Olga Mazur
A5085217624- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
- Salmonella and Campylobacter epidemiology
- SARS-CoV-2 and COVID-19 Research
- Vibrio bacteria research studies
- Long-Term Effects of COVID-19
- Vaccine Coverage and Hesitancy
- COVID-19 and Mental Health
- Infant Nutrition and Health
- Diphtheria, Corynebacterium, and Tetanus
- Pneumonia and Respiratory Infections
- Retinal and Optic Conditions
- vaccines and immunoinformatics approaches
- Bacterial Infections and Vaccines
- Pediatric Hepatobiliary Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
Oxford BioMedica (United Kingdom)
2021-2023
Shupyk National Healthcare University of Ukraine
2023
Bila Tserkva National Agrarian University
2023
University of Oxford
2019-2021
Patan Academy of Health Sciences
2019
Patan Hospital
2019
University of Maryland, Baltimore
2019
National Institute for Health Research
2019
Nepal Family Development Foundation
2019
Salmonella Typhi is a major cause of fever in children low- and middle-income countries. A typhoid conjugate vaccine (TCV) that was recently prequalified by the World Health Organization shown to be efficacious human challenge model, but data from efficacy trials areas where endemic are lacking.
BackgroundTyphoid fever remains a major cause of morbidity and mortality in low-income middle-income countries. Vi-tetanus toxoid conjugate vaccine (Vi-TT) is recommended by WHO for implementation high-burden countries, but there little evidence about its ability to protect against clinical typhoid such settings.MethodsWe did participant-masked observer-masked cluster-randomised trial preceded safety pilot phase an urban endemic setting Dhaka, Bangladesh. 150 clusters, each with...
Typhoid fever is a major public health problem in low-resource settings. Vaccination can help curb the disease and might reduce transmission. We have previously reported an interim analysis of efficacy typhoid conjugate vaccine (TCV) Nepali children. Here we report final results after 2 years follow-up.We did participant-masked observer-masked individually randomised trial Lalitpur, Nepal, which 20 019 children aged 9 months to younger than 16 were randomly assigned 1:1 ratio receive single...
Abstract Several COVID-19 vaccines have shown good efficacy in clinical trials, but there remains uncertainty about the of against different variants. Here, we investigate ChAdOx1 nCoV-19 (AZD1222) symptomatic a post-hoc exploratory analysis Phase 3 randomised trial Brazil (trial registration ISRCTN89951424). Nose and throat swabs were tested by PCR participants. Sequencing genotyping performed to determine lineages SARS-CoV-2 circulating during study. Protection any caused Zeta (P.2)...
Typhoid fever is estimated to affect over 20 million people per year worldwide, with infants, children, and adolescents in south-central southeast Asia experiencing the greatest burden of disease. The Vaccine Acceleration Consortium (TyVAC) aims support introduction typhoid conjugate vaccines into Gavi-eligible countries an effort reduce morbidity mortality from typhoid. TyVAC-Nepal a large-scale, participant- observer-blind, individually randomized, controlled trial evaluating efficacy...
The article presents an open multicenter randomized clinical trial to evaluate the effectiveness of drug Bioven, manufactured by «Biopharma Plasma», LLC. This study was conducted in Ukraine on 9 sites. IVIG (trade name – Bioven) used complex therapy patients with pneumonia caused coronavirus infection COVID-19 / SARS-CoV-2, at a dose 0.8-1.0 g kg body weight per day, for two days (course - 1.6-2.0 weight). Bioven confirmed efficacy severe pneumonia. Was achieved faster improvement,...
Background. Currently, there is no internationally approved protocol for anticoagulant therapy (ACT) in patients with COVID-19 that describes the different types of ACT programs depending on severity COVID-19. The objective: to determine optimal programs. Materials and methods. A retrospective analysis was conducted 268 extremely severe who were treated intensive care units. Results. article presents results analysis a very course general unit 2021. 162 died because 106 survived studied...
Abstract Background Universal immunisation is the cornerstone of preventive medicine for children, The World Health Organisation (WHO) recommends diphtheria-tetanus-pertussis (DTP) vaccine administered at 6, 10 and 14 weeks age as part routine immunisation. However, globally, more than 17 unique DTP-containing schedules are in use. New vaccines other diseases continue to be introduced into infant schedule, resulting an increasingly crowded schedule. OptImms trial will assess whether antibody...