented endocrine disruptors), potential for microplastics (MPs) to be contributing widespread fertility is particularly noteworthy. Over same timespan began documented, there has been a correlated shift towards “throw-away society” characterised by excessive consumption single-use plastic products...

The aim of this study was to evaluate the prevalence serum immunoglobulin (Ig)G and IgA antibodies recombinant chlamydial 60 kDa heat shock protein (C-hsp60) assess IgG 70 (C-hsp70) in Chlamydia-associated chronic salpingitis and/or isthmica nodosa with tubal occlusion. Infertile patients (n =34) Chlamydia-associated, histologically documented bilateral occlusions (group I) were compared infertile = 19) without II). antigen endocervical, urethral urine samples low both groups. median...

The COP1/SPA complex is an E3 ubiquitin ligase that acts as a key repressor of photomorphogenesis in dark-grown plants. While both COP1 and the four SPA proteins contain coiled-coil WD-repeat domains, differ from carrying N-terminal kinase-like domain not present COP1. Here, we have analyzed effects deletions missense mutations N-terminus SPA1 when expressed spa quadruple mutant background devoid any other proteins. Deletion large severely impaired activity transgenic plants with respect to...

The past several decades have seen alarming declines in the reproductive health of humans, animals and plants. While humans introduced numerous pollutants that can impair systems (such as well-documented endocrine disruptors), potential for microplastics (MPs) to be contributing widespread fertility is particularly noteworthy. Over same timespan began documented, there has been a correlated shift towards “throw-away society” characterised by excessive consumption single-use plastic products...

Abstract Smoking of classic cigarettes has been well-established as a health risk factor, including cardiovascular, neurological, and pulmonary diseases. Adverse effects on human reproduction have also shown. Smokers are assumed to significantly lower chance pregnancy, however, the impact smoking medically assisted (MAR) treatment outcomes is controversial. Moreover, habits changed during last decades since e-cigarettes hookahs, or water pipes, become very popular, yet little known regarding...

When cells are subjected to various stress factors, they increase the production of a group proteins called heat shock (hsp). Heat highly conserved present in organisms ranging from bacteria man. enable survive adverse environmental conditions by preventing protein denaturation. Thus physiological and pathological potential hsps is enormous has been studied widely over past two decades. The presence or absence influences almost every aspect reproduction. They among first produced during...