- Body Image and Dysmorphia Studies
- Opioid Use Disorder Treatment
- Congenital limb and hand anomalies
- Medical Malpractice and Liability Issues
- Poisoning and overdose treatments
- Blood Pressure and Hypertension Studies
- Bipolar Disorder and Treatment
- Oropharyngeal Anatomy and Pathologies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Ethics in Clinical Research
- Sexual Differentiation and Disorders
- Cancer-related molecular mechanisms research
- dental development and anomalies
- Treatment of Major Depression
- Obsessive-Compulsive Spectrum Disorders
- Face Recognition and Perception
- Cleft Lip and Palate Research
- Substance Abuse Treatment and Outcomes
- Evolutionary Psychology and Human Behavior
- Craniofacial Disorders and Treatments
- Neurogenetic and Muscular Disorders Research
- HIV, Drug Use, Sexual Risk
- Genomics and Rare Diseases
- Bone Metabolism and Diseases
- RNA modifications and cancer
University of Pittsburgh
2012-2024
Abstract The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference supporting genomic analyses through semantic similarity machine learning algorithms. HPO has widespread applications in clinical diagnostics translational research, including diagnostics, gene-disease discovery, cohort analytics. In recent years, groups around world have developed translations from English...
Facial imaging and facial recognition technologies, now common in our daily lives, also are increasingly incorporated into health care processes, enabling touch-free appointment check-in, matching patients accurately, assisting with the diagnosis of certain medical conditions. The use, sharing, storage data is expected to expand coming years, yet little documented about perspectives participants regarding these uses. We developed a pair surveys gather public on uses images technologies...
Velopharyngeal dysfunction (VPD) occurs when the muscular soft palate (velum) and lateral pharyngeal walls are physically unable to separate oral nasal cavities during speech production leading hypernasality abnormal reduction. Because VPD is often associated with overt or submucous cleft palate, it could be present as a subclinical phenotype in families history of orofacial clefting. A key assumption this model that manifestations exist on continuum therefore share common etiological...
Mild curvature of the fifth finger (or clinodactyly) is a relatively common trait. While severe forms can cause functional impairment and are feature certain congenital syndromes, mild clinodactyly considered minor morphological variant. Despite exhibiting continuous variation, rarely treated as quantitative Consequently, degree in general population factors that impact this not well understood. In present study, we measured sample 1,295 U.S. adults investigated role sex, age body size. We...
Applications of biometrics in various societal contexts have been increasing the United States, and policy debates about potential restrictions expansions for specific (such as facial recognition DNA identification) intensifying. Empirical data public perspectives on different types can inform these debates. We surveyed 4048 adults to explore regarding experience comfort with six biometrics; providing distinct scenarios; trust social actors use two (facial images DNA) responsibly;...
Poor adherence to depression treatment is common.Understanding determinants of poor therapy crucial ensure optimal clinical outcomes.The aim this study was describe characteristics dosing history in participants with receiving once daily escitalopram.Participants were randomly assigned interpersonal psychotherapy (IPT) or pharmacotherapy.Participants IPT who did not evidence a response remission had escitalopram added their treatment.Adherence pharmacotherapy assessed using an