Thitisuda Kalawil

ORCID: 0009-0003-1559-2715
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About
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Research Areas
  • Fungal and yeast genetics research
  • Fungal Biology and Applications
  • Microbial Natural Products and Biosynthesis
  • Microbial Metabolic Engineering and Bioproduction
  • Antifungal resistance and susceptibility
  • Biofuel production and bioconversion
  • Plant-Microbe Interactions and Immunity

Chiang Mai University
2024

Abstract Background Spathaspora passalidarum is a yeast with the highly effective capability of fermenting several monosaccharides in lignocellulosic hydrolysates, especially xylose. However, this was shown to be sensitive furfural released during pretreatment and hydrolysis processes lignocellulose biomass. We aimed improve tolerance previously isolated S. CMUWF1−2, which presented thermotolerance no detectable glucose repression, via adaptive laboratory evolution (ALE). Results An adapted...

10.1186/s12934-024-02352-x article EN cc-by Microbial Cell Factories 2024-03-13

ABSTRACT Talaromycosis is a fungal infection caused by an opportunistic dimorphic fungus Talaromyces marneffei . During infection, T. resides inside phagosomes of human host macrophages where the encounters nutrient scarcities and host-derived oxidative stressors. Previously, we showed that deletion acuK, gene encoding Zn(2)Cys(6) transcription factor, decreased ability for to defend against macrophages, as well growth impairment in on both low iron-containing medium gluconeogenic...

10.1101/2024.04.10.588979 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2024-04-11

Talaromyces marneffei is a thermally dimorphic fungus that can cause life-threatening systemic mycoses, particularly in immunocompromised individuals. Fungal homeobox transcription factors control various developmental processes, including the regulation of sexual reproduction, morphology, metabolism, and virulence. However, function proteins T. has not been fully explored. Here, we searched genome for total predicted their biological relevance by performing gene expression analysis...

10.3390/jof10100687 article EN cc-by Journal of Fungi 2024-09-30

Talaromycosis is a fungal infection caused by an opportunistic dimorphic fungus Talaromyces marneffei . During infection, T resides inside phagosomes of human host macrophages where the encounters nutrient scarcities and host-derived oxidative stressors. Previously, we showed that deletion acuK , gene encoding Zn(2)Cys(6) transcription factor, decreased ability for to defend against macrophages, as well growth impairment in on both low iron-containing medium gluconeogenic...

10.1371/journal.pntd.0012145 article EN cc-by PLoS neglected tropical diseases 2024-09-04
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