A5052024039- Extracellular vesicles in disease
- Bone and Joint Diseases
- MicroRNA in disease regulation
- Nanoparticles: synthesis and applications
- Conducting polymers and applications
- Mesenchymal stem cell research
- Polymer Nanocomposite Synthesis and Irradiation
- Immune cells in cancer
Shanghai First People's Hospital
2022-2025
Shanghai Jiao Tong University
2022-2023
Recently, bone marrow endothelial cells (BMECs) were found to play an important role in regulating homeostasis. However, few studies utilized BMECs treat metabolic diseases including osteoporosis. Here, we reported bioinspired nanovesicles (BNVs) prepared from human induced pluripotent stem cells-derived under hypoxia culture through extrusion approach. Abundant membrane C-X-C motif chemokine receptor 4 conferred these BNVs bone-targeting ability and the homology facilitated BMEC tropism....
ABSTRACT The treatment of spinal cord injury is crucial to prevent further damage and improve long‐term outcomes, as early intervention can stabilize the spine, control inflammation, facilitate recovery function. In present study, we synthesized a new metallic NPs investigated ability treat injury. bimetallic nickel/copper were using aqueous extract Artemisia annua . was chemically characterized. Bands at wavenumbers 1053, 1377–1664, 2922, 3417 cm −1 reveal functional groups’ presence C‐O,...
Bone fracture repair is a multiphased regenerative process requiring paracrine intervention throughout the healing process. Mesenchymal stem cells (MSCs) play crucial role in cell-to-cell communication and regeneration of tissue, but their transplantation difficult to regulate. The processes that occur MSC-derived extracellular vesicles (MSC-EVs) have been exploited for this study. primary goal was determine whether EVs secreted by TGF-β1-stimulated MSCs (MSCTGF-β1-EVs) exhibit greater...