A5022184579- High voltage insulation and dielectric phenomena
- Power Transformer Diagnostics and Insulation
- Bacterial biofilms and quorum sensing
- Monoclonal and Polyclonal Antibodies Research
- Antimicrobial Resistance in Staphylococcus
- Diverse Aspects of Tourism Research
- Remote Sensing and Land Use
- Antimicrobial Peptides and Activities
- Geotourism and Geoheritage Conservation
- Forest, Soil, and Plant Ecology in China
- Complex Network Analysis Techniques
- Natural product bioactivities and synthesis
- Environmental Changes in China
- Mycotoxins in Agriculture and Food
- Biosimilars and Bioanalytical Methods
- Geomechanics and Mining Engineering
- Environmental Quality and Pollution
- Public Relations and Crisis Communication
- Tryptophan and brain disorders
- Chronic Lymphocytic Leukemia Research
- Environmental Impact and Sustainability
- Simulation and Modeling Applications
- Geology and Paleoclimatology Research
- Gut microbiota and health
- Silymarin and Mushroom Poisoning
Ministry of Agriculture and Rural Affairs
2024-2025
Northwest Institute of Mechanical and Electrical Engineering
2024-2025
Feed Research Institute
2024-2025
Shenyang Pharmaceutical University
2024-2025
Chinese Academy of Agricultural Sciences
2024-2025
Northwest A&F University
2024-2025
Guizhou Provincial People's Hospital
2022-2025
Guiyang Medical University
2025
Nanjing University
2020-2024
Nanjing Agricultural University
2016-2024
Astragalin (AG), a typical flavonoid found in Thesium chinense Turcz (T. chinense), is abundant various edible plants and possesses high nutritional value, as well antioxidant antibacterial effects. In this study, we initially predicted the mechanism of action AG with two anti-aging antioxidant-related protein targets (CD38 IGFR) by molecular docking dynamics simulation techniques. Subsequently, examined effects Caenorhabditis elegans (C. elegans), zebrafish, verified related mechanisms. C....
Soil alkalinity is a major abiotic constraint to crop productivity and quality. Wild soybean (Glycine soja) considered be more stress-tolerant than cultivated (G. max), has considerable genetic variation for increasing tolerance of soybean. In this study, we analyzed the transcriptome profile in roots an tolerant wild variety N24852 at 12 24 h after 90 mM NaHCO3 stress by RNA-sequencing. Compared with controls, total 449 differentially expressed genes (DEGs) were identified, including 95 140...
Abstract Background Our recent studies have identified that the red nucleus (RN) dual-directionally modulates development and maintenance of mononeuropathic pain through secreting proinflammatory anti-inflammatory cytokines. Here, we further explored action IL-33 in early pain. Methods In this study, male rats with spared nerve injury (SNI) were used as model. Immunohistochemistry, Western blotting, behavioral testing to assess expressions, cellular distributions, actions its related...
Due to its ability form biofilms on medical devices, Staphylococcus epidermidis has emerged as a major pathogen of nosocomial infections. In this study, we investigated the role two-component signal transduction system ArlRS in regulating S. biofilm formation. An ArlRS-deficient mutant, WW06, was constructed using strain 1457 parental strain. Although growth curve WW06 similar that SE1457, mutant unable vitro. rabbit subcutaneous infection model, sterile disks made polymeric materials were...
Methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant S. aureus, is a leading cause of community and hospital associated infections globally. In this work, we found that deletion the arlRS two-component system genes in USA300 USA500 strains resulted increased susceptibilities to oxacillin (8-16-fold decrease minimal inhibitory concentrations). USA300ΔarlRS, transcriptional levels mecA or blaZ showed no obvious change, while mRNA spx 4-fold at 4 h 6.3-fold 10...
Abstract Staphylococcus aureus is a common pathogen in chronic rhinosinusitis (CRS) patients, the pathogenesis of which involves ability to form biofilms and produce various virulence factors. Tobacco smoke, another risk factor CRS, facilitates S. biofilm formation; however, mechanisms involved are unclear. Here, we studied effect nicotine on formation expression virulence-related genes. strains isolated from CRS patients USA300 strain were treated with or untreated (control)....
To investigate the anti-bacterial and anti-inflammatory properties of sophoridine elucidate its mechanism action, we carried out both in vitro vivo experiments. Multiple bacterial strains were utilized to determine effective concentration antibacterial bactericidal assays. Subsequently, LPS-stimulated RAW264.7 cells E. coli-challenged BALB/c mice models employed evaluate production inflammatory cytokines. Our results showed that concentrations exceeding 5.12 mg/mL significantly inhibited...
Herein, we present a redox-relay strategy that enables the nickel-catalyzed, atom-economical coupling of isatins and allyl alcohols. This reaction is notable for its lack requirement additional ligands or reducing agents, minimal catalyst usage (only 1%), thus meeting principles green chemistry. Mechanistic studies have shown alcohols act as both reductants precursors α,β-unsaturated ketones in reaction.
Yogurt and postbiotics are both beneficial for intestinal health of pets. This study was conducted to investigate the effects yogurt with in cats. A total 18 adult cats were randomly divided into three groups, CK group (Control n = 6, free feeding drinking without any probiotic products), Y (Yogurt, 50 g/day), YP (Yogurt + 2% postbiotics, same environment diet. On 21st day, blood fecal samples collected tested biochemical indices, immunological parameters, inflammatory factors, flora,...
Lactic acid bacteria play a crucial role in maintaining the health of host’s gut microbiota. In this study, anti-inflammatory properties Limosilactobacillus reuteri LR20-6 and Lacticplantibacillus plantarum L272 were evaluated using mouse model diarrhea induced by Escherichia coli. We also investigated their effects on microbiota regulation. The results indicated that both could reduce inflammation inhibiting expression inflammatory factors IL-6 TNF-α blocking MyD88 NF-kB/p65 signaling...
Epigallocatechin gallate (EGCG) is a main constituent of green tea polyphenols that are widely used as food preservatives and considered to be safe for consumption. However, the underlying antimicrobial mechanism EGCG bacterial response not clearly understood. In present study, genome-wide transcriptional analysis typical spoilage bacterium, Pseudomonas fluorescens responded was performed using RNA-seq technology. A total 26,365,414 23,287,092 clean reads were generated from P. treated with...