A5003464331- Supramolecular Self-Assembly in Materials
- Polydiacetylene-based materials and applications
- Antimicrobial Peptides and Activities
- Nanoplatforms for cancer theranostics
- Advanced biosensing and bioanalysis techniques
- Advanced Drug Delivery Systems
- Silk-based biomaterials and applications
- Nanoparticle-Based Drug Delivery
- Polymer Surface Interaction Studies
- RNA Interference and Gene Delivery
- Graphene and Nanomaterials Applications
- Molecular Junctions and Nanostructures
- Antimicrobial agents and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Inhalation and Respiratory Drug Delivery
- Nanoparticles: synthesis and applications
- Luminescence and Fluorescent Materials
- Chemical Synthesis and Analysis
- Diatoms and Algae Research
University of Chinese Academy of Sciences
2023-2024
Beijing National Laboratory for Molecular Sciences
2023-2024
Chinese Academy of Sciences
2023-2024
National Center for Nanoscience and Technology
2022-2023
University of Science and Technology Beijing
2022
Antimicrobial agents are massively used to disinfect the pathogen contaminated surfaces since Corona Virus Disease 2019 (COVID-19) outbreak. However, their defects of poor durability, strong irritation, and high environmental accumulation exposed. Herein, a convenient strategy is developed fabricate long-lasting target-selective antimicrobial agent with special hierarchical structure through bottom-up assembly natural gallic acid arginine surfactant. The starts from rodlike micelles, further...
Abstract To endow non‐antibacterial molecules with highly efficient bactericide activity is an important but challenging issue. Herein, a kind of cell‐penetrating peptide octa‐arginine (R8) found to be effective in activating antibacterial ability when assembling anionic surfactant sodium dodecyl sulfate (SDS), while individual R8 or SDS shows poor no ability. By combined electrostatic, hydrogen bond, and hydrophobic interactions, associate into wormlike micelle lamellar structure by forming...
Nanomaterials (NMs) inevitably adsorb proteins in blood and form "protein corona" upon intravenous administration as drug carriers, potentially changing the biological properties intended functions. Inspired by anti-adhesion of natural proteins, herein, we employed one-bead one-compound (OBOC) combinatorial peptide library method to screen peptides (AAPs) against proteins. The beads displaying random were screened with three fluorescent-labeled plasma nonfluorescence beads, presumed have...
Transformable peptides (TPs) are biomedical materials with unique structures and diverse functionalities that have drawn great interest in science nanomedicine. Here, we design a series of TPs five self-assembling sequences conjugated the hydrophobic unit bis(pyrene) targeting sequence RGD, study transformable features induced by ligand (RGD)-receptor (integrin or Ca2+) interactions. able to self-assemble into nanoparticles nanosheets then transform nano-aggregates nanofibers RGD-Ca2+...
Silver, as the oldest antibacterial material, has been almost replaced by other alternatives for its insufficient activity or potential side-effects on ecosystem due to over-release of Ag ions (Ag+). Herein, a facile and general strategy is developed on-substrate fabricate silver coordination polymer nanowire arrays (Ag CPN) simply immersing Ag-containing substrates into cationic surfactant solution at room temperature. Such CPN not only provides high-surface-area nano-biointerfaces...
Binding-induced fibrillogenesis (BIF) peptides have a promising future in biomedicine due to the processiblity situ vivo, which bind specific trigger and self-assemble into nanofibrous structures (BIF process) with excellent physical/biological functions. Alkyl chains BIF as hydrophobic tails an important effect on self-assembly behaviors of peptides. Herein, (trigger: Ca2+ or integrin) different alkyl are designed explore influence hydrophobicity (Abbreviation BIF4, BIF8, BIF16 for 4, 8, 16...
The formation and transformation of antifungal peptide (AFP) nanoparticles (NPs) are presented. AFP self-assembles into NPs (i). target bind to chitin (ii). transform fibrous networks in solution (iii) on the surface fungal cells (iii′).