A5017943937- Cancer Immunotherapy and Biomarkers
- Computational Drug Discovery Methods
- CAR-T cell therapy research
- Immunotherapy and Immune Responses
- Salmonella and Campylobacter epidemiology
- COVID-19 Clinical Research Studies
- Viral Infections and Vectors
- Health and Well-being Studies
- Phytochemicals and Antioxidant Activities
- Mosquito-borne diseases and control
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Identification and Quantification in Food
- Salivary Gland Tumors Diagnosis and Treatment
- Essential Oils and Antimicrobial Activity
- Pneumocystis jirovecii pneumonia detection and treatment
- Advanced X-ray and CT Imaging
- Head and Neck Cancer Studies
- Identity, Memory, and Therapy
- Dental Radiography and Imaging
- Antibiotic Resistance in Bacteria
- Cancer-related gene regulation
- Signaling Pathways in Disease
- Food Safety and Hygiene
Jiangxi Agricultural University
2024
University of the Punjab
2021-2024
University of Chicago
2017-2023
Ghazi University
2023
Abbott (Sweden)
2023
Larkin Community Hospital
2023
Institute of Southern Punjab
2022
Muhammad Nawaz Shareef University of Agriculture
2022
University of Louisville
2021
Indira Gandhi Delhi Technical University for Women
2019
The antimicrobial quantitative structure–activity relationship of plant flavonoids against Gram-positive bacteria was established in our previous works, and the cell membrane confirmed as a major site action. To investigate whether have similar antibacterial effects mechanisms both Gram-negative bacteria, here, minimum inhibitory concentrations (MICs) 37 Escherichia coli were determined using microdilution broth method, then correlation between their lipophilic parameter ACD/LogP or LogD7.40...
The antimicrobial quantitative structure–activity relationship of plant flavonoids against Gram-positive bacteria was established in our previous works, and the cell membrane confirmed as a major site action. To investigate whether have similar antibacterial effects mechanisms both Gram-negative bacteria, here, minimum inhibitory concentrations (MICs) 37 Escherichia coli were determined using microdilution broth method, then correlation between their lipophilic parameter ACD/LogP...
Abstract This study reports the prevalence and antibiotics resistance status of Salmonella detected in raw meat from Lahore, Pakistan. Overall, N = 111 samples, were collected local markets. was recovered 57 (51.35%) including 45.83% poultry, 60% buffalo, 64.28% cow, goat samples. The predominant strains enterica serovars; Typhimurium (45.4%), Typhi (27.2%), Enteritidis (18.1%), identified by VITEK system 16S rRNA gene sequencing. isolates exhibited high to Erythromycin (100%), Cefepime...
The epidemiology and outcomes of community-acquired pneumonia (CAP) in immunocompromised hosts (ICHs) are not well defined. objective this study was to define the CAP ICHs as compared with non-ICHs.This ancillary included a prospective cohort hospitalized adult Louisville residents from 1 June 2014 31 May 2016. An ICH defined per criteria Centers for Disease Control Prevention. Geospatial explored associations between income level, race, age. Mortality non-ICHs evaluated during...
Background Artificial intelligence (AI) has revolutionized diagnostic radiology by improving accuracy, efficiency, and clinical decision-making. While numerous systematic reviews meta-analyses have evaluated the performance of AI-based techniques, particularly traditional machine learning (ML) deep (DL) models, a comprehensive synthesis this evidence is lacking. An umbrella review necessary to integrate compare findings across various imaging applications, offering highest level inform...
Purpose: Squamous cell carcinoma of the head and neck (SCCHN) is a lethal cancer with suboptimal 5-year overall survival approximately 50% surgery and/or definitive chemoradiotherapy. Novel treatments are thus urgently awaited. Immunotherapy checkpoint blockade has emerged as promising option for patients recurrent/metastatic SCCHN; however, it not been investigated in curative-intent setting yet. The purpose this study was to investigate T-cell receptor repertoire tumor microenvironment...
The occurrence of Staphylococcus aureus-induced subclinical mastitis holds significant implications for public health. This specific microorganism possesses a wide array pathogenic factors that enable it to adhere to, colonize, invade, and infect the host. objective current study was assess prevalence S. aureus, determine antimicrobial resistance patterns, identify virulence genes methicillin-resistant aureus (MRSA) strains responsible in bovines. A total 249 milk samples were collected from...
Background: Fever caused by dengue is one of the most important potential viral re-emerging diseases, especially in sub-tropics and tropics, infecting around fifty million people all over world. Dengue virus (DENV) spread through mosquito bite a member genus Flavivirus has four serotypes (DENV-1, 2, 3, 4), which are capable inducing hemorrhagic fever shock syndrome. There several fates infection ranging from asymptomatic to subclinical clinical presentation that may be undistinguishable or...
The antibacterial activities of plant flavonoids have increasingly paid a more attention to. In our previous works, the antimicrobial quantitative structure-activity relationship was established for against gram-positive bacteria, and its major action site confirmed as cell membrane. To understand difference to gram-negative -positive here minimum inhibitory concentrations (MICs) thirty-seven Escherichia coli were determined using microdilution broth method, then correlation between their...
The antibacterial activities of plant flavonoids have increasingly paid a more attention to. antimicrobial quantitative structure-activity relationship was established for against gram-positive bacteria, and its major action site confirmed as the cell membrane in our previous works. To understand whether there are similar modes Gram-negative to -positive here minimum inhibitory concentrations (MICs) thirty-seven Escherichia coli were determined using microdilution broth method, then...
Background/Objectives: Antimicrobial resistance (AMR) poses a significant threat to human health, and combination therapy has proven effective in combating it. It been reported that some plant flavonoids can enhance the antibacterial effects of antibiotics even reverse AMR. This study systematically evaluated synergistic clinical antibiotics. Methods: The activities thirty-seven nine with various antimicrobial mechanisms were determined using microbroth dilution method. Subsequently,...
This study focuses into the possible links between patient demographics, smoking habits, treatment received, and periodontal disease severity before after treatment. A new dataset of 1,000 patients was created, with information on age, status, therapy, whether or not received. To obtain insight correlations variables, descriptive inferential statistical analyses were performed using SPSS. machine learning model also created trained to predict following Despite apparent complexity process,...
Kidney stone detection is a crucial task in medical diagnostics where early identification can mitigate severe health complications. This research employs advanced deep-learning techniques to classify four types of renal ultrasound images: cyst, normal, stone, and tumor. Three pre-trained customized neural network architectures-EANet, InceptionV3, SqueezeNet-are utilized for this purpose. The methodology was rigorously evaluated on testing dataset consisting 3,734 images. Results demonstrate...
The coronavirus disease (COVID-19) pandemic has been caused by the worldwide infectious spread of severe acute respiratory syndrome 2 (SARS-CoV-2).Its mechanism action involves RNA virus implantation into cell's cytoplasm and hijack transcriptional machinery.The infection primarily afflicts pulmonary system, resulting in multiple complications including, but not limited to, ground glass opacities seen on imaging.Characteristic features COVID-19 involve pneumonia, shortness breath, asthma,...
Salmonella is one of the most common causes foodborne diseases among humans worldwide. Animal-derived foods are frequently tested for presence spp. However, detection in meat and its products often hindered due to background normal flora, which may lead false-positive Salmonella. The present study aimed isolate accurately identify from poultry meat. For this purpose, seventy samples were collected Lahore, Pakistan, isolated on selective differential media, identified using biochemical tests...
Cave actinobacteria are relatively less explored and considered as the new targets for discovery of novel antimicrobials, specifically against highly resistant pathogens such extensively drug-resistant (XDR) Salmonella. In this study N=20 isolates were retrieved from least disturbed caves situated at Bahadurkhel Karak, Pakistan (33° 16’ 52” North, 70° 79’ 07” East) 15’ 90” 94’ 72” East). The identified using standard morphological biochemical characterization procedures well by 16S rDNA...
Gibberellins (GA3), as well the basic elements phosphorus (P), nitrogen (N), and potassium (K), are crucial to growth of chili. This study investigates effect different fertilizers plant regulator on morphology chili seedlings. Soil application NPK, urea, SOP, DAP (2.5 g/L) was applied during sowing, N in two splits at sowing after twenty days while foliar GA3 (50 mg/L) fifteen germination. The result five seedlings' traits height (PH), girth (PG), spread (PS), number leaves (NOF), root...
This comparative study delves into the nuanced ways contextual factors impact information retrieval among adolescent boys and girls. The aim is to analyse cognitive processes, memory, learning preferences unique each gender. By examining how they navigate recall within different contexts, research aims contribute valuable insights for educators policymakers, potentially leading tailored strategies development education based on gender-specific needs. sample of consists 30 adolescents (from...
Background/Objectives: Antimicrobial resistance (AMR) has been seriously threatening to human health, and combination therapy proved be an effective strategy fight the AMR. Many plant flavonoids can enhance antibacterial effects of antibiotics, even reverse Our objective was explore combined with antibiotics. Methods: The activities 37 9 clinical antibiotics various antimicrobial mechanisms were determined using microbroth dilution method. Subsequently, 12 presenting definite MICs against...