Abstract This study reports the prevalence and antibiotics resistance status of Salmonella detected in raw meat from Lahore, Pakistan. Overall, N = 111 samples, were collected local markets. was recovered 57 (51.35%) including 45.83% poultry, 60% buffalo, 64.28% cow, goat samples. The predominant strains enterica serovars; Typhimurium (45.4%), Typhi (27.2%), Enteritidis (18.1%), identified by VITEK system 16S rRNA gene sequencing. isolates exhibited high to Erythromycin (100%), Cefepime...

Background. Enterococci are a part of the natural intestinal flora humans and animals play an important role in keeping microbial balance gut. Many species also used as probiotics that produce vitamins, stimulate immune response, maintain integrity The use dietary supplements to reinforce some gut components is current aspect functional food sciences treat various diseases. Methodology. In study, 21 Enterococcus strains were isolated identified morphologically, biochemically,...

Background: Cerebrospinal fluid (CSF) leakage is a substantial complication that results from spinal dysraphism surgery, which contributes to prolonged hospital stays and increased morbidity rate. Objectives: This investigation was carried out ascertain the frequency of immediate postoperative CSF leakage, identify risk factors are associated with these leaks assess clinical outcomes in patients who undergoing surgery. Methods: From January December 2023, 40 underwent surgery for were...

Mitochondrial dysfunction triggered by increased reactive oxygen species (ROS) generation is involved in the pathogenesis and development of cardiac hypertrophy. Nanoceria (cerium oxide nanoparticle) has powerful ROS-scavenging properties considered a potential therapeutic option for curbing ROS-related disorders. Here, we explored signaling mechanism underlying protective effects nanoceria against angiotensin (Ang) II-stimulated pathological response H9c2 cardiomyoblasts. Our data revealed...

Studies have suggested that osteocalcin, a bone formation marker, is related to body metabolism and insulin sensitivity. Whether this relation mediated through an interaction with adipokines remains unclear. The aim of study was assess the effect weight loss on serum osteocalcin its three adipokines, adiponectin, chemerin, resistin. Forty-nine obese nondiabetic males completed four-month dietary program. Body mass index (BMI) decreased significantly from<mml:math...

(1) Background: Chronic rhinosinusitis (CRS) is a common chronic inflammation of the nasal mucosa and paranasal sinuses. The pathogenesis multifactorial and, as yet, not well understood. (2) Methods: Nasal lavage fluid samples were collected from patients diagnosed with sinusitis polyposis (CRSwNP) (n = 10) individuals without (control group) who had no complaints. In present study, we used an untargeted label-free LC-MS/MS mass spectrometric approach combined bioinformatics network pathway...

Salmonella is one of the most common causes foodborne diseases among humans worldwide. Animal-derived foods are frequently tested for presence spp. However, detection in meat and its products often hindered due to background normal flora, which may lead false-positive Salmonella. The present study aimed isolate accurately identify from poultry meat. For this purpose, seventy samples were collected Lahore, Pakistan, isolated on selective differential media, identified using biochemical tests...

Tonsillar carcinoma metastasis to the myocardium is undermined with detection rate often occurring at autopsy or advance stage. A 60-year-old male a 1-month history of right-sided facial pain and failed antibiotics therapy underwent head neck CT scan that revealed tonsillar mass. biopsy squamous cell carcinoma, HPV-16 positive. PET-CT showed significant activity in right mass along prominent level 2 lymph nodes no distant disease. Definite surgery was deferred he 7 weeks radiation concurrent...

Cave actinobacteria are relatively less explored and considered as the new targets for discovery of novel antimicrobials, specifically against highly resistant pathogens such extensively drug-resistant (XDR) Salmonella. In this study N=20 isolates were retrieved from least disturbed caves situated at Bahadurkhel Karak, Pakistan (33° 16’ 52” North, 70° 79’ 07” East) 15’ 90” 94’ 72” East). The identified using standard morphological biochemical characterization procedures well by 16S rDNA...

Vegetables are among the finest sources of high-quality nutrients including, carbohydrates, vitamins, fibers and minerals, having beneficial health effects. However consuming raw vegetables obtained from retailer shops renders them a reservoir pathogenic bacteria due to unhygienic production, storage, handling practices, could be major route antibiotics resistance dissemination. The present work aimed at evaluation fresh for total microbial load coliforms presence determination antibiotic...

Since the advent of COVID-19 pandemic in 2019, a mammoth research activity targeting etiological features has commenced. Many aspects disease have been studied, and various others are under consideration. The secondary microbial coinfections with generated some serious concerns across globe. This review mainly focuses on notable coinfections. coinfection influenza, tuberculosis, typhoid may mimic original symptoms. Physicians clinicians must focus which aggravate progression towards acute...

Monkeypox virus, a member of orthopoxviruses, has recently started to emerge in non-endemic countries worldwide, ringing the false alarms possible new epidemic as world is already fighting COVID-19 pandemic. However, there are some key differences nature these two infections that require understanding by public health authorities order keep masses safe from another psychological trauma, which been previously associated with SARS-CoV-2 primarily affects respiratory tract, whereas monkeypox...

Objective: The purpose of this study is to analyse the complication rate endoscopic third ventriculostomy for obstructive hydrocephalus. Study Design: Descriptive Place and Duration: This descriptive was conducted at Dow International Medical College Hospital OJHA Campus, Karachi in period from May, 2022 October, 2022. Methods: Total 97 male female patients aged 1-30 presented. Patients had hydrocephalus were included. With consent, all provided age, sex, BMI. CT brain MRI performed. In...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a global pandemic causing disease 2019 (COVID-19). It was firstly reported in Hubei province the People’s Republic of China and spread worldwide quickly. COVID-19 affects every person differently, from mild to life-threatening symptoms (Nawaz, 2020), along with other bacterial or fungal co-infections (CDC., 2021). affected patients are prone develop opportunistic infections (Salehi et al., 2020). immune system...

Background: Percutanoeous tracheotomy (PT) is a minimal invasive procedure alternative to surgical tracheotomy. PT offers an added advantage of enormous decrease time interval between decision doing and actually it. Moreover hazards patient transport can be avoided as it safely performed at the bedside. We started in 2003 100 cases using forceps dilatation. Later we switched over cone dilatation where 215 cases. This study aims compare two techniques vs. methods for PT. Methods: A total were...