Samir Qurashi

ORCID: 0009-0001-9731-8212
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About
Contact & Profiles
Research Areas
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Chronic Myeloid Leukemia Treatments
  • Macrophage Migration Inhibitory Factor
  • Structural Behavior of Reinforced Concrete
  • Acute Myeloid Leukemia Research
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Cytokine Signaling Pathways and Interactions
  • Lymphoma Diagnosis and Treatment

NGM Biopharmaceuticals (United States)
2022-2024

Solid tumors are dense three-dimensional (3D) multicellular structures that enable efficient receptor-ligand trans interactions via close cell-cell contact. Immunoglobulin-like transcript (ILT)2 and ILT4 related immune-suppressive receptors play a role in the inhibition of myeloid cells within tumor microenvironment. The relative contribution ILT2 to immune context solid tissue has not been fully explored. We present evidence both contribute inhibition. found although inhibits cell...

10.1158/2326-6066.cir-23-0568 article EN Cancer Immunology Research 2024-02-23
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