A5092906280- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
University Medical Center Hamburg-Eppendorf
2023-2025
Universität Hamburg
2023-2025
Computed tomography perfusion (CTP) imaging is regularly used to guide patient selection for mechanical thrombectomy (MT). However, the effect of MT in patients without salvageable tissue on CTP has not been investigated. The purpose this study was assess with stroke mismatch profiles. This observational analyzed ischemic consecutively treated between March 1, 2015, and January 31, 2022, triaged by multimodal-computed undergoing MT. lesion-core profiles were defined using a volume/ratio ≥10...
Mechanical thrombectomy (MT) is of benefit to patients with ischemic stroke; however, the effect recanalization on lesion pathophysiology not yet well understood. The aim this study was quantitatively assess how vessel clinical outcome mediated by edema reduction versus penumbra salvage.Consecutive analysis made anterior circulation stroke triaged multimodal computed tomography (CT) undergoing MT. Edema defined using difference quantitative net water uptake (NWU) determined baseline and...
In ischemic stroke, there is limited data regarding the impact of baseline hyperglycemia on treatment effect recanalization neurological recovery. This study aimed to directly compare-how short- and long-term serum glucose levels modify functional outcome in patients with stroke specifically analyze occurrence delayed recovery ("stunned brain phenomenon"). Observational retrospective analysis including anterior circulation large vessel occlusion undergoing mechanical thrombectomy following...
In ischemic stroke, the impact of short- versus long-term blood glucose level (BGL) on early lesion pathophysiology and functional outcome has not been assessed. The purpose this study was to directly compare effect (glycated hemoglobin [HbA1c]) serum BGL edema formation outcome.
Purpose: The Alberta Stroke Program Early CT Score (ASPECTS) is regularly used to guide patient selection for mechanical thrombectomy (MT). Similarly, penumbral imaging based on computed tomography perfusion (CTP) may serve as neuroimaging tool treatment. Yet, patients with a large ischemic core CTP show only minor changes resulting in high ASPECTS. Aim: We hypothesized twofold: (1) the treatment effect of vessel recanalization volume > 50 mL but ASPECTS ⩾ 6 not different compared <...
Introduction: Managing blood pressure in patients with large vessel occlusion affects infarct size and clinical outcomes. We examined how restoring flow impacts systemic during mechanical thrombectomy. Patients Methods: the anterior circulation undergoing thrombectomy between June 2016 January 2018 were screened. included those treated under local anesthesia or conscious sedation analyzed standardized protocols to assess systolic diastolic levels throughout procedure. The primary outcome was...