Lin hui Xu

ORCID: 0009-0001-9765-9770
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About
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Research Areas
  • DNA Repair Mechanisms
  • Cancer-related Molecular Pathways
  • Medical Imaging Techniques and Applications
  • RNA modifications and cancer
  • Radiomics and Machine Learning in Medical Imaging
  • Digital Radiography and Breast Imaging

Yangzhou University
2023

We previously described a nucleolar protein RSL1D1 but distributed throughout the nucleus in HCT116 colorectal cancer (CRC) cells to facilitate G1/S transition by inhibiting p53 signaling. Here, we found another protein, programmed cell death 11 (PDCD11), also with an "Extra-nucleolar" localization CRC regulate G2/M checkpoint. This directly interacts and HDM2 nucleoplasm, thereby recruiting for ubiquitination degradation. The ensuing downregulation of increases CDK1 level help pass Upon DNA...

10.1038/s41389-023-00501-2 article EN cc-by Oncogenesis 2023-12-07

Objective To evaluate the diagnostic value of full-field digital mammography for breast cancer. Methods The clinical data and mammograms 230 patients with diseases between January 2008 July were collected reviewed. Craniocaudal (CC) mediolateral oblique (MLO) view performed in all before surgery. Three experienced radiologists imaging assessment analyzed classified according to reporting system (BI-RADS). sensitivity, specificity accuracy evaluated their pathological diagnosis. reasons...

10.3760/cma.j.issn.0253-3766.2009.11.012 article EN 2009-11-01
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