A5092447327- Dermatological and COVID-19 studies
- Moyamoya disease diagnosis and treatment
- Neurological Disease Mechanisms and Treatments
- Gut microbiota and health
- Genital Health and Disease
- Macrophage Migration Inhibitory Factor
- Cerebrovascular and genetic disorders
- Body Contouring and Surgery
- Dementia and Cognitive Impairment Research
Nanjing Medical University
2023-2024
Wuxi People's Hospital
2023-2024
Background Cerebral small vessel disease (CSVD) is a cluster of microvascular disorders with unclear pathological mechanisms. The microbiota-gut-brain axis an essential regulatory mechanism between gut microbes and their host. Therefore, the compositional functional microbiota alterations lead to cerebrovascular pathogenesis. current study aims determine alteration clinical value in CSVD patients. Methods Sixty-four patients 18 matched healthy controls (HCs) were included our study. All...
As the pathogenesis of cerebral small vessel disease with cognitive impairment (CSVD-CI) remains unclear, identifying effective biomarkers can contribute to clinical management CSVD-CI. This study recruited 54 healthy controls (HCs), 60 CSVD-CI patients, and 57 CSVD cognitively normal (CSVD-CN) patients. All participants underwent neuropsychological assessments multimodal magnetic resonance imaging. Macrophage migration inhibitory factors (MIFs) were assessed in plasma. The least absolute...