Jiawei Huang
A5042972765- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Chronic Myeloid Leukemia Treatments
- Macrophage Migration Inhibitory Factor
- Cancer Research and Treatments
- Immune Cell Function and Interaction
- Cell Adhesion Molecules Research
- Plant Virus Research Studies
- Structural Behavior of Reinforced Concrete
- Plant and Fungal Interactions Research
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Melanoma and MAPK Pathways
- Peptidase Inhibition and Analysis
- Immune cells in cancer
- Monoclonal and Polyclonal Antibodies Research
- Cytomegalovirus and herpesvirus research
- Acute Myeloid Leukemia Research
- Phagocytosis and Immune Regulation
- Herpesvirus Infections and Treatments
- CAR-T cell therapy research
- Plant Disease Resistance and Genetics
- Plant Pathogenic Bacteria Studies
- Bamboo properties and applications
- Myasthenia Gravis and Thymoma
- Transport and Logistics Innovations
Nanjing Medical University
2025
Nanjing University
2025
Nanjing General Hospital of Nanjing Military Command
2025
NGM Biopharmaceuticals (United States)
2024
Yunnan Institute of Tropical Crops
2021-2022
University of California, Irvine
2015
Tobacco Research Institute
2011
We recently reported that resistance to PD-1 blockade in a refractory lung cancer-derived model involved increased collagen deposition and the collagen-binding inhibitory receptor leukocyte-associated immunoglobulin-like 1 (LAIR1). Thus, we hypothesized LAIR1 cooperated suppress therapeutic response. In this study, report is associated with tumor stroma highly expressed by intratumoral myeloid cells both human tumors mouse models of cancer. Stroma-associated exhibit suppressive phenotype...
The HSV type 1 tegument virion phosphoprotein (VP) 11/12 (VP11/12) is a major Ag targeted by CD8(+) T cells from HSV-seropositive individuals. However, whether and which VP11/12 epitope-specific play role in the "natural" protection seen seropositive healthy asymptomatic (ASYMP) individuals (who have never had clinical herpes disease) remain to be determined. In this study, we used multiple prediction computer-assisted algorithms identify 10 potential HLA-A*02:01-restricted cell epitopes...
Purpose.: A clinical vaccine that protects from ocular herpes simplex virus type 1 (HSV-1) infection and disease still is lacking. In the present study, preclinical trials of nine asymptomatic (ASYMP) peptides, selected HSV-1 glycoproteins B (gB), tegument proteins VP11/12 VP13/14, were performed in “humanized” HLA–transgenic rabbit (HLA-Tg rabbit) model herpes. We recently reported these peptides are highly recognized by CD8+ T cells “naturally” protected HSV-1–seropositive healthy ASYMP...
Solid tumors are dense three-dimensional (3D) multicellular structures that enable efficient receptor-ligand trans interactions via close cell-cell contact. Immunoglobulin-like transcript (ILT)2 and ILT4 related immune-suppressive receptors play a role in the inhibition of myeloid cells within tumor microenvironment. The relative contribution ILT2 to immune context solid tissue has not been fully explored. We present evidence both contribute inhibition. found although inhibits cell...
In Guangxi Province of southwest China, diseases caused by Tospoviruses (family Bunyaviridae) pose a serious threat to tobacco (Nicotiana tobacum) production. During surveys conducted annually at Xinrong Village in Jingxi County from 2008 2010, more than 130 ha fields were found have 10 50% plants exhibiting symptoms similar spotted wilt Tomato virus (TSWV). this period, disease prevalence and incidence also Fushan, Debao most the cultivars produced these areas, including Yunyan 85, 87, 92,...
Chilli pepper is an important economic crop and virus diseases are constraints on its production. In 2018, disease surveys were conducted at a 15-ha chilli plantation in Dehong, southwest of Yunnan Province, China. Throughout the growing season from March to September, plants developed three different virus-like symptoms leaves, including mosaic, yellow mottle shrinkage (Fig. S1). Based observation symptomatic phenotypes, field indicated that incidence ranged 30% peak 100% July, resulting...
Abstract The present study described molecular characterization of two potyviruses: wild tomato mosaic virus Dehong isolate (WTMV‐Dh) and chilli veinal mottle (ChiVMV‐Dh) mix‐infection pepper assessed their on pepper. Transcriptome next‐generation sequencing technology (NGS) RT‐PCR were used to obtain the complete genome sequences abovementioned viruses. results showed that sequence WTMV‐Dh is 9675 nucleotides (nt) in length encodes a polyprotein 3075 amino acids (aa). shares 76.1%–82.6% nt...
<p>Supplementary Methods, Tables, and Figure Legends</p>
<p>Supplementary Figure S5</p>
<p>Supplementary Figure S8</p>
<p>Supplementary Methods, Tables, and Figure Legends</p>
<p>Supplementary Figure S4</p>
<p>Supplementary Figure S9</p>
<p>Supplementary Figure S4</p>
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<p>Supplementary Figure S9</p>
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<p>Supplementary Figure S8</p>
<p>Supplementary Figure S5</p>
<p>Supplementary Figure S6</p>
<p>Supplementary Figure S10</p>