A5011569410- Mycotoxins in Agriculture and Food
- Probiotics and Fermented Foods
- Gut microbiota and health
- Wheat and Barley Genetics and Pathology
- Animal Nutrition and Physiology
- Synthesis and bioactivity of alkaloids
- Silymarin and Mushroom Poisoning
- Allergic Rhinitis and Sensitization
- Healthcare and Venom Research
- Biopolymer Synthesis and Applications
- Enzyme-mediated dye degradation
- Agricultural safety and regulations
- Tryptophan and brain disorders
- Bladder and Urothelial Cancer Treatments
- Diet and metabolism studies
- vaccines and immunoinformatics approaches
- Pesticide and Herbicide Environmental Studies
- Natural product bioactivities and synthesis
- Contact Dermatitis and Allergies
- Food Allergy and Anaphylaxis Research
- Proteoglycans and glycosaminoglycans research
- Essential Oils and Antimicrobial Activity
- Carcinogens and Genotoxicity Assessment
- Biological and pharmacological studies of plants
- Listeria monocytogenes in Food Safety
Feed Research Institute
2023-2025
Chinese Academy of Agricultural Sciences
2023-2025
Ministry of Agriculture and Rural Affairs
2023-2025
Beijing Institute of Petrochemical Technology
2025
Gansu Agricultural University
2021
The co-occurrence of aflatoxin B1 (AFB1) and zearalenone (ZEN) in grain-based food animal feed poses significant health risks to humans animals due their potent mutagenic, cytotoxic, carcinogenic properties. Conventional physical chemical methods are insufficient for effectively detoxifying multiple mycotoxins present feed. In this study, we evaluated the capability Bacillus subtilis ZJ-2019-1 (B. ZJ-2019-1) simultaneously degrade AFB1 ZEN while optimizing reaction enhance degradation...
Lactobacilli have played an important role in the gut health of pets. The aim this research was to study effects isolated (named L11) on immune, nutrient metabolism, and cats. Twelve healthy adult cats were randomly assigned into two groups, control group (CONTROL, n = 6, without any probiotics product) treatment (probiotics, L11 109 CFU/kg feed), while using same dry diet. On day 28, blood fecal samples collected, biochemical indices, microbiota, short-chain fatty acids (SCFAs),...
ABSTRACT Polyvinyl alcohol (PVA) hydrogels have been extensively utilized in cartilage repair due to their hydrophilicity and superior biocompatibility. However, achieving materials with optimal mechanical, structural, biological properties has remained challenging. In this study, multiple groups of composite were prepared using PVA, chitosan, agarose via a freeze–thaw cycle method, performances comprehensively evaluated. We identified that hydrogel consisting 15 wt% 1.5 1 possessed porous...
Lactic acid bacteria play a crucial role in maintaining the health of host’s gut microbiota. In this study, anti-inflammatory properties Limosilactobacillus reuteri LR20-6 and Lacticplantibacillus plantarum L272 were evaluated using mouse model diarrhea induced by Escherichia coli. We also investigated their effects on microbiota regulation. The results indicated that both could reduce inflammation inhibiting expression inflammatory factors IL-6 TNF-α blocking MyD88 NF-kB/p65 signaling...
To investigate the anti-bacterial and anti-inflammatory properties of sophoridine elucidate its mechanism action, we carried out both in vitro vivo experiments. Multiple bacterial strains were utilized to determine effective concentration antibacterial bactericidal assays. Subsequently, LPS-stimulated RAW264.7 cells E. coli-challenged BALB/c mice models employed evaluate production inflammatory cytokines. Our results showed that concentrations exceeding 5.12 mg/mL significantly inhibited...
A large number of cases infectious colitis caused by multidrug-resistant (MDR) bacteria, such as Escherichia coli, can result in colon damage and severe inflammation. Vanilla, a widely utilized flavor fragrance compound, is extensively used various food. However, the effect vanilla on MDR E. coli-induced has received less attention. In this study, antibacterial activity vanillin against coli other bacteria was determined microtiter broth dilution method. The antioxidant anti-inflammatory...
<title>Abstract</title> Aflatoxin B1 (AFB1) and zearalenone (ZEN) are the most prevalent mycotoxins in production, posing a serious threat to food feed industry resulting substantial economic burden. Therefore, finding safe efficient method for biodegradation of is utmost important addressing this issue. <italic>Bacillus subtilis</italic> ZJ-2019-1, capable degrading AFB1 ZEN, was isolated cultured our laboratory vitro. In study, we conducted detoxification tests on ZEN using <italic>B....
The global prevalence of aflatoxin B1 (AFB1) and zearalenone (ZEN) contamination in food feed poses a serious health risk to humans animals. Recently, enzymatic detoxification has received increasing attention, yet most enzymes are limited degrading only one type mycotoxin, free often exhibit reduced stability activity, limiting their practicality real-world applications. In this study, the laccase
Fumonisins (FBs), particularly fumonisin B1 (FB1) and B2 (FB2) produced mainly by
Cirsium japonicum, a traditional herb, exhibits significant anti-inflammatory activity; however, the main components and potential mechanisms of C. japonicum remain unclear. The aim this study is to investigate mechanism through network pharmacology cellular experiments. effective targets for activity were identified using Chinese medicine systematic database, TCMSP analysis platform, GeneCards database. drug-component-target-disease diagram was constructed Cytoscape3.8.0 software, while...
Cirsium japonicum, a traditional herb, exhibits significant anti-inflammatory activity. However, the main components and potential mechanisms of C. japonicum remain unclear. The aim this study is to investigate mechanism through network pharmacology cellular experiments. effective targets for activity were identified using Chinese medicine systematic database, TCMSP analysis platform, GeneCards database. drug–component–target–disease diagram was constructed Cytoscape 3.8.0 software, while...
Zearalenone (ZEN) has been detected in both pet food ingredients and final products, causing acute toxicity chronic health problems pets. Therefore, the early detection of mycotoxin contamination is crucial for ensuring safety well-being animals. This study aims to develop a rapid cost-effective method using an electronic nose (E-nose) machine learning algorithms predict whether ZEN levels exceed regulatory limits (250 µg/kg), as set by Chinese legislation. A total 142 samples from various...
Objectives: The purpose of this study was to find the potential mechanism two Lactobacillus (Lactobacillus plantarum L11 and reuteri LR) on ameliorating obesity, including lipid metabolism gut microbiota. isolates have been studied good characterization in vitro, but vivo studies modulating microbiota were not studied. Methods: In study, mice with HFD supplemented or LR exhibited slower obesity progression, reduced weight gain, abdominal fat accumulation, liver damage, inflammation, adipose...