A5009302904- Ovarian cancer diagnosis and treatment
- Inflammatory Bowel Disease
- Intraperitoneal and Appendiceal Malignancies
- Colorectal Cancer Treatments and Studies
- Extracellular vesicles in disease
- Adenosine and Purinergic Signaling
- Congenital Anomalies and Fetal Surgery
- Autophagy in Disease and Therapy
- Cancer Immunotherapy and Biomarkers
- Clinical Nutrition and Gastroenterology
- Endoplasmic Reticulum Stress and Disease
- Infant Nutrition and Health
- Calcium signaling and nucleotide metabolism
- Cancer, Stress, Anesthesia, and Immune Response
- Pancreatic function and diabetes
Centre de Recherche sur l'Inflammation
2019-2023
Centre National de la Recherche Scientifique
2021-2023
Université Paris Cité
2020-2023
Inserm
2019-2023
Délégation Paris 7
2019
Sorbonne Paris Cité
2019
Hôpital Beaujon
2019
Assistance Publique – Hôpitaux de Paris
2019
Research Article30 April 2019Open Access Transparent process Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation Marion Maurel INSERM U1242, “Chemistry, Oncogenesis Stress Signaling”, University Rennes, France Centre de Lutte Contre le Cancer Eugène Marquis, VIB Department Medical Protein Research, UGent, Gent, Belgium Apoptosis Centre, School Natural Sciences, NUI Galway, Ireland Search for more papers by this author Joanna Obacz Tony...
Although appendectomy may reduce colorectal inflammation in patients with ulcerative colitis (UC), this surgical procedure has been suggested to be associated an increased risk of colitis-associated cancer (CAC). Our aim was explore the mechanism underlying appendectomy-associated CAC. Five-week-old male BALB/c mice underwent appendectomy, appendicitis induction, or sham laparotomy. They were then exposed azoxymethane/dextran sodium sulfate (AOM/DSS) induce Mice killed 12 weeks later, and...
Introduction: Immunity of colitis-associated colorectal cancer (CAC) differs fundamentally from that the sporadic form.The aim this study was to evaluate whether difference could potentiate efficacy immune-checkpoint inhibitor anti-PD1 against CAC.Methods: CAC tumorigenesis induced by azoxymethane (AOM) followed three cycles dextran sodium sulfate (DSS) in mice.Two weeks after end DSS, mice were treated with antibody (n=9) or isotype (n=9).The severity clinical and histological colitis,...
Abstract Objectives Necrotizing enterocolitis (NEC) is a severe neonatal surgical condition, associated with prolonged pro‐inflammatory state, leading to high mortality and morbidity rates. Carbon dioxide (CO 2 ) insufflation during laparoscopy may have an anti‐inflammatory effect. We aimed evaluate the effects of CO ‐insufflation on experimental colitis. Methods Acute colitis was induced in 6‐week‐old Balb/c mice by administration 2%‐dextran sulfate‐sodium (DSS) 7 days ( n = 45). On Day 4,...
Abstract Objective While appendectomy may reduce colorectal inflammation in patients with ulcerative colitis (UC), has been suggested to be associated an increased risk of colitis-associated cancer (CAC). The aim this study was explore the mechanism underlying appendectomy-associated CAC. Design Five-week-old male BALB/c mice underwent appendectomy, appendicitis induction or sham laparotomy. They were then exposed azoxymethane/dextran sodium sulfate (AOM/DSS) induce Mice sacrificed 12 weeks...