Abstract Ground waters are increasingly vulnerable to pollution by organic chemicals that migrate through the soil mantle. To assess minimal protection can be expected provide ground water, transport and fates of 13 pollutants were studied in a sandy with low matter content (0.087% C). Glass columns packed depth 140 cm manner preserved maximum extent possible characteristics original profile. In separate experiments, received 14 cm/day water containing mixture approximately 1.0 or 0.2...

We related serum nicotine and cotinine levels while subjects were smoking their usual numbers of cigarettes to wearing a patch under carefully controlled, smoke-free conditions in clinical research center. Twenty-four volunteers who needed intensive treatment for severe dependence admitted the center treated with 22 mg transdermal each day an smoking-cessation program. Serum levels, withdrawal symptoms, hours quality sleep noted. The steady-state produced lower than those observed when...

Cardiac troponin I (cTnI) is a highly specific marker that elevated in the blood for several days following myocardial infarction. The lactate dehydrogenase (LD) isoenzyme 1 to 2 ratio (LD1/LD2) established late diagnosis of In this study, sensitivity cardiac and LD1/LD2 were compared as markers injury over 5-day period 36 patients admitted with infarction coronary care unit. Over period, cTnI was significantly greater than (P < .05). concurrent elevation both five day range from 53.1%...

Interference studies of four glucose meters (Nova Biomedical [Waltham, MA] StatStrip [hospital grade], Roche Diagnostics [Indianapolis, IN] Accu-Chek Aviva [home Abbott Diabetes Care [Alameda, CA] Precision FreeStyle Freedom and LifeScan [Milpitas, SureStep Flexx grade]) were evaluated compared to the clinical laboratory plasma hexokinase reference method (Roche Hitachi 912 chemistry analyzer). These chosen reflect continuum care from hospital home grade commonly seen in North...

Abstract Context.—To assist with patient diagnosis and management, physicians from pain services, drug treatment programs, the emergency department frequently request that urine be tested for drugs of abuse. However, immunoassays abuse have limitations. Objective.—To use data College American Pathologists Proficiency Testing Surveys to determine summarize characteristics, performance, limitations Design.—Six years testing proficiency surveys were reviewed. Results.—Lysergic acid diethylamide...

Laboratory tests referred to outside facilities (ie, referred-out tests) represent a significant expense and may be more likely ordered inappropriately by health care professionals. We report the results of laboratory intervention designed reduce number simultaneously improve clinical utility tests. This was performed at Calgary Services, sole provider testing for 1.3 million residents Calgary, Alberta, Canada, its surrounding areas. For every test costing than $20 Canadian, we sent ordering...

Abstract Context.—To assist with patient diagnosis and management, physicians from pain services, drug treatment programs, the emergency department frequently request that urine be tested for drugs of abuse. However, immunoassays abuse have limitations. Objective.—To use data College American Pathologists Proficiency Testing Surveys to determine summarize characteristics, performance, limitations Design.—Six years testing proficiency surveys were reviewed. Results.—Lysergic acid diethylamide...

Historical research on pathology and laboratory medicine services in World War I has been limited. In the Spanish American War, these efforts were primarily focused tropical diseases. problems that could be addressed by strikingly different because of new field clinical pathology. Geographic differences, changing war tactics, trench warfare created issues.To describe scope value brought to effort.Available primary secondary sources related Expeditionary Forces' analyzed contrasted with...

c Oncocytic schneiderian papillomas (OSPs) are uncommon benign neoplasms that arise from the sinonasal epithelium. Malignancies arising in OSPs rare, and, to our knowledge, only 14 such instances have been reported medical literature. We report 2 additional cases—a small cell carcinoma and a undifferentiated presenting synchronously with neoplasm. The potential for malignant transformation is small, but warrants these be completely excised exclude coexisting carcinoma. (Arch Pathol Lab Med....

A conventional soil-solution sampler was modified to prevent loss of volatiles, which tend escape from the liquid sample during collection. The is connected a purging chamber, in turn trap packed with Tenax resin. collected by applying vacuum downstream end trap. Material that volatilizes collection aqueous captured on remains purged solution N2 and same then returned laboratory for desorption determination individual pollutants methods volatile organic analysis.

Multiple sclerosis is a severe demyelinating disease, the diagnosis of which aided by biochemical tests, such as detection oligoclonal immunoglobulin bands in cerebrospinal fluid (CSF). Because interpretation agarose gel electrophoresis (AGE) CSF for often equivocal, we compared immunofixation (IFE) with AGE 124 consecutive specimens submitted to Parkland Memorial Hospital Clinical Chemistry Laboratory (Dallas, Tex) bands. Both methods used Paragon Electrophoresis Systems (Beckman...

Approaches to determining optimal locations for patient service centers (phlebotomy clinics) have not been addressed in the published literature. Using city of Calgary, Alberta, Canada, as a test case, our objective is present novel method underserviced geographic areas within guide choice potential new center locations.Data on travel distances 198,883 phlebotomy visits well population data from 2011 Canada Census were used this study. geospatial mapping techniques, we produced maps showing...

A rapid method for measuring nicotine concentration in serum and urine is described. Deuterated used as an internal standard. Nicotine deuterated are extracted using a copolymeric-bonded phase silica column. The extract analysed by gas chromatography coupled with mass spectrometry (GC/MS) operating selected ion monitoring mode. has lower limit of detection approximately 2 micrograms/L linear to at least 2000 micrograms/L. Within-run percentage coefficients variation (% CV) < 4 both assays...

High-resolution serum protein electrophoresis (SPE) provides a clearer separation of β1- and β2-globulins than does low-resolution SPE. Currently, immunofixation (IFE) is performed in most laboratories based on high clinical suspicion disease associated with monoclonal gammopathy or an abnormality the pattern displayed electrophoretogram. The aim this study was to prospectively determine utility performing IFE specimens increased high-resolution SPE but normal electrophoretic visual...