A5068006902- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Drug-Induced Adverse Reactions
- Mast cells and histamine
- Tissue Engineering and Regenerative Medicine
- Glaucoma and retinal disorders
- Electrospun Nanofibers in Biomedical Applications
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Mesenchymal stem cell research
- Cardiovascular and Diving-Related Complications
- Cerebrovascular and genetic disorders
- Advancements in Transdermal Drug Delivery
- Congenital heart defects research
- Mitochondrial Function and Pathology
- Urticaria and Related Conditions
- Contact Dermatitis and Allergies
- Clusterin in disease pathology
- High Altitude and Hypoxia
- COVID-19 Impact on Reproduction
- Maternal Mental Health During Pregnancy and Postpartum
- Gestational Diabetes Research and Management
L V Prasad Eye Institute
2020-2024
Manipal Academy of Higher Education
2023-2024
All India Institute of Medical Sciences Bhopal
2023
All India Institute of Medical Sciences Raipur
2023
All India Institute of Medical Sciences
2023
College of Medical Sciences
1967
Banaras Hindu University
1967
Corneal scarring and opacification are a significant cause of blindness affecting millions worldwide. The current standard care for corneal is transplantation, which suffers from several drawbacks. One alternative approach that has shown promise the use xenogeneic extracellular matrix (ECM), but its clinical applicability challenging due to safety concerns. This study reports innovative human cornea-derived ECM prevent post-traumatic scarring. About 30 - 40% corneas donated eye banks do not...
Corneal scarring is one of the major causes blindness, affecting millions worldwide. Despite recent advancements in surgical strategies, there an unmet need for a clinically feasible material and methods to prevent following corneal injury. In this study, we report potential utility hydrogel derived from cadaveric animal corneas, using decellularized matrix (abbreviated as dCMH), which prepared by simple method. This easily injectable, biocompatible, has ability maintain good shape-retention...
Extraction of tear protein from Schirmer's strip is a prerequisite for the proper identification and screening biomarkers in dry eye disease. The study compares different methods extraction proteins strip.Reflex was collected healthy controls (HC; n = 12), Stevens-Johnson syndrome (SJS; 3) disease (DED; patients using capillary tube. This used to measure volume absorbed by per microliter. Different buffers (6) were compare yield four conditions. extracted highest buffer analyzed mass...
Mesenchymal stem cells (MSCs) have been proven to prevent and clear corneal scarring limbal cell deficiency. However, using animal-derived serum in a culture medium raises the ethical regulatory bar. This study aims expand characterize human limbus-derived stromal/mesenchymal (hLMSCs) for first time vitro xeno-free medium.Limbal tissue was obtained from therapeutic grade corneoscleral rims subjected explant till tertiary passage media with without (STEM MACS XF; SM), obtain pure hLMSCs....
This study aims to elucidate the tear proteome and understand underlying molecular mechanisms involved in ocular complications following Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN).
Biological materials derived from extracellular matrix (ECM) proteins have garnered interest as their composition is very similar to that of native tissue. Herein, we report the use human cornea decellularized ECM (dECM) microparticles dispersed in fibrin sealant an accessible therapeutic alternative for corneal anterior stromal reconstruction. dECM had good particle size distribution (≤10 µm) and retained majority components found Fibrin–dECM hydrogels exhibited compressive modulus 70.83 ±...
Abstract Background Congenital hereditary endothelial dystrophy (CHED) is a rare form of corneal caused by SLC4A11 gene variations. This study aims to find the genetic alterations in SLC4A11, two Indian familial CHED cases with affected members n = 3 and 2 respectively five sporadic using direct sequencing, followed silico analysis characterization identified variants. Results All three first family were novel homozygous c.1514C > G (p.Ser489Trp) variation while second showed presence...
Research Articles| July 17 2009 Histamine Skin Sensitivity and Blood in Patients with Urticaria Subject Area: Immunology Allergy D.N. Prasad; Prasad Departments of Pharmacology Medicine, College Medical Sciences, Banaras Hindu University, Varanasi Search for other works by this author on: This Site PubMed Google Scholar S.S. Gambhir; Gambhir Gurmohan Singh; Singh S.K. Bhattacharya; Bhattacharya P.K. Das International Archives Applied (1967) 31 (3): 230–238. https://doi.org/10.1159/000229872...
Background: Objective of study was to evaluate the effect prenatal yoga on maternal gestational weight gain (GWG) and psychological stress in pregnancy (PSS) labour outcomes. Methods: Prospective randomized controlled trial conducted at AIIMS, New Delhi between May 2020-December 2021. Sixty women each were recruited control group. Women group attended 60 minutes supervised sessions followed by self-sessions. received routine antenatal care along with 30 per day walking dietary counselling....
Abstract Background: Congenital hereditary endothelial dystrophy (CHED) is a rare form of corneal and known to be caused by SLC4A11 gene mutation. The purpose this study find genetic alterations in using direct sequencing two Indian familial CHED cases with affected members n=3 n=2 respectively five non-familial single member, followed silico characterization identified mutations. Results: All three the first family were novel hom. c.1514C>G (p.Ser489Trp) mutation while second showed...